A New Therapeutic Target For Stress-related Relapse
Funder
National Health and Medical Research Council
Funding Amount
$685,266.00
Summary
Relapse and hazardous drinking represent the most difficult clinical problems in treating patients with alcohol use disorders. We have identified a novel system in the brain for the regulation of stress-induced relapse. Successful completion of this project will indicate improved pharmacotherapeutic strategies for the treatment of alcoholism and drug abuse. Given the scale and costs of substance abuse disorders, improved therapeutic approaches will have immediate and sustained impact.
Evaluating The Anti-inflammatory, Anti-oxidant And Wound-healing Properties Of Australian Native Stingless Bee Cerumen From Trigona Carbonaria, And The Effects Of Bee Foraging Behaviours On Cerumen Bioactivity
Funder
National Health and Medical Research Council
Funding Amount
$95,313.00
Summary
I have a keen interest in evaluating the potential of natural products to promote wound-healing in humans. Cerumen, a resinous material produced by Australian native stingless bees, is easily obtained; however, the medicinal properties of this natural product have not been widely investigated. Therefore, the proposed PhD project aims to investigate the anti-inflammatory, anti-oxidant and wound-healing properties of Australian native stingless bee cerumen.
Are Novel Nitric Oxide Mimetics Protective In Vascular Disease?
Funder
National Health and Medical Research Council
Funding Amount
$634,044.00
Summary
Nitric oxide (NO) is a biologically active gas which controls blood flow and blood pressure. New drugs which mimic the effects of NO show promise in the treatment of cardiovascular disease. This study investigates the ability of NO mimetics to protect blood vessels in disease, by limiting the production of toxic molecules, improving blood flow and preventing blood clot formation. The information gained may lead to the development of new therapies for blood vessel diseases such as stroke.
Investigating A Novel Agent To Limit Brain Injury And Post-stroke Complications
Funder
National Health and Medical Research Council
Funding Amount
$412,429.00
Summary
Stroke is a leading cause of morbidity and mortality worldwide, but treatment options remain limited. The goal of this research project will be to examine the potential of new agent to protect the brain against stroke and to also treat complications that typically occur after stroke including infection and weight loss. It is anticipated that this project will ultimately lead to the development of an effective stroke therapy.