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Current Selection
Scheme : NHMRC Project Grants
Research Topic : SEXUAL MATURATION
Status : Closed
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  • Funded Activity

    Risk Factors For Upper Limb Fractures In Adolescence

    Funder
    National Health and Medical Research Council
    Funding Amount
    $165,040.00
    More information
    Funded Activity

    The Contribution Of Sexual Experiences, Abuse, Dysfunction And Satisfaction To Health And Well Being

    Funder
    National Health and Medical Research Council
    Funding Amount
    $200,239.00
    More information
    Funded Activity

    Maturation Of Eggs And Sperm For Treatment Of Human Inf Ertility

    Funder
    National Health and Medical Research Council
    Funding Amount
    $203,100.00
    More information
    Funded Activity

    The Australian Longitudinal Study Of Health And Relationships

    Funder
    National Health and Medical Research Council
    Funding Amount
    $2,292,187.00
    Summary
    Achieving satisfaction in our intimate relationships is a vital component of our well being. To date, most studies of sexual and reproductive health have focused on how common particular problems might be. Thus, studies have tended to have relatively narrow focuses on, for example, the prevalence of pregnancy, miscarriage and termination, or on patterns of sexual practice and contraceptive use, or on the frequency with which individuals experience sexual difficulties. Yet, all of these are inter .... Achieving satisfaction in our intimate relationships is a vital component of our well being. To date, most studies of sexual and reproductive health have focused on how common particular problems might be. Thus, studies have tended to have relatively narrow focuses on, for example, the prevalence of pregnancy, miscarriage and termination, or on patterns of sexual practice and contraceptive use, or on the frequency with which individuals experience sexual difficulties. Yet, all of these are inter-related aspects of sexual and reproductive health that can have profound impacts on each other. Importantly, most of these studies have looked at these issues at a single point in time and could only infer the likely contribution of prior events on currently observed patterns. This study will recruit a random sample of Australians aged 16 to 65 years and interview them annually, initially over a four-year period. It will collect detailed information about sexual and reproductive health and provide essential information about how sexual and reproductive health changes as we age. It will document the relationships between patterns of sexual behaviour, contraceptive choices, pregnancy and its outcomes, and sexual functioning including the experience of sexual problems and the achievement of satisfaction in our physical and emotional intimate relationships.
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    Funded Activity

    The Australian Longitudinal Study Of Health And Relationships

    Funder
    National Health and Medical Research Council
    Funding Amount
    $1,624,798.00
    Summary
    Ensuring the sexual and reproductive health of the Australian population is essential for our wellbeing as a nation. As well as the overall importance, at least three aspects of sexual and reproductive health are among the key policy issues for present Australian governments: maintaining and increasing the birth rate; reducing the abortion rate; and preventing and controlling Chlamydia infections.
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    Funded Activity

    Characterisation Of Cumulus Cell Molecular Mediators Of Oocyte Health

    Funder
    National Health and Medical Research Council
    Funding Amount
    $451,896.00
    Summary
    Many women are poorly fertile because of poor egg quality due to age, disease and lifestyle. IVF can assist, but requires large doses of hormone, which can lead to significant health risks. IVM is an alternative lab technique to IVF, but has very poor success. We discovered that synthetic proteins copied from recently discovered egg proteins can be added to the egg and substantially increase IVM success. Answering why will further will aid treatment for infertile women
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    Funded Activity

    Transdermal Testosterone Therapy: A Potential Treatment For Selective Serotonin Reuptake Inhibitor (SSRI)-associated Sexual Dysfunction In Women

    Funder
    National Health and Medical Research Council
    Funding Amount
    $241,351.00
    Summary
    Female sexual dysfunction (FSD) is frequently reported with selective serotonin reuptake inhibitor (SSRI) therapy and venlafaxine, these being the most common antidepressants used by Australian women. We have shown that testosterone therapy significantly improves sexual function in women with FSD. However SSRI-users have been excluded from these past studies. The aim of this study is to assess the efficacy of transdermal testosterone therapy for treatment of sexual dysfunction associated with SS .... Female sexual dysfunction (FSD) is frequently reported with selective serotonin reuptake inhibitor (SSRI) therapy and venlafaxine, these being the most common antidepressants used by Australian women. We have shown that testosterone therapy significantly improves sexual function in women with FSD. However SSRI-users have been excluded from these past studies. The aim of this study is to assess the efficacy of transdermal testosterone therapy for treatment of sexual dysfunction associated with SSRI therapy.
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    Funded Activity

    Long Term Consequences Of Repeated Prenatal Corticosteroids In Sheep

    Funder
    National Health and Medical Research Council
    Funding Amount
    $252,904.00
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    Funded Activity

    Molecules Responsible For The Maturation Of Nerve Cells

    Funder
    National Health and Medical Research Council
    Funding Amount
    $283,590.00
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    Funded Activity

    MicroRNA Regulation Of Sex Determination And Gonad Development.

    Funder
    National Health and Medical Research Council
    Funding Amount
    $518,076.00
    Summary
    Sex determination, the decision to develop into either boy or girl, influences most aspects of our lives. Consequently, disorders of sexual development (~1% of births), resulting in genital abnormalities, infertility and often cancer, are extremely traumatic for the individual. The molecular basis of these disorders is not well understood. This project will identify new factors important for sex determination and therefore will improve diagnosis and clinical care for the patients.
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