Using Mathematical Models To Assess The Impact Of Interventions To Reduce Sexually Transmitted Infections In Australia
Funder
National Health and Medical Research Council
Funding Amount
$562,276.00
Summary
Sexually transmitted infections (STIs) are an increasing public health problem in Australia. Australia's recent National Transmissible Infections Strategy identified chlamydia control, STI prevention in gay men and STIs in Aboriginal and Torres Strait Islander communities as priority areas. We propose to develop mathematical models of STI transmission and use these to help understand and identify the most cost-effective interventions to reduce the impact of STIs on Australian populations.
Integrity prediction of ground precision surfaces. This project aims to establish a new approach to enable a reliable and accurate prediction of precision surface grinding. Precision grinding is often the final step in the manufacturing chains for a broad range of metal, ceramic, optical glass and semiconductor components, which must have ultra-high surface integrity and accurate dimensions. To date, the surface integrity of a ground component cannot be predicted due to the involvement of many r ....Integrity prediction of ground precision surfaces. This project aims to establish a new approach to enable a reliable and accurate prediction of precision surface grinding. Precision grinding is often the final step in the manufacturing chains for a broad range of metal, ceramic, optical glass and semiconductor components, which must have ultra-high surface integrity and accurate dimensions. To date, the surface integrity of a ground component cannot be predicted due to the involvement of many random factors and variables in a precision surface grinding process, resulting in high failure rates and processes requiring repeated surface measurements. The novel approach for surface integrity prediction developed by this project will make a vital step forward in advancing the discipline of precision surfacing, establish a new knowledge base and bring about significant technological impacts to the manufacturing industry.Read moreRead less
A miniaturised laser manipulator for ultra-precise and pain-free dentistry. This project aims to develop a miniaturized high-precision laser robotic device that can fit comfortably in the mouth to perform pain-free, vibration-free dental operations by utilising silicon-carbide on silicon technology to create a millimetre-sized two-axis controllable, highly-reflective mirror robust to high-power ultra-short laser pulses. This project expects to generate new knowledge in micro-mirror control using ....A miniaturised laser manipulator for ultra-precise and pain-free dentistry. This project aims to develop a miniaturized high-precision laser robotic device that can fit comfortably in the mouth to perform pain-free, vibration-free dental operations by utilising silicon-carbide on silicon technology to create a millimetre-sized two-axis controllable, highly-reflective mirror robust to high-power ultra-short laser pulses. This project expects to generate new knowledge in micro-mirror control using optically excited piezo-resistive sensors, and cold femtosecond laser ablation of hard dental tissue. Expected outcomes include a working prototype for laser removal of tooth materials at speeds exceeding dental drills, providing benefits in miniaturized laser devices and ultimately removing pain from dental procedures. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100016
Funder
Australian Research Council
Funding Amount
$490,000.00
Summary
Multi-scale fabrication facility for complex three-dimensional surface generation from nano to macro dimensions. This facility will support advances in the manufacturing of free-form surfaces with submicron features. Its unique characteristics, such as the universal profiling ability and nanometre accuracy across large dimensions, will enable many science and engineering innovations which are presently impossible to be realised in Australia.
An integral approach enabling the defect-free manufacture of microlens arrays. Free-form microlens arrays are of central importance to the advancement of science and frontier technologies such as electronics, optics, telecommunication, biotechnology, medical surgery, energy generation, agriculture, resource exploration, environment protection and security. Using an integral approach coupling processing-microstructure-property modelling, multi-scale mechanics and damage-free mould development. Th ....An integral approach enabling the defect-free manufacture of microlens arrays. Free-form microlens arrays are of central importance to the advancement of science and frontier technologies such as electronics, optics, telecommunication, biotechnology, medical surgery, energy generation, agriculture, resource exploration, environment protection and security. Using an integral approach coupling processing-microstructure-property modelling, multi-scale mechanics and damage-free mould development. This research project will establish novel theories and technologies for the defect-free manufacture of microlens arrays. The research outcomes will lay the foundation for defect-free fabrication of a wide class of high-integrity systems.Read moreRead less
Diamond lasers for precision applications. Diamond lasers for precision applications. The project aims to create single mode lasers of ultrahigh spectral brightness. Single-mode lasers could improve many areas of science and technology, but existing technologies do not meet all performance requirements. This project will harness the intrinsic properties of diamond Raman lasers to increase the wavelength reach, power and stability of single mode lasers. The expected outcome is laser technology th ....Diamond lasers for precision applications. Diamond lasers for precision applications. The project aims to create single mode lasers of ultrahigh spectral brightness. Single-mode lasers could improve many areas of science and technology, but existing technologies do not meet all performance requirements. This project will harness the intrinsic properties of diamond Raman lasers to increase the wavelength reach, power and stability of single mode lasers. The expected outcome is laser technology that satisfies the needs of emerging markets, for example in gas sensing and atom cooling.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100036
Funder
Australian Research Council
Funding Amount
$310,000.00
Summary
Super high speed grinding facility for difficult-to-machine materials and structures. This unique system will enable the manufacture of difficult-to-machine materials and structures with high quality and high productivity. It will support ground-breaking research activities across the country and help promote the strategic collaborations within Australian manufacturing society.
Creating Sustainable Healthcare: Ensuring New Diagnostics Avoid Harms, Improve Outcomes, And Direct Resources Wisely
Funder
National Health and Medical Research Council
Funding Amount
$2,497,658.00
Summary
Novel imaging, biomarkers and genomic tests for risk assessment and early detection are emerging as major forces for change in clinical practice. While providing advances and new benefits for patients, new technologies can also have harmful, unintended consequences - overdiagnosis and overtreatment. This multidisciplinary CRE will investigate how to respond to emerging technologies to optimise health outcomes while avoiding harms and directing healthcare resources wisely.
The Validation Of A Culturally-specific Measure To Identify Depression In Aboriginal And Torres Strait Islander People With Or Without Chronic Disease
Funder
National Health and Medical Research Council
Funding Amount
$658,971.00
Summary
The project aims to determine whether a short, free-to-use, questionnaire about depression that has been adapted for use with Aboriginal and Torres Strait Islander people, accurately identifies depression in this population. Specifically we aim to test whether this measure is suitable for use in primary care settings with Aboriginal and Torres Strait Islander people with or without chronic disease.
Development Of A New High Throughput Screen For Drug Binding To HERG K+ Channels
Funder
National Health and Medical Research Council
Funding Amount
$351,320.00
Summary
Inadvertent drug block of hERG, a potassium channel in the heart, can cause cardiac arrhythmias and sudden cardiac death. Screening for hERG toxicity has become a major hurdle for development of new drugs. We will use a mutant hERG protein that has enhanced drug binding to develop a high throughput test for hERG toxicity. Identification of dangerous drugs early in the drug discovery process will save the pharmaceutical industry millions of dollars in the costs of brining new drugs to market.