Fundamental flaws in the design and reporting of research outcomes can undermine evidence-based medicine, impede patient-centred care, cause harm to patients, and result in a waste of research dollars. Our 3-year multinational project engages with patients, caregivers, clinicians, researchers and policy makers, to establish core outcomes in haemodialysis. This will ensure that patient-centred outcomes are consistently measured and reported in haemodialysis trials and other forms of research.
Application Of Next Generation Sequencing For The Diagnosis Of Epileptic Encephalopathy: The Science, The Costings And The Impact.
Funder
National Health and Medical Research Council
Funding Amount
$122,714.00
Summary
Epileptic encephalopathy (EE) causes a devastating seizure disorder and intellectual disability in children. There are hundreds of rare, mostly genetic causes. Finding the cause is critical to guide treatment but currently investigations are expensive, invasive and rarely successful. This study aims to use the latest type of genetic testing to find the most cost and time effective way to diagnosis the most children, exploring the impact of testing on the child, family and health care services.
Patient-centred Volunteer Program For People With Dementia: A Stepped Wedge Cluster Randomised Controlled Trial Of The MyCare Ageing Program
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
The MyCare Ageing program provides hospitalised patients with dementia and/or delirium with tailored emotional and practical support via trained volunteers in hospital and in the transition home. This project will provide critical information on whether MyCare Ageing works to reduce future hospitalisations and prevent poor patient outcomes, the factors that impact on how the program is delivered in hospital and in the community, and whether the program is cost-effective.
Development And Clinical Evaluation Of A Depth Of Anaesthesia Monitor
Funder
National Health and Medical Research Council
Funding Amount
$424,785.00
Summary
Waking up during surgery (awareness under anaesthesia) is a frightening reality for some patients. Although uncommon (occurring in about 1 in 1000 operations), it remains one of the main concerns of patients before their surgery. Recent studies (including our own) have demonstrated that processed EEG monitoring using bispectral index (BIS) can markedly reduce the risk of awareness. Other EEG monitors are being developed, but each have weaknesses. As approximately two million Australians have a g ....Waking up during surgery (awareness under anaesthesia) is a frightening reality for some patients. Although uncommon (occurring in about 1 in 1000 operations), it remains one of the main concerns of patients before their surgery. Recent studies (including our own) have demonstrated that processed EEG monitoring using bispectral index (BIS) can markedly reduce the risk of awareness. Other EEG monitors are being developed, but each have weaknesses. As approximately two million Australians have a general anaesthetic each year, about 2000 will suffer an episode of awareness. More than 60 million people around the world have an anaesthetic, and so the problem is substantial. This suggests the potential benefits (health outcomes, commercial gains) are very great. In 2000 less than 5% of US hospitals used BIS monitoring; the current figure in the US is about 69% of the best-rated hospitals (US News and World Report) and 78% of teaching hospitals. A similar rapid growth is occurring in Australia and Europe. We are working with a successful Australian Company (Compumedics Ltd) to develop a better awareness monitor. We plan studies in groups of patients have surgery.Read moreRead less
Improving Access To Optimal Clinical Care For People With Chronic Hepatitis B Through The Implementation Of A Nurse-led Model Of Care
Funder
National Health and Medical Research Council
Funding Amount
$176,250.00
Summary
Chronic hepatitis B (CHB) is a global public health issue. Best practice guidelines indicate that early diagnosis and treatment can reduce mortality, however, guidelines are not being followed because uptake of management and treatment is low. This project aims to address the gap between optimal and current CHB management through implementation of a nursing service, which will build capacity, and target the need for improved management for this vulnerable group of patients.