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Scheme : Discovery Projects
Research Topic : SITE-SPECIFIC RECOMB
Australian State/Territory : NT
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  • Funded Activity

    Discovery Projects - Grant ID: DP0343672

    Funder
    Australian Research Council
    Funding Amount
    $290,000.00
    Summary
    Engineering and expression of recombinant antibodies that interact with plant pathogenic phytoplasma membrane proteins - a model for phytoplasma disease management. . In Australia phytoplasmas are associated with serious diseases including papaya dieback and strawberry lethal yellows. Phytoplasmas cannot be cultured so there is a paucity of knowledge at the genomic level. We have identified the ABC Transporter and FtsH genes and expressed these phytoplasma membrane proteins (MP) in E. coli . We .... Engineering and expression of recombinant antibodies that interact with plant pathogenic phytoplasma membrane proteins - a model for phytoplasma disease management. . In Australia phytoplasmas are associated with serious diseases including papaya dieback and strawberry lethal yellows. Phytoplasmas cannot be cultured so there is a paucity of knowledge at the genomic level. We have identified the ABC Transporter and FtsH genes and expressed these phytoplasma membrane proteins (MP) in E. coli . We will generate antibody fragments that bind these MP and express them in tomato. We will analyse antibody expression in tomato and study their association with the phytoplasma membrane. Transgenic plants will be inoculated with phytoplasma and monitored for resistance. This work represents a major step towards engineering resistance to phytoplasmas.
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    Active Funded Activity

    Discovery Projects - Grant ID: DP210103446

    Funder
    Australian Research Council
    Funding Amount
    $268,184.00
    Summary
    Mothers' little helper: Alcohol use in working mothers. This project aims to generate unique insights into the strains that Australian working mothers face in their daily lives and the impact these strains have on their alcohol consumption. Using innovative methods to understand strains resulting from two major life domains, family and work, the project expects to generate new knowledge which can be used to develop interventions to address this important issue. The results of this study can prov .... Mothers' little helper: Alcohol use in working mothers. This project aims to generate unique insights into the strains that Australian working mothers face in their daily lives and the impact these strains have on their alcohol consumption. Using innovative methods to understand strains resulting from two major life domains, family and work, the project expects to generate new knowledge which can be used to develop interventions to address this important issue. The results of this study can provide significant benefits not only to the quality of life of working mothers in Australia but also has society-wide implications. This is due to alcohol use being a leading avoidable cause for productivity loss alongside other social, community and economic costs.
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