Discovery Early Career Researcher Award - Grant ID: DE150100564
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Vascularized tumour models to elucidate the delivery of nanomedicine agents. This inter-disciplinary project aims to develop advances in in vitro models aimed at elucidating the delivery and transport of diagnostic and therapeutic nanomedicine agents in tumour tissues. The project aims to build on advanced tissue engineering principles and state-of-the-art micro-fabrication technologies to remove the limitation associated with animal studies and provide unprecedented mechanistic insights into th ....Vascularized tumour models to elucidate the delivery of nanomedicine agents. This inter-disciplinary project aims to develop advances in in vitro models aimed at elucidating the delivery and transport of diagnostic and therapeutic nanomedicine agents in tumour tissues. The project aims to build on advanced tissue engineering principles and state-of-the-art micro-fabrication technologies to remove the limitation associated with animal studies and provide unprecedented mechanistic insights into the delivery, transport and binding of nanomedicines into tumour tissues.Read moreRead less
Nanolayer Degradation Deposits on Cold Rolled Steel Strip: The Influence of Rolling Oil Emulsions in Sequential Oxidative and Reductive Environments. Cold rolled steel strip, produced by BHP Steel, is a precursor material for production of internationally recognised Australian products ZINCALUMER Steel and COLORBONDR Steel. Lubricating oils supplied by Quaker Chemical are used during the cold rolling process. When exposed to the direct fired annealing process, nanolayer surface residues can de ....Nanolayer Degradation Deposits on Cold Rolled Steel Strip: The Influence of Rolling Oil Emulsions in Sequential Oxidative and Reductive Environments. Cold rolled steel strip, produced by BHP Steel, is a precursor material for production of internationally recognised Australian products ZINCALUMER Steel and COLORBONDR Steel. Lubricating oils supplied by Quaker Chemical are used during the cold rolling process. When exposed to the direct fired annealing process, nanolayer surface residues can develop from rolling oil films and adversely affect subsequent steel surface wetting by the molten zinc alloy. This collaborative research project will investigate the fundamental nature of nanolayer residue formation, using advanced thermal and surface analysis techniques, with the aim of determining the factors influencing residue formation and reducing their impact.Read moreRead less
High shear fluid flow driving carbon foundry for advanced manufacturing. This project aims to develop versatile continuous flow thin film microfluidic device technology for harnessing contact electrification generated by sub-micron high shear flows in fabricating novel and high-performance nano-carbons for which current methods are ineffective or impossible. This project expects to generate new knowledge on complex vortex fluid fields, their intricate interactions with external electric and magn ....High shear fluid flow driving carbon foundry for advanced manufacturing. This project aims to develop versatile continuous flow thin film microfluidic device technology for harnessing contact electrification generated by sub-micron high shear flows in fabricating novel and high-performance nano-carbons for which current methods are ineffective or impossible. This project expects to generate new knowledge on complex vortex fluid fields, their intricate interactions with external electric and magnetic fields and carbon nanostructure formation. Expected outcomes for this project include exquisite control on reforming nanocarbon with tuneable properties and unprecedented hetero-structures. This should provide significant benefits, such as in generating new processes and products for advanced manufacturing. Read moreRead less
Nanoscale silicon field-effect transistor diagnostic technology. This project aims to overcome barriers to the implementation of silicon field-effect transistor biosensors. It will investigate the biosensors’ physical and structural properties. This knowledge, combined with technological and conceptual advances, could foster the development of an advanced and translational point-of-care diagnostic technology to rapidly and sensitively detect malignant tissues. Such technology would have commerci ....Nanoscale silicon field-effect transistor diagnostic technology. This project aims to overcome barriers to the implementation of silicon field-effect transistor biosensors. It will investigate the biosensors’ physical and structural properties. This knowledge, combined with technological and conceptual advances, could foster the development of an advanced and translational point-of-care diagnostic technology to rapidly and sensitively detect malignant tissues. Such technology would have commercial potential and important societal benefits.Read moreRead less
ARC Centre of Excellence for Nanoscale BioPhotonics. The CNBP brings together physicists, chemists and biologists focused on a grand challenge controlling nanoscale interactions between light and matter to probe the complex and dynamic nanoenvironments within living organisms. The emerging convergence of nanoscience and photonics offers the opportunity of using light to interrogate nanoscale domains, providing unprecedentedly localised measurements. This will allow biological scientists to unde ....ARC Centre of Excellence for Nanoscale BioPhotonics. The CNBP brings together physicists, chemists and biologists focused on a grand challenge controlling nanoscale interactions between light and matter to probe the complex and dynamic nanoenvironments within living organisms. The emerging convergence of nanoscience and photonics offers the opportunity of using light to interrogate nanoscale domains, providing unprecedentedly localised measurements. This will allow biological scientists to understand how single cells react to and communicate with their surroundings. This science will underpin a new generation of devices capable of probing the response of cells within individuals to environmental conditions or treatment, creating innovative and powerful new sensing platforms.Read moreRead less
Nanotribology and Nanorheometry: A Fundamental Study of the Dynamic Interactions of Particles and Surfaces at the Molecular Level. Friction and deformation occur from the mutual motion and interaction of microscopic particles and surfaces. This research aims to develop new theories and measurement techniques for these non-equilibrium phenomena by combining mathematical analysis and numerical computations with dynamic force measurement, surface modification, and surface characterisation on nanom ....Nanotribology and Nanorheometry: A Fundamental Study of the Dynamic Interactions of Particles and Surfaces at the Molecular Level. Friction and deformation occur from the mutual motion and interaction of microscopic particles and surfaces. This research aims to develop new theories and measurement techniques for these non-equilibrium phenomena by combining mathematical analysis and numerical computations with dynamic force measurement, surface modification, and surface characterisation on nanometre and molecular length scales. These insights and data will be critically important in designing low-friction surfaces that save energy and wear, in developing nanoscopic probes for the mechanical and structural properties of soft polymeric and bio-materials, and in making high performance coatings that control adhesion and particle aggregation in technologically advanced applications.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0454249
Funder
Australian Research Council
Funding Amount
$157,004.00
Summary
Specialist Analysis Facility for the Development of New Nanotechnologies. Nanotechnology is a developing technology with a limited number of academic research groups working in this field. Advanced infrastructure is requested for the characterisation and analysis of novel polymers, nanomaterials and biomaterials. The specialist applications herein demand both characterisation and processing control at the nanoscopic level and will greatly enhance teaching and core research capability within Fl ....Specialist Analysis Facility for the Development of New Nanotechnologies. Nanotechnology is a developing technology with a limited number of academic research groups working in this field. Advanced infrastructure is requested for the characterisation and analysis of novel polymers, nanomaterials and biomaterials. The specialist applications herein demand both characterisation and processing control at the nanoscopic level and will greatly enhance teaching and core research capability within Flinders University and the University of South Australia. This equipment will allow the universities to carry out this research in a unique manner. Other researchers cannot offer the synergy of synthesis, processing and characterisation of nanomaterials and biomaterials as described in this project.Read moreRead less
Nanoscale Particle Control by Rigid Biomineralised Surfaces. The proposed research will increase understanding of the strategies diatoms use to sort particles. Our hypothesis is that in the process of understanding how these diatom surfaces control particles, blueprints for microfluidic devices will be identified. The appeal of diatoms goes beyond consideration of the geometrical patterning on their surfaces, because their frustules (the diatomic shells) are made primarily out of silica, a mater ....Nanoscale Particle Control by Rigid Biomineralised Surfaces. The proposed research will increase understanding of the strategies diatoms use to sort particles. Our hypothesis is that in the process of understanding how these diatom surfaces control particles, blueprints for microfluidic devices will be identified. The appeal of diatoms goes beyond consideration of the geometrical patterning on their surfaces, because their frustules (the diatomic shells) are made primarily out of silica, a material also used in nanofabrication. We expect that some of the strategies and patterns used by cells will be able to be directly transferred to microfluidics, and bypass years of empirical development in nanofabrication and lab-on-a-chip devices.Read moreRead less
Terahertz optoelectronics based on spintronics materials. Spintronic devices have many advantages which include non-volatility, permitting data retention in non-powered conditions, increased integration densities, high data processing speeds, low electrical energy demands, and a fabrication process compatible with those currently used in semiconductor microelectronics. The low energy consumption of spintronic devices also leads to economic and environmental benefits. Spintronic devices will help ....Terahertz optoelectronics based on spintronics materials. Spintronic devices have many advantages which include non-volatility, permitting data retention in non-powered conditions, increased integration densities, high data processing speeds, low electrical energy demands, and a fabrication process compatible with those currently used in semiconductor microelectronics. The low energy consumption of spintronic devices also leads to economic and environmental benefits. Spintronic devices will help to meet the sensing and storage demands of information technology in the decades to come. The project will enhance the international competitiveness and export power of Australian industry in the areas of information technology, quantum computing, magnetic recording and optoelectronics.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100146
Funder
Australian Research Council
Funding Amount
$800,000.00
Summary
Ultra high vacuum scanning probe microscope facility. Ultra high-vacuum scanning tunneling microscopy underpins advances in the understanding of novel materials for electronics, engineering and medical applications, including thin-films, nanostructures, advanced semiconductors, nanostructured (organic or inorganic) conductors, and nanoscale interfaces (heteronanostructures). It is a core technique underpinning the new Superscience agenda in Future Technologies. A number of present and future re ....Ultra high vacuum scanning probe microscope facility. Ultra high-vacuum scanning tunneling microscopy underpins advances in the understanding of novel materials for electronics, engineering and medical applications, including thin-films, nanostructures, advanced semiconductors, nanostructured (organic or inorganic) conductors, and nanoscale interfaces (heteronanostructures). It is a core technique underpinning the new Superscience agenda in Future Technologies. A number of present and future research fields will benefit from the presence of this instrument, which will enhance Australia's competitiveness in nanotechnology research and development. Training of PhD and graduate students in this area is essential to exploit the potentiality of nanotechnology for the future benefit of Australia.Read moreRead less