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Identifying Neuroanatomical Sub-phenotypes Of Schizophrenia
Funder
National Health and Medical Research Council
Funding Amount
$60,129.00
Summary
The clinical presentation of schizophrenia is varied across individuals, and has arguably hindered efforts to determine its cause/s. This project seeks to address this issue by investigating biological commonality in patients, to identify subgroups of schizophrenia patients with similar brain abnormalities, with the overall aim to examine cognitive and clinical characteristics and candidate genetic markers in association with biologically derived subtypes of schizophrenia.
Cognition In First Episode Psychosis: Mapping Relationships Between Task Performance, Brain Changes And Symptoms
Funder
National Health and Medical Research Council
Funding Amount
$79,734.00
Summary
Schizophrenia is a devastating illness. Medication can successfully treat the 'positive' symptoms, such as hallucinations and delusions. However, cognitive impairments have been identified as a greater burden. This project aims to better understand the brain basis of these cognitive impairments, by looking at the relationships between participants’ responses to cognitive tests, their brain activity during the testing, and their symptoms and general functioning over time.
Growth factors are essential molecules for normal brain development. Variations in the amount of the different growth factors have been implicated in such diseases as AlzheimerÍs and ParkinsonÍs disease. This project will study the precursor of a growth factor known as brain derived neurotrophic factor (BDNF) and what specific roles the precursor might play in brain development.
Exploring The Meaning And Experience Of Cardiovascular Health Of People Who Live With Severe And Persistent Mental Illness.
Funder
National Health and Medical Research Council
Funding Amount
$89,114.00
Summary
People with serious mental illness die up to 25 years before their peers, mostly from cardiovascular disease. Despite extensive research, we have made little impact on addressing this health inequity. By exploring the experience and meaning of personal cardiovascular health to people with severe mental illness, this study aims to generate new knowledge that will inform the tailoring of cardiovascular health promotion interventions that meet the unique requirements of this vulnerable population.