A miniaturised laser manipulator for ultra-precise and pain-free dentistry. This project aims to develop a miniaturized high-precision laser robotic device that can fit comfortably in the mouth to perform pain-free, vibration-free dental operations by utilising silicon-carbide on silicon technology to create a millimetre-sized two-axis controllable, highly-reflective mirror robust to high-power ultra-short laser pulses. This project expects to generate new knowledge in micro-mirror control using ....A miniaturised laser manipulator for ultra-precise and pain-free dentistry. This project aims to develop a miniaturized high-precision laser robotic device that can fit comfortably in the mouth to perform pain-free, vibration-free dental operations by utilising silicon-carbide on silicon technology to create a millimetre-sized two-axis controllable, highly-reflective mirror robust to high-power ultra-short laser pulses. This project expects to generate new knowledge in micro-mirror control using optically excited piezo-resistive sensors, and cold femtosecond laser ablation of hard dental tissue. Expected outcomes include a working prototype for laser removal of tooth materials at speeds exceeding dental drills, providing benefits in miniaturized laser devices and ultimately removing pain from dental procedures. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100060
Funder
Australian Research Council
Funding Amount
$638,853.00
Summary
High speed multi modal in-situ Transmission Electron Microscopy platform. This project aims to establish an in situ transmission electron microscope that will allow the atomic scale imaging of materials, while simultaneously measuring physical, chemical, electrical and optical properties, using a novel combination of cutting edge in-situ sample holders and an instrument mounted laser system. The instrument will be optimised for imaging of dynamic phenomena and the combination of spatial resoluti ....High speed multi modal in-situ Transmission Electron Microscopy platform. This project aims to establish an in situ transmission electron microscope that will allow the atomic scale imaging of materials, while simultaneously measuring physical, chemical, electrical and optical properties, using a novel combination of cutting edge in-situ sample holders and an instrument mounted laser system. The instrument will be optimised for imaging of dynamic phenomena and the combination of spatial resolution in the picometre scale, with microsecond level temporal resolution will be unique. The instrument will accelerate research into hydrogen production and carbon dioxide transformation, and thus support Australia's move to a more sustainable economy. Read moreRead less
X-ray Ghost Imaging and Tomography. This project aims to achieve safer, faster, and cheaper 3D X-ray imaging through a technique known as ghost imaging. X-ray imaging provides valuable information about internal structures, however, X-rays are carcinogenic and exposure (or dose) should be limited. Ghost imaging is an unconventional technique developed with visible light that has many potential benefits over conventional imaging. This research group are world leaders in ghost imaging and expect t ....X-ray Ghost Imaging and Tomography. This project aims to achieve safer, faster, and cheaper 3D X-ray imaging through a technique known as ghost imaging. X-ray imaging provides valuable information about internal structures, however, X-rays are carcinogenic and exposure (or dose) should be limited. Ghost imaging is an unconventional technique developed with visible light that has many potential benefits over conventional imaging. This research group are world leaders in ghost imaging and expect to develop software and hardware techniques to realise its potential and extend it to ghost tomography. The focus of this project is on reducing cancer risk in medical imaging, and allowing real-time quality control for 3D printing in safety-critical industries such as aerospace.Read moreRead less
Motion-adaptive PET technology for brain imaging of freely moving mice. This project aims to develop new brain imaging technology that adapts to and corrects for the motion of a responsive, freely moving mouse. Current technology requires the subject to be unconscious, precluding the use of imaging to study signalling pathways activated by external stimuli during cognitive and behavioural tasks. By harnessing new radiation detector, motion tracking and computational technologies, the project exp ....Motion-adaptive PET technology for brain imaging of freely moving mice. This project aims to develop new brain imaging technology that adapts to and corrects for the motion of a responsive, freely moving mouse. Current technology requires the subject to be unconscious, precluding the use of imaging to study signalling pathways activated by external stimuli during cognitive and behavioural tasks. By harnessing new radiation detector, motion tracking and computational technologies, the project expects to bridge this technology gap and provide significant technical and conceptual advances in the field. This will provide important benefits, such as equipping neuroscientists with new tools to answer fundamental questions about how the mammalian brain regulates behavioural adaptation to a changing environment.Read moreRead less
A New Nano Tip Fabrication Technique for Atomic Force Microscopy. This project aims to develop a new fabrication technique for high-aspect-ratio (long and sharp) tips for atomic force microscopy. The technique is expected to overcome the current fabrication limitation, that is fabricating one tip at a time which is unsuitable for batch fabrication. The proposed technique can be scaled up to mass produce nano tips. The technique is expected to create new commercial products and intellectual prope ....A New Nano Tip Fabrication Technique for Atomic Force Microscopy. This project aims to develop a new fabrication technique for high-aspect-ratio (long and sharp) tips for atomic force microscopy. The technique is expected to overcome the current fabrication limitation, that is fabricating one tip at a time which is unsuitable for batch fabrication. The proposed technique can be scaled up to mass produce nano tips. The technique is expected to create new commercial products and intellectual property. This innovation will lead to the emergence of breakthrough technologies in nanofabrication and nanomaterials synthesis. The benefits to Australia include new job opportunities and the development of local expertise in the field.Read moreRead less
Dynamic Mechano-Microscopy for use in Mechanobiology . We will develop an innovative microscope that will enable new discoveries in biology. Most microscopes form images of a sample's optical properties, instead we will image a sample's mechanical properties. The reason our novel approach is needed is that cell behaviour depends on the stiffness of it's environment, but current microscopes are unable to image this. Our microscope will provide insights in biology that can improve our understandi ....Dynamic Mechano-Microscopy for use in Mechanobiology . We will develop an innovative microscope that will enable new discoveries in biology. Most microscopes form images of a sample's optical properties, instead we will image a sample's mechanical properties. The reason our novel approach is needed is that cell behaviour depends on the stiffness of it's environment, but current microscopes are unable to image this. Our microscope will provide insights in biology that can improve our understanding of cells, the building blocks of life. We will achieve this by: 1. Developing a microscope that combines microscopic resolution with rapid imaging; 2: Developing the capability to image both within the cell and its surrounding environment; and 3. Using our microscope to make discoveries in biology.Read moreRead less
Innovative Electrohydrodynamic Atomisation for Improved Nasal Drug Delivery. Inhalation offers high and rapid drug absorption into the bloodstream. This project aims to establish key technologies for a revolutionary system in inhaled nanomedicine delivery. The study will investigate the underlying physics of nanoparticles to create a world-first electrostatic nebuliser, enabling the more effective drug delivery. This technique is expected to overcome the current limitations by providing better c ....Innovative Electrohydrodynamic Atomisation for Improved Nasal Drug Delivery. Inhalation offers high and rapid drug absorption into the bloodstream. This project aims to establish key technologies for a revolutionary system in inhaled nanomedicine delivery. The study will investigate the underlying physics of nanoparticles to create a world-first electrostatic nebuliser, enabling the more effective drug delivery. This technique is expected to overcome the current limitations by providing better control over the size and charge of delivered drugs. The outcomes of this project will benefit pharmaceutical companies in developing products with more efficient nasal delivery of advanced drugs, vaccines, and nanocariers, make it easier for doctors to prescribe, and benefit patients with more accurate dosages.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230100178
Funder
Australian Research Council
Funding Amount
$453,913.00
Summary
Fast, lightweight and live nanopore sequencing analysis. This project aims to address limitations in nanopore sequencing (latest emerging technology in genomics) by applying advanced computational methods. This project expects to create new knowledge in bioinformatics and computer science through innovative approaches that leverage the live data streaming capability of nanopore devices to deliver results rapidly, or in real-time. Expected outcomes include improved, highly efficient analysis meth ....Fast, lightweight and live nanopore sequencing analysis. This project aims to address limitations in nanopore sequencing (latest emerging technology in genomics) by applying advanced computational methods. This project expects to create new knowledge in bioinformatics and computer science through innovative approaches that leverage the live data streaming capability of nanopore devices to deliver results rapidly, or in real-time. Expected outcomes include improved, highly efficient analysis methods and designs for future creation of custom computer hardware for nanopore analysis. This will facilitate widespread adoption of nanopore technology in bioscience research and applied domains (health, agriculture, ecology, biosecurity and forensics), including for portable in-the-field applications. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240101090
Funder
Australian Research Council
Funding Amount
$433,217.00
Summary
In-depth Investigation of Lithium Dendrite Formation Processes. Battery failure is mainly derived from uncontrollable lithium dendrite formation. This project aims to investigate fundamental lithium dendrite formation mechanism by utilizing a novel in-situ transmission electron microscopy cell. This project expects to build a new set up which is capable of simultaneous in-situ electrical and nanomechanical measurements of lithium dendrite growth. This project aims to reveal how lithium dendrite ....In-depth Investigation of Lithium Dendrite Formation Processes. Battery failure is mainly derived from uncontrollable lithium dendrite formation. This project aims to investigate fundamental lithium dendrite formation mechanism by utilizing a novel in-situ transmission electron microscopy cell. This project expects to build a new set up which is capable of simultaneous in-situ electrical and nanomechanical measurements of lithium dendrite growth. This project aims to reveal how lithium dendrite growth is affected by different surface modifications on the commercial graphite electrodes. The success of the project will lead to a fundamental understanding of the lithium dendrite formation mechanism, enabling the construction of significantly safer batteries.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100507
Funder
Australian Research Council
Funding Amount
$444,471.00
Summary
Integrated active microcantilevers for high-throughput nanometrology. This project aims to develop a new versatile, high-performance microsensor platform and microscopy method for measuring nano-scale structures. The proposed microscopy tool is expected to significantly increase imaging speed and miniaturize system footprint, thereby enabling high-throughput quality control of semiconductor devices. The expected outcome is a highly-scalable and low-cost imaging system that will close the technol ....Integrated active microcantilevers for high-throughput nanometrology. This project aims to develop a new versatile, high-performance microsensor platform and microscopy method for measuring nano-scale structures. The proposed microscopy tool is expected to significantly increase imaging speed and miniaturize system footprint, thereby enabling high-throughput quality control of semiconductor devices. The expected outcome is a highly-scalable and low-cost imaging system that will close the technology gap between fabrication and inspection at the nanoscale. The benefits to Australia should include the potential for commercialization to develop this next-generation microscopy tool in high-value market sectors.Read moreRead less