Slippery when wet: lubrication with responsive polymers. Lubrication and friction of aqueous (water-based) systems is important in many industrial and biological contexts, such as oil and gas exploration, solid/liquid separation, bioimplants and therapeutic treatments for joints. The outcomes of this project will provide greater control of friction through the use of stimulus responsive polymers.
Ageing and the muscle stem cell niche. Adult stem cells are critical for repair and maintenance of tissues and ageing tissues show reduced stem cell function. This project will focus on how ageing leads to disruption of communication between muscle stem cells and their niche. The project aims to identify new therapeutic targets for age-related muscle wasting and reduced mobility in the elderly.