Combined optical and electrical stimulation of auditory neurons. The bionic ear, which has now helped to improve the hearing of over 200,000 people worldwide, is a great example of Australian innovation success. This project aims to develop the fundamental technology that will underpin the next generation of these devices using a combination of infrared light and electrical signals to stimulate auditory nerves.
Scaling microfluidics for cell manufacture. Scaling microfluidics for cell manufacture. This project aims to scale microfluidic devices for cell manufacture. Large-scale cell manufacturing processes (cell selection, gene transfer and culture expansion) are expensive, multistep and labour-intensive processes. Lab-on-a-chip devices can automate and integrate these complex processes at microscale. This project will evaluate a prototype bioreactor. This research is expected to make cell therapies ch ....Scaling microfluidics for cell manufacture. Scaling microfluidics for cell manufacture. This project aims to scale microfluidic devices for cell manufacture. Large-scale cell manufacturing processes (cell selection, gene transfer and culture expansion) are expensive, multistep and labour-intensive processes. Lab-on-a-chip devices can automate and integrate these complex processes at microscale. This project will evaluate a prototype bioreactor. This research is expected to make cell therapies cheap enough to become standard treatment, which would benefit patients with diseases that are incurable by conventional therapies (surgery and drug treatments). It should also benefit the Australian advanced manufacturing sector, particularly biopharmaceutical and cell therapy industries.Read moreRead less
Integration of DNA switches into wearables for smart chemical monitoring. This project addresses the scientific challenge of real-time monitoring of dynamic biological changes in the secretions found in sweat. By creating a wearable wireless device to monitor chemicals which interests Nutromics, using a novel electronic skin technology platform, the work aims to generate new knowledge of physiological changes in sweat secretions. Lying at the interface of analytical chemistry, functional materia ....Integration of DNA switches into wearables for smart chemical monitoring. This project addresses the scientific challenge of real-time monitoring of dynamic biological changes in the secretions found in sweat. By creating a wearable wireless device to monitor chemicals which interests Nutromics, using a novel electronic skin technology platform, the work aims to generate new knowledge of physiological changes in sweat secretions. Lying at the interface of analytical chemistry, functional materials and biomedical engineering, the project will contribute to the training of young researchers in these emerging technologies which interest Nutromics Pty Ltd. The project will improve Australia's standing in technology around wearable devices, improving our global competitive edge with economic and scientific impact.Read moreRead less
Haemodynamic investigation of flow diverter stents for the treatment of intracranial aneurysms. This project will explore the engineering of a flow diverter, an endovascular device for the treatment of brain aneurysms. The project will determine the optimal design of new types of flow diverters, which in turn could improve the effectiveness of treatments, thus reducing the associated costs of cerebral haemorrhage and stroke.
A novel scintillating optical fibre array for cancer imaging and therapy. This project aims to realise a next-generation detector technology that delivers the first fully integrated solution to the X-ray imaging and dose measurement needs of cancer radiation therapy. It is planned that this will be achieved by optimising an experimental prototype device employing a scintillating optical fibre array to generate an optical signal that preserves a tissue-equivalent detector response. The acquired d ....A novel scintillating optical fibre array for cancer imaging and therapy. This project aims to realise a next-generation detector technology that delivers the first fully integrated solution to the X-ray imaging and dose measurement needs of cancer radiation therapy. It is planned that this will be achieved by optimising an experimental prototype device employing a scintillating optical fibre array to generate an optical signal that preserves a tissue-equivalent detector response. The acquired digital image can thus be used to simultaneously verify geometric accuracy (correct patient positioning) and dosimetric accuracy (correct dose distribution). This is not currently possible with existing X-ray detector technology and offers an improvement in treatment accuracy.Read moreRead less
Quantitative structural health assessment of large membrane-like structures. This project aims to develop a new approach, based on remote sensing and computational modelling, to assess and manage the structural health of large floating covers used for odour control and biogas harvesting to prevent unexpected failures. The project has potential benefits for high-value-added manufacturing and maintenance of these floating covers by Australian industry.
Foundation technology for quantum measurement, sensing and computing. This project will advance quantum control of cold ions, atoms and diamond colour centres for application of quantum science to high-tech problems, from ion-based quantum computing to diamond-based quantum imaging inside living cells.
Optical technology for quantum science. This project aims to develop and commercialise optical cavity and frequency stabilisation technology to generate laser light at new and precise wavelengths. Australia plays a leading role internationally in quantum science, a burgeoning area of research where fundamental quantum mechanical principles underpin exciting new technological applications, such as ion-based quantum computing, ultracold atom sensing for geo-exploration and defence, and nanoscale i ....Optical technology for quantum science. This project aims to develop and commercialise optical cavity and frequency stabilisation technology to generate laser light at new and precise wavelengths. Australia plays a leading role internationally in quantum science, a burgeoning area of research where fundamental quantum mechanical principles underpin exciting new technological applications, such as ion-based quantum computing, ultracold atom sensing for geo-exploration and defence, and nanoscale imaging inside living human cells. This project aims to continue and develop this role.Read moreRead less
Improved effectiveness of cochlear implants through new simultaneous stimulation techniques. Cochlear implants have brought the gift of hearing to 250,000 people worldwide and are an excellent example of Australian innovation. This project will examine an improved "high fidelity" stimulation strategy with the objective of defining a safe stimulus range for clinical use and providing a commercial advantage for Cochlear Ltd.
Agile synthesizers for quantum computing, simulation and sensing. The project aims to develop breakthrough technology for generating the complex radio and microwave pulses that underpin the revolution in quantum computing and quantum sensing. Quantum technologies are rapidly emerging from laboratory to real-world applications including neural imaging, defence surveillance, and mining exploration, but further advances require increased precision and flexibility in controlling the quantum states ....Agile synthesizers for quantum computing, simulation and sensing. The project aims to develop breakthrough technology for generating the complex radio and microwave pulses that underpin the revolution in quantum computing and quantum sensing. Quantum technologies are rapidly emerging from laboratory to real-world applications including neural imaging, defence surveillance, and mining exploration, but further advances require increased precision and flexibility in controlling the quantum states at the heart of these new capabilities. Our innovative and more flexible approach to signal generation requires a fraction of the size, weight, power and cost of conventional approaches, enabling the translation of quantum technology to commercial practicality.Read moreRead less