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Research Topic : Satellite Communications
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    Molecular Mechanisms That Generate And Activate Muscle Stem Cells During Growth And Disease.

    Funder
    National Health and Medical Research Council
    Funding Amount
    $596,086.00
    Summary
    This study aims answer long standing questions in the field of muscle stem cells. Understanding how stem cell-driven muscle repair occurs has profound implications for our understanding of the pathology and treatment of muscle disease. Muscular dystrophies and myopathies are amongst the largest group of inherited disorders to afflict the human condition. It is our hope that the results of this research will lead to a better understanding of how treatments, stem cell based or otherwise, could be .... This study aims answer long standing questions in the field of muscle stem cells. Understanding how stem cell-driven muscle repair occurs has profound implications for our understanding of the pathology and treatment of muscle disease. Muscular dystrophies and myopathies are amongst the largest group of inherited disorders to afflict the human condition. It is our hope that the results of this research will lead to a better understanding of how treatments, stem cell based or otherwise, could be employed to correct such disorders.
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    Funded Activity

    Seeing Is Believing: Imaging Muscle Maintenance And Repair

    Funder
    National Health and Medical Research Council
    Funding Amount
    $727,191.00
    Summary
    We will characterise the behaviour of muscle stem cells in vivo within their micro-environment in normal and regenerating adult muscles, using high-end imaging technologies and mouse lines that we recently created. This will allow correlating cellular behaviours with the activation of signaling pathways, chosen for their likely role in the activation of satellite cells. We will then modulate the activity of these pathways in the satellite cell niche to evaluate their function.
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    Developing Evidence Based Strategies For Addressing Childhood Vaccination Rejection

    Funder
    National Health and Medical Research Council
    Funding Amount
    $743,927.00
    Summary
    Parental rejection of vaccines is a global concern that threatens to undermine disease control. A lack of evidence hampers the responses to this complex and persistent problem. We will interview parents who don’t vaccinate their children to learn what influences their decisions. We will then hold community juries and a public engagement process to refine strategies for responding to vaccination rejection that are acceptable to a well informed citizenry, practical and ethically justified.
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    Mobile Intervention For Drinking In Young People (MIDY): Randomised Controlled Trial

    Funder
    National Health and Medical Research Council
    Funding Amount
    $403,378.00
    Summary
    Binge drinking is a significant health and social issue in Australia. In this innovative trial, we will communicate with young people via their mobile phones while they are on a night out. Young people will send hourly information about their drinking and will receive a relevant message in response, encouraging them to slow down or avoid harmful activities. The methods and the messages were developed in partnership with young people and have been tested in real drinking situations.
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    Social Media To Enhance Indigenous Tobacco Control

    Funder
    National Health and Medical Research Council
    Funding Amount
    $922,680.00
    Summary
    Smoking prevalence among Aboriginal and Torres Strait Islander people is more than twice as high as the overall Australian population, and smoking is the leading cause of mortality and morbidity of Indigenous Australians. Accelerating the decline in smoking prevalence is an urgent priority to Close The Gap in health outcomes. The aim of this project is to understand how social media can be harnessed to enhance the impact of proven tobacco control strategies among Indigenous Australians.
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