Raising the Internet's Quality of Service through improved congestion management. This project aims to develop methods for improving the service quality of the internet by better management of congestion. Improved service quality will be evident to internet users in the form of reduced delay and data loss. The proposed research is significant because as well as improving service quality, it will facilitate delivery of internet services over poor quality communications infrastructure such as is p ....Raising the Internet's Quality of Service through improved congestion management. This project aims to develop methods for improving the service quality of the internet by better management of congestion. Improved service quality will be evident to internet users in the form of reduced delay and data loss. The proposed research is significant because as well as improving service quality, it will facilitate delivery of internet services over poor quality communications infrastructure such as is present in many remote and regional areas of Australia. It also will result in more efficient utilisation of telecommunications infrastructure. The project will deliver implementations in the form of software which is easily installed in any computer.Read moreRead less
A fundamental study of the role of signal transduction pathways in the regulation of Chlamydia's complex developmental cycle. Chlamydia are unique organisms in the microbial world. They are among the smallest bacteria and yet have a complex two-stage developmental cycle. In addition they are major causes of disease in animals and humans with no vaccines available. We have used the recent flood of full genome sequence data to identify over 30 new cell signalling proteins. By understanding how the ....A fundamental study of the role of signal transduction pathways in the regulation of Chlamydia's complex developmental cycle. Chlamydia are unique organisms in the microbial world. They are among the smallest bacteria and yet have a complex two-stage developmental cycle. In addition they are major causes of disease in animals and humans with no vaccines available. We have used the recent flood of full genome sequence data to identify over 30 new cell signalling proteins. By understanding how these cell signaling proteins are organized into pathways and how this microorganism controls its complex growth and developmental cycle, we will be able to develop novel methods of control. We are at the fore front of international research and therefore uniquely placed to conduct this project.Read moreRead less
Resource-aware Signal Processing and Control Algorithms for Networked Sensor Systems. Networked sensing and control is an important technology for Australia's future. Applications range from monitoring wildlife habitats to safety management of large civil structures. This project will lead to sustainable engineering solutions for these applications and provide key fundamental performance limits. Beyond the creation of new theory and algorithms, the national and community benefits will include: ....Resource-aware Signal Processing and Control Algorithms for Networked Sensor Systems. Networked sensing and control is an important technology for Australia's future. Applications range from monitoring wildlife habitats to safety management of large civil structures. This project will lead to sustainable engineering solutions for these applications and provide key fundamental performance limits. Beyond the creation of new theory and algorithms, the national and community benefits will include: (i) enhancement of Australia's reputation for innovative Engineering research through quality publications and international collaborations; and (ii) improvement of the research and development capability in the ICT sector through rigorous training of postgraduate students and postdoctoral fellows.Read moreRead less
Joint modelling and recognition of linguistic and paralinguistic speech information. A new modelling framework will be developed exploiting interdependence between linguistic and paralinguistic cues to improve automatic recognition of emotion-related information. Applications in the high-tech industry include automatic routing of angry telephone customers or pre-suicidal crisis centre callers to specialist operators/clinicians.
Modelling and estimation methods for discrete multi-dimensional systems. Multi-dimensional signal processing plays a role in a variety of application areas, ranging from remote sensing for environmental monitoring and geological mapping, to medical imaging and the automatic control of industrial processes. The success of the project will provide mathematical tools for the advancement of the state-of-the-art in these broad areas.
A study of the nongenomic action of Vitamin D: proposed role of the nuclear VDR and downstream signalling molecules. Vitamin D (1,25D) activates genes in the nucleus through the vitamin D receptor (VDR). 1,25D can also elicit rapid responses at the plasma membrane. This action is critical to the activation of nuclear genes. We hypothesise that a proportion of the nuclear VDR is located at the plasma membrane where it stimulates downstream signalling molecules eg Ras, ERK1/2 and ERK5. We plan to ....A study of the nongenomic action of Vitamin D: proposed role of the nuclear VDR and downstream signalling molecules. Vitamin D (1,25D) activates genes in the nucleus through the vitamin D receptor (VDR). 1,25D can also elicit rapid responses at the plasma membrane. This action is critical to the activation of nuclear genes. We hypothesise that a proportion of the nuclear VDR is located at the plasma membrane where it stimulates downstream signalling molecules eg Ras, ERK1/2 and ERK5. We plan to explore this hypothesis and to identify the signalling molecules. We will also investigate our novel finding that a specific Ras isoform is involved in ERK5 activation. The work will provide new information on signalling pathways.Read moreRead less
Modelling, Analysis and Synthesis Tools for Multi-Dimensional Signal Processing Systems. Multi-dimensional signal processing plays a role in a variety of application areas, ranging from remote sensing for environmental monitoring and geological mapping, to medical imaging and the automatic control of industrial processes. The success of this project will provide mathematical tools for the advancement of the state-of-the-art in these broad areas.
A unified framework for analyzing the timescale of interest for traffic measurements, modelling and performance analysis. The revenue generated from traditional telecommunication services is continuing to drop. New value-added services such as multimedia services become the fastest growing revenue-generating sector in Australia's telecommunications industry. The ubiquitous presence of scaling behaviour in network traffic presents a big challenge for delivering better Quality-of-Service (QoS) whi ....A unified framework for analyzing the timescale of interest for traffic measurements, modelling and performance analysis. The revenue generated from traditional telecommunication services is continuing to drop. New value-added services such as multimedia services become the fastest growing revenue-generating sector in Australia's telecommunications industry. The ubiquitous presence of scaling behaviour in network traffic presents a big challenge for delivering better Quality-of-Service (QoS) which is demanded by the new services. A complete understanding of the scaling behaviour and its impact is very important. This research addresses a key problem of defining the timescale range of interest for the scaling behaviour. The research outcome benefits a number of areas, which are all critical for developing enhanced QoS support and better network management.Read moreRead less
Spectral analysis with selective harmonic emphasis. This project lies under ARC research priority area "Frontier Technologies for Building and Transforming Australian Industries". The signal processing algorithms to be developed in this project will be useful in many important practical applications, which include various bio-medical imaging modalities, beamforming, radar, sonar and target tracking using sensor arrays. The idea is to use the prior knowledge to enhance certain desired properties ....Spectral analysis with selective harmonic emphasis. This project lies under ARC research priority area "Frontier Technologies for Building and Transforming Australian Industries". The signal processing algorithms to be developed in this project will be useful in many important practical applications, which include various bio-medical imaging modalities, beamforming, radar, sonar and target tracking using sensor arrays. The idea is to use the prior knowledge to enhance certain desired properties of the algorithms via intelligent processing. In this light the project also lies within the ARC research priority area of "Smart Information use".Read moreRead less
Structural studies on the mitochondrial protein import machinery. Proteins transported across biological membranes are generally synthesized as precursors with signal sequences. These signal sequences are decoded by one of a number of membrane-specific protein transport machinery, but how this decoding occurs is largely unknown. This proposal aims to understand the structural basis of protein import into the mitochondrion, a poorly understood biological process. This study will enhance signif ....Structural studies on the mitochondrial protein import machinery. Proteins transported across biological membranes are generally synthesized as precursors with signal sequences. These signal sequences are decoded by one of a number of membrane-specific protein transport machinery, but how this decoding occurs is largely unknown. This proposal aims to understand the structural basis of protein import into the mitochondrion, a poorly understood biological process. This study will enhance significantly our understanding of mitochondrial biology, and will also have ramifications for other areas of protein transport.Read moreRead less