A gold-coated magnetic nanoparticle biosensor for detecting microRNA. The project aims to develop a biosensor for detecting short sequences of RNA, called microRNA (miRNA) in blood. There are about 100 miRNA sequences that are involved in most biological processes. Changes in the levels of some miRNA sequences can serve as a biomarker for many diseases including cancers. The miRNA will be detected using gold-coated magnetic nanoparticles modified with DNA sequences complementary to the miRNA of ....A gold-coated magnetic nanoparticle biosensor for detecting microRNA. The project aims to develop a biosensor for detecting short sequences of RNA, called microRNA (miRNA) in blood. There are about 100 miRNA sequences that are involved in most biological processes. Changes in the levels of some miRNA sequences can serve as a biomarker for many diseases including cancers. The miRNA will be detected using gold-coated magnetic nanoparticles modified with DNA sequences complementary to the miRNA of interest to capture the miRNA. Application of a magnetic field allows the levels of miRNA to be detected electrochemically. The expected outcome is a commercialisable biosensor for miRNA both as a diagnostic early detection device and a prognostic device for a range of miRNA biomarkers.Read moreRead less
Compact and versatile chip lasers for three-dimensional mine surveying. This project will bring together a world leading mine survey company, The University of Adelaide and Macquarie University researchers, to develop an 'eye-safe' micro laser for high resolution three-dimensional laser-mapping. The recently developed and patented 'chip' laser will allow the realisation of a compact, enhanced range laser-radar with unmatched resolution.
Foundation technology for quantum measurement, sensing and computing. This project will advance quantum control of cold ions, atoms and diamond colour centres for application of quantum science to high-tech problems, from ion-based quantum computing to diamond-based quantum imaging inside living cells.
Optical technology for quantum science. This project aims to develop and commercialise optical cavity and frequency stabilisation technology to generate laser light at new and precise wavelengths. Australia plays a leading role internationally in quantum science, a burgeoning area of research where fundamental quantum mechanical principles underpin exciting new technological applications, such as ion-based quantum computing, ultracold atom sensing for geo-exploration and defence, and nanoscale i ....Optical technology for quantum science. This project aims to develop and commercialise optical cavity and frequency stabilisation technology to generate laser light at new and precise wavelengths. Australia plays a leading role internationally in quantum science, a burgeoning area of research where fundamental quantum mechanical principles underpin exciting new technological applications, such as ion-based quantum computing, ultracold atom sensing for geo-exploration and defence, and nanoscale imaging inside living human cells. This project aims to continue and develop this role.Read moreRead less
Short-pulse laser cleaning for Australian heritage conservation. Conserving heritage objects is a demanding discipline, requiring a suite of techniques for different problems. Overseas, laser cleaning using long pulse techniques leaves microscopic damage as discrete chunks of material are removed, and is unsuitable for many materials. We have developed a short pulse laser process which can remove material molecule-by-molecule in a controlled fashion, and which can be readily halted once the fi ....Short-pulse laser cleaning for Australian heritage conservation. Conserving heritage objects is a demanding discipline, requiring a suite of techniques for different problems. Overseas, laser cleaning using long pulse techniques leaves microscopic damage as discrete chunks of material are removed, and is unsuitable for many materials. We have developed a short pulse laser process which can remove material molecule-by-molecule in a controlled fashion, and which can be readily halted once the final finish is achieved. We will research this technique for application to unique Australian heritage materials that are important to the specific conservation needs of the Australian War Memorial, the RAAF, Navy and Army Museums, Artlab Australia, and the Art Gallery of NSW.Read moreRead less