Pathogen recognition and plant-defence activation by a novel Fusarium wilt-resistance protein from tomato. The devastating effects of Fusarium wilt disease of tomato is a threat to one of Australia's most economically important horticultural crops. Resistant tomato varieties offer the most effective means of control but the fundamental mechanisms underlying this resistance are yet to be understood. This research will increase our understanding of resistance to Fusarium wilt disease. The knowledg ....Pathogen recognition and plant-defence activation by a novel Fusarium wilt-resistance protein from tomato. The devastating effects of Fusarium wilt disease of tomato is a threat to one of Australia's most economically important horticultural crops. Resistant tomato varieties offer the most effective means of control but the fundamental mechanisms underlying this resistance are yet to be understood. This research will increase our understanding of resistance to Fusarium wilt disease. The knowledge gained will assist in the development of new robust, sustainable approaches to disease control, as well as the development of pre-emptive strategies to avert major outbreaks, which will ensure reliable productivity and minimal economic losses into the future.Read moreRead less
Translocation of secreted effector proteins from fungal pathogens into host plant cells. Every year, fungal diseases of plants cause huge losses in agricultural productivity and extensive environmental damage in Australia. Disease control in major crops, like wheat, currently relies heavily on breeding for disease resistance. However, fungal pathogens continually adapt to overcome plant defences, necessitating identification of new sources of resistance. The research in this project will eluc ....Translocation of secreted effector proteins from fungal pathogens into host plant cells. Every year, fungal diseases of plants cause huge losses in agricultural productivity and extensive environmental damage in Australia. Disease control in major crops, like wheat, currently relies heavily on breeding for disease resistance. However, fungal pathogens continually adapt to overcome plant defences, necessitating identification of new sources of resistance. The research in this project will elucidate the molecular basis of a new aspect of the establishment of plant infection by fungi, and in so doing will provide new avenues for the development of novel disease resistance strategies, with relevance in particular to devastating cereal diseases like wheat rust.Read moreRead less
Role of fungal secreted proteins as plant disease effectors. Many crop diseases are economically significant threats to agricultural productivity in Australia, with rust fungi in particular being a major problem for cereal grain production. Current methods of rust disease control are based on breeding for resistance but continued adaption by rust fungi to overcome plant defences means there is an urgent need for new methods of crop protection. This project will investigate molecular processes ....Role of fungal secreted proteins as plant disease effectors. Many crop diseases are economically significant threats to agricultural productivity in Australia, with rust fungi in particular being a major problem for cereal grain production. Current methods of rust disease control are based on breeding for resistance but continued adaption by rust fungi to overcome plant defences means there is an urgent need for new methods of crop protection. This project will investigate molecular processes underlying fungal infection of plants, focusing on mechanisms that enable fungi to take over the metabolism of infected cells. The research will provide basic knowledge for development of novel and durable disease resistance strategies.Read moreRead less
Design of Multi-Gigabit Millimeter Wave Cellular Networks. It has been predicted that within the next ten years trillions of devices will connect to cellular networks and cause a thousand-fold increase in mobile traffic. This will lead to a severe spectrum shortage and congested cellular networks. Large expanses of the millimetre-wave spectrum have the potential to meet the capacity demands of future cellular networks. The project aims to develop the fundamental sciences for millimetre-wave cell ....Design of Multi-Gigabit Millimeter Wave Cellular Networks. It has been predicted that within the next ten years trillions of devices will connect to cellular networks and cause a thousand-fold increase in mobile traffic. This will lead to a severe spectrum shortage and congested cellular networks. Large expanses of the millimetre-wave spectrum have the potential to meet the capacity demands of future cellular networks. The project aims to develop the fundamental sciences for millimetre-wave cellular communications, which thought to be essential for the design of next generation cellular networks with data rates at least three orders of magnitude faster than those in current cellular networks. The research outcomes are expected to provide the foundations and tools for building a future mobile broadband network infrastructure in Australia.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100157
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
Confocal and single molecule microscopes for systems microscopy. This project aims to establish Australia’s first system microscopy facility with dedicated live-cell confocal and single-molecule fluorescence microscopes. In systems microscopy, the imaging workflow is automated so that large and unbiased data sets of the spatiotemporal organisation of molecules and cells can be generated. Combined with statistical and bioinformatics analyses, image-derived data provides system-wide information th ....Confocal and single molecule microscopes for systems microscopy. This project aims to establish Australia’s first system microscopy facility with dedicated live-cell confocal and single-molecule fluorescence microscopes. In systems microscopy, the imaging workflow is automated so that large and unbiased data sets of the spatiotemporal organisation of molecules and cells can be generated. Combined with statistical and bioinformatics analyses, image-derived data provides system-wide information that is not easily obtainable with other approaches. The project will enable Australian researchers to image and analyse the full complexity of biological systems, potentially transforming cell biology, drug development and understanding the molecular basis of disease. It will also demonstrate how the capacity of microscopy facilities can be enhanced and bias in imaging data reduced by automating data acquisition and mining of image-based data.Read moreRead less
Active Sound Control and Noise Cancellation over Space. This project aims to address the critical issues for creating acoustic quiet zones in a noisy environment. It will provide novel signal processing theory for further development of active noise cancellation techniques over spatial regions. New technologies developed from this project are expected to underpin the future development of acoustic signal processing research and will have a broad range of applications such as reduction of noise i ....Active Sound Control and Noise Cancellation over Space. This project aims to address the critical issues for creating acoustic quiet zones in a noisy environment. It will provide novel signal processing theory for further development of active noise cancellation techniques over spatial regions. New technologies developed from this project are expected to underpin the future development of acoustic signal processing research and will have a broad range of applications such as reduction of noise inside cars, creation of individual quiet zones in passenger planes and mitigation of acoustic noise made by industrial plants to neighbouring suburbs. The outcomes from this proposal will also have economic importance as it can reduce the health risk posed to people working or living in noisy environments.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE150100363
Funder
Australian Research Council
Funding Amount
$330,000.00
Summary
The cocktail party problem: Advancing binaural localisation techniques. This project aims to advance fundamental research in source localisation by using a binaural system with two sensors to mimic human listening capabilities. It will provide new theory of source localisation features, novel signal processing techniques and design of binaural devices for localising sound sources in a cluttered acoustic environment. New technologies developed from this project will endeavour to lead to further d ....The cocktail party problem: Advancing binaural localisation techniques. This project aims to advance fundamental research in source localisation by using a binaural system with two sensors to mimic human listening capabilities. It will provide new theory of source localisation features, novel signal processing techniques and design of binaural devices for localising sound sources in a cluttered acoustic environment. New technologies developed from this project will endeavour to lead to further development of binaural audio research and will have a broad range of applications, such as hearing aids, personal sound amplification products and humanoid robots. The project aims to enable people wearing binaural devices or robots having two artificial ears to localise sounds and to follow a conversation in realistic situations.Read moreRead less
Nonlinear Signal Processing: Optimisation and Tracking on Manifolds. Most hi-tech electronic devices must process signals. A mobile phone, for example, must encode, transmit, decode and receive voice signals. This project will use specialised mathematical theories applied in novel ways to advance the theoretical foundations of signal processing and develop better signal processing algorithms for practical applications. Companies with access to better signal processing algorithms have an edge ov ....Nonlinear Signal Processing: Optimisation and Tracking on Manifolds. Most hi-tech electronic devices must process signals. A mobile phone, for example, must encode, transmit, decode and receive voice signals. This project will use specialised mathematical theories applied in novel ways to advance the theoretical foundations of signal processing and develop better signal processing algorithms for practical applications. Companies with access to better signal processing algorithms have an edge over their competitors, and consumers benefit too from better and more advanced products.Read moreRead less
Only recently has it emerged that our cells have a built-in backup mechanism that instructs cells to die in extreme cases, such as when viruses have hijacked a cell. A misfiring backup mechanism is thought to underlie a number of human diseases, including inflammatory disease. Our investigation will establish a starting point for the development of novel anti-inflammatory drugs.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775621
Funder
Australian Research Council
Funding Amount
$494,000.00
Summary
Mileura Widefield Array: A New Low Frequency Telescope. A new radio-quiet site for international radio astronomy is being developed at Mileura in Western Australia. We have constructed a low frequency test array on the site, and established that the site is excellent for radio astronomy. We plan to build a telescope which will observe the early universe, when stars and galaxies where first born. This will be the first telescope capable of this type of measurement of the early universe. In addi ....Mileura Widefield Array: A New Low Frequency Telescope. A new radio-quiet site for international radio astronomy is being developed at Mileura in Western Australia. We have constructed a low frequency test array on the site, and established that the site is excellent for radio astronomy. We plan to build a telescope which will observe the early universe, when stars and galaxies where first born. This will be the first telescope capable of this type of measurement of the early universe. In addition, the telescope will measure the solar wind, and its potential interactions with the earth.
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