Sympathetic Nervous System Regulation Of The Tumour Microenvironment
Funder
National Health and Medical Research Council
Funding Amount
$396,212.00
Summary
Metastasis is the major cause of morbidity and mortality in breast cancer. These studies will evaluate the translational opportunity of targeting the sympathetic nervous system as a common regulator of cancer progression pathways. By exploiting sensitive imaging technology for non-invasive, real-time assessment of stress biology, these studies will define the neuroendocrine mechanisms that operate in the tumour microenvironment to support dissemination and arrest of cancer cells in target organs ....Metastasis is the major cause of morbidity and mortality in breast cancer. These studies will evaluate the translational opportunity of targeting the sympathetic nervous system as a common regulator of cancer progression pathways. By exploiting sensitive imaging technology for non-invasive, real-time assessment of stress biology, these studies will define the neuroendocrine mechanisms that operate in the tumour microenvironment to support dissemination and arrest of cancer cells in target organs.Read moreRead less