A miniaturised laser manipulator for ultra-precise and pain-free dentistry. This project aims to develop a miniaturized high-precision laser robotic device that can fit comfortably in the mouth to perform pain-free, vibration-free dental operations by utilising silicon-carbide on silicon technology to create a millimetre-sized two-axis controllable, highly-reflective mirror robust to high-power ultra-short laser pulses. This project expects to generate new knowledge in micro-mirror control using ....A miniaturised laser manipulator for ultra-precise and pain-free dentistry. This project aims to develop a miniaturized high-precision laser robotic device that can fit comfortably in the mouth to perform pain-free, vibration-free dental operations by utilising silicon-carbide on silicon technology to create a millimetre-sized two-axis controllable, highly-reflective mirror robust to high-power ultra-short laser pulses. This project expects to generate new knowledge in micro-mirror control using optically excited piezo-resistive sensors, and cold femtosecond laser ablation of hard dental tissue. Expected outcomes include a working prototype for laser removal of tooth materials at speeds exceeding dental drills, providing benefits in miniaturized laser devices and ultimately removing pain from dental procedures. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100060
Funder
Australian Research Council
Funding Amount
$638,853.00
Summary
High speed multi modal in-situ Transmission Electron Microscopy platform. This project aims to establish an in situ transmission electron microscope that will allow the atomic scale imaging of materials, while simultaneously measuring physical, chemical, electrical and optical properties, using a novel combination of cutting edge in-situ sample holders and an instrument mounted laser system. The instrument will be optimised for imaging of dynamic phenomena and the combination of spatial resoluti ....High speed multi modal in-situ Transmission Electron Microscopy platform. This project aims to establish an in situ transmission electron microscope that will allow the atomic scale imaging of materials, while simultaneously measuring physical, chemical, electrical and optical properties, using a novel combination of cutting edge in-situ sample holders and an instrument mounted laser system. The instrument will be optimised for imaging of dynamic phenomena and the combination of spatial resolution in the picometre scale, with microsecond level temporal resolution will be unique. The instrument will accelerate research into hydrogen production and carbon dioxide transformation, and thus support Australia's move to a more sustainable economy. Read moreRead less
Motion-adaptive PET technology for brain imaging of freely moving mice. This project aims to develop new brain imaging technology that adapts to and corrects for the motion of a responsive, freely moving mouse. Current technology requires the subject to be unconscious, precluding the use of imaging to study signalling pathways activated by external stimuli during cognitive and behavioural tasks. By harnessing new radiation detector, motion tracking and computational technologies, the project exp ....Motion-adaptive PET technology for brain imaging of freely moving mice. This project aims to develop new brain imaging technology that adapts to and corrects for the motion of a responsive, freely moving mouse. Current technology requires the subject to be unconscious, precluding the use of imaging to study signalling pathways activated by external stimuli during cognitive and behavioural tasks. By harnessing new radiation detector, motion tracking and computational technologies, the project expects to bridge this technology gap and provide significant technical and conceptual advances in the field. This will provide important benefits, such as equipping neuroscientists with new tools to answer fundamental questions about how the mammalian brain regulates behavioural adaptation to a changing environment.Read moreRead less
A New Nano Tip Fabrication Technique for Atomic Force Microscopy. This project aims to develop a new fabrication technique for high-aspect-ratio (long and sharp) tips for atomic force microscopy. The technique is expected to overcome the current fabrication limitation, that is fabricating one tip at a time which is unsuitable for batch fabrication. The proposed technique can be scaled up to mass produce nano tips. The technique is expected to create new commercial products and intellectual prope ....A New Nano Tip Fabrication Technique for Atomic Force Microscopy. This project aims to develop a new fabrication technique for high-aspect-ratio (long and sharp) tips for atomic force microscopy. The technique is expected to overcome the current fabrication limitation, that is fabricating one tip at a time which is unsuitable for batch fabrication. The proposed technique can be scaled up to mass produce nano tips. The technique is expected to create new commercial products and intellectual property. This innovation will lead to the emergence of breakthrough technologies in nanofabrication and nanomaterials synthesis. The benefits to Australia include new job opportunities and the development of local expertise in the field.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230100178
Funder
Australian Research Council
Funding Amount
$453,913.00
Summary
Fast, lightweight and live nanopore sequencing analysis. This project aims to address limitations in nanopore sequencing (latest emerging technology in genomics) by applying advanced computational methods. This project expects to create new knowledge in bioinformatics and computer science through innovative approaches that leverage the live data streaming capability of nanopore devices to deliver results rapidly, or in real-time. Expected outcomes include improved, highly efficient analysis meth ....Fast, lightweight and live nanopore sequencing analysis. This project aims to address limitations in nanopore sequencing (latest emerging technology in genomics) by applying advanced computational methods. This project expects to create new knowledge in bioinformatics and computer science through innovative approaches that leverage the live data streaming capability of nanopore devices to deliver results rapidly, or in real-time. Expected outcomes include improved, highly efficient analysis methods and designs for future creation of custom computer hardware for nanopore analysis. This will facilitate widespread adoption of nanopore technology in bioscience research and applied domains (health, agriculture, ecology, biosecurity and forensics), including for portable in-the-field applications. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100507
Funder
Australian Research Council
Funding Amount
$444,471.00
Summary
Integrated active microcantilevers for high-throughput nanometrology. This project aims to develop a new versatile, high-performance microsensor platform and microscopy method for measuring nano-scale structures. The proposed microscopy tool is expected to significantly increase imaging speed and miniaturize system footprint, thereby enabling high-throughput quality control of semiconductor devices. The expected outcome is a highly-scalable and low-cost imaging system that will close the technol ....Integrated active microcantilevers for high-throughput nanometrology. This project aims to develop a new versatile, high-performance microsensor platform and microscopy method for measuring nano-scale structures. The proposed microscopy tool is expected to significantly increase imaging speed and miniaturize system footprint, thereby enabling high-throughput quality control of semiconductor devices. The expected outcome is a highly-scalable and low-cost imaging system that will close the technology gap between fabrication and inspection at the nanoscale. The benefits to Australia should include the potential for commercialization to develop this next-generation microscopy tool in high-value market sectors.Read moreRead less
Noise-free Cryogenic Wavefront Sensing. This project aims to optimise the prototype adaptive optics technology for the Giant Magellan Telescope (GMT) by leveraging past investment in adaptive optics instrumentation and shortwave infrared detector systems. This project expects to generate significant improvements in GMT performance, with ten times greater image resolution than the Hubble Space Telescope and current estimates of >90% sky coverage, compared with ~50% coverage for current technology ....Noise-free Cryogenic Wavefront Sensing. This project aims to optimise the prototype adaptive optics technology for the Giant Magellan Telescope (GMT) by leveraging past investment in adaptive optics instrumentation and shortwave infrared detector systems. This project expects to generate significant improvements in GMT performance, with ten times greater image resolution than the Hubble Space Telescope and current estimates of >90% sky coverage, compared with ~50% coverage for current technology. Expected outcomes of this project include the development of a highly trained workforce and continued international collaboration in the field of high-technology sensor systems. This contribution to the GMT will provide significant benefits—it will change the way we view the Universe.Read moreRead less
3D integrated crystalline UV optical lens-fiber couplers for astronomy. This project aims to create micro-optics for astronomical and bio medical applications by 3D sculpturing them out of crystals by ultra-short pulse lasers. This project will introduce a new 3D fabrication approach of optical probes which have self-aligned micro-optical elements and optical fibres for a wide spectral range and with high quality optical surfaces. Expected outcomes of this project include building new capabiliti ....3D integrated crystalline UV optical lens-fiber couplers for astronomy. This project aims to create micro-optics for astronomical and bio medical applications by 3D sculpturing them out of crystals by ultra-short pulse lasers. This project will introduce a new 3D fabrication approach of optical probes which have self-aligned micro-optical elements and optical fibres for a wide spectral range and with high quality optical surfaces. Expected outcomes of this project include building new capabilities in micro-optical probes for industrial environments, establishing new solutions for international astronomy partners, and developing new techniques to image through optical fibres. This should provide significant benefits by improving astronomical instrumentation and also lead to less invasive endoscopy.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220101085
Funder
Australian Research Council
Funding Amount
$434,000.00
Summary
3D metafibre optics for advanced imaging. The aim is to design and interface multi-functional metasurfaces with optical fibres by using 3D laser printing technology. The anticipated goal is to develop innovative metafibres interfaced with achromatic meta-lenses, polarisation-selective metasurfaces, and Fourier-space imaging metasurfaces for all-on-fibre achromatic, full-Stokes polarimetric, and Fourier endoscopic imaging, respectively. Expected outcomes include new knowledge in fibre meta-optics ....3D metafibre optics for advanced imaging. The aim is to design and interface multi-functional metasurfaces with optical fibres by using 3D laser printing technology. The anticipated goal is to develop innovative metafibres interfaced with achromatic meta-lenses, polarisation-selective metasurfaces, and Fourier-space imaging metasurfaces for all-on-fibre achromatic, full-Stokes polarimetric, and Fourier endoscopic imaging, respectively. Expected outcomes include new knowledge in fibre meta-optics and a novel metafibre manufacturing platform in a critical sector of the 21st-century economy. The novel ultracompact, flexible, and versatile metafibre technology is expected to have a profound impact on fibre-optic imaging in photonic, biological, and telecommunications applications.Read moreRead less
Bioinks that Advance 3D bioprinting of cells to the 4th dimension. The aim of this research is to provide a simple method for creating complex 3D cell cultures for in vitro cell based assays using 3D printing. A versatile polymer system as a bioink made from entirely commercially available components, will be advanced that gives a full range of soft tissue mimics and which can be dynamically change on-demand after printing of the 3D cell cultures. The latter will provide in vitro mimics of in vi ....Bioinks that Advance 3D bioprinting of cells to the 4th dimension. The aim of this research is to provide a simple method for creating complex 3D cell cultures for in vitro cell based assays using 3D printing. A versatile polymer system as a bioink made from entirely commercially available components, will be advanced that gives a full range of soft tissue mimics and which can be dynamically change on-demand after printing of the 3D cell cultures. The latter will provide in vitro mimics of in vivo events never previously possible with more realistic models of what is found in vivo. Applications are in fundamental cell biology, studying diseases and developing new drugs. The outcomes from this research will be new knowledge on designing cheap extracellular matrix mimics and high throughout 3D cell assays.Read moreRead less