Supercritical-microfluidics technology for targeted delivery to the colon. This research will develop nanosystems to target delivery of drugs to the colon. Our nanosystems will permit the combination of clinically used chemotherapy drugs within a single dosage form. This will improve the efficiency of delivery to the colon while reducing unwanted side-effects. A novel supercritical microfluidics system will be developed to produce therapeutic nano-carriers in a continuous mode with lower labour ....Supercritical-microfluidics technology for targeted delivery to the colon. This research will develop nanosystems to target delivery of drugs to the colon. Our nanosystems will permit the combination of clinically used chemotherapy drugs within a single dosage form. This will improve the efficiency of delivery to the colon while reducing unwanted side-effects. A novel supercritical microfluidics system will be developed to produce therapeutic nano-carriers in a continuous mode with lower labour requirement, higher production rate and better quality control than conventional production methods. The new process will combine benefits from both supercritical fluid technology (green process) and microfluidics (high mass & heat transfer).Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220101043
Funder
Australian Research Council
Funding Amount
$413,482.00
Summary
Peculiar membrane structures for removing microplastics from water. Microplastic pollution can inflict irreparable damage to human health and the environment. This project aims to develop functional membrane structures specifically designed to remove microplastics from aquatic and wastewater treatment systems. The approach will utilise advanced techniques in material science, separation science and fluid mechanics. The expected outcomes include advanced membranes with high separation efficiency ....Peculiar membrane structures for removing microplastics from water. Microplastic pollution can inflict irreparable damage to human health and the environment. This project aims to develop functional membrane structures specifically designed to remove microplastics from aquatic and wastewater treatment systems. The approach will utilise advanced techniques in material science, separation science and fluid mechanics. The expected outcomes include advanced membranes with high separation efficiency for microplastics filtration. This will have significant benefits, including the efficient removal of microplastics from water sources securing cleaner potable, irrigation and recycled water, and contributing to a safer, healthier environment for all Australians.Read moreRead less
Novel disinfection to combat antibiotic resistance . Control of antimicrobial resistance in water is critical. Disinfection in water and wastewater treatment plants is a vital barrier against antibiotic resistant bacteria (ARB); however, it is less effective in controlling- and may even facilitate the spread of antibiotic resistance genes (ARGs). This project aims to comprehensively investigate the effectiveness of widely-used disinfection processes in controlling ARB/ARGs, determine the underly ....Novel disinfection to combat antibiotic resistance . Control of antimicrobial resistance in water is critical. Disinfection in water and wastewater treatment plants is a vital barrier against antibiotic resistant bacteria (ARB); however, it is less effective in controlling- and may even facilitate the spread of antibiotic resistance genes (ARGs). This project aims to comprehensively investigate the effectiveness of widely-used disinfection processes in controlling ARB/ARGs, determine the underlying mechanisms, and identify optimal treatment conditions. This project also aims to develop a novel, cost-effective and environmentally friendly disinfection process for efficient ARGs destruction, thus significantly strengthening Australia’s capacity to prevent the spread of antibiotic resistance.Read moreRead less
Unlocking Australia's offshore gas endowment. This project aims to develop practical new methods of predicting and detecting the formation of solids in gas and liquefied natural gas (LNG) production. Australia has large offshore reserves of natural gas and has made the investments necessary to help fuel the global transition to cleaner, reliable energy sources. However, conventional engineering approaches of producing gas from deep-water reserves have reached the limits of viability because of t ....Unlocking Australia's offshore gas endowment. This project aims to develop practical new methods of predicting and detecting the formation of solids in gas and liquefied natural gas (LNG) production. Australia has large offshore reserves of natural gas and has made the investments necessary to help fuel the global transition to cleaner, reliable energy sources. However, conventional engineering approaches of producing gas from deep-water reserves have reached the limits of viability because of the costs required to prevent solids forming in subsea pipelines or cryogenic LNG plants. The project’s expected outcome include sophisticated tools in open-access software based on these new predictive methods, and a step-change in Australia’s ability to access its offshore gas.Read moreRead less
Design a Targeted Delivery System for Probiotics. The project aims to improve the effectiveness of probiotics by developing a targeted delivery system to the colon. This interdisciplinary research will generate new knowledge in the field of microbiota and develop new delivery systems for live microorganisms and other active compounds. Expected outcomes include increased understanding of the factors affecting the viability of probiotics during storage and passage through the gastro-intestinal tra ....Design a Targeted Delivery System for Probiotics. The project aims to improve the effectiveness of probiotics by developing a targeted delivery system to the colon. This interdisciplinary research will generate new knowledge in the field of microbiota and develop new delivery systems for live microorganisms and other active compounds. Expected outcomes include increased understanding of the factors affecting the viability of probiotics during storage and passage through the gastro-intestinal tract, the establishment of probiotics into gut flora, and how this incorporation affects the dynamics of gut microbiota. The new technology can be utilised across a wide range of therapeutics that target the colon to promote the well-being of our society through commercialisation by industry partner.Read moreRead less
Model studies of Australian lump ore applied to blast furnace ironmaking. Ore lump use in ironmaking blast furnaces (BFs) requires no preprocessing and has a lower carbon footprint. However, it suffers various technical problems. This project aims to understand and optimize the conditions for such operations. This will be achieved by means of a combined theoretical and experimental program, involving the use of state-of-the-art multiscale computer modelling and simulation techniques. The researc ....Model studies of Australian lump ore applied to blast furnace ironmaking. Ore lump use in ironmaking blast furnaces (BFs) requires no preprocessing and has a lower carbon footprint. However, it suffers various technical problems. This project aims to understand and optimize the conditions for such operations. This will be achieved by means of a combined theoretical and experimental program, involving the use of state-of-the-art multiscale computer modelling and simulation techniques. The research outcomes will be tested in the design and control of lump charging operations in practice through collaboration with the industrial partner. This will ultimately increase Australian ore lump usage in BFs, leading to significant financial and environmental benefits to Australia and the entire steel industry worldwide.Read moreRead less
Towards New Functionality in Dairy Ingredients. The Australian dairy industry plays a significant part in the nation’s economy, with almost $3 billion in export revenue in 2016-2017. Powdered dairy products extend shelf life and ease of transport, with >20% annual growth in premium products, such as milk protein concentrates and infant formula powders. This project aims to support the development of value-added dairy powders by investigating the impact of a novel high pressure processing technol ....Towards New Functionality in Dairy Ingredients. The Australian dairy industry plays a significant part in the nation’s economy, with almost $3 billion in export revenue in 2016-2017. Powdered dairy products extend shelf life and ease of transport, with >20% annual growth in premium products, such as milk protein concentrates and infant formula powders. This project aims to support the development of value-added dairy powders by investigating the impact of a novel high pressure processing technology in enhancing the properties of dairy powders and/or introducing new functionality. Successful outcomes will help expand the offering of high value dairy ingredients and thus increase the global competitiveness of Australian dairy manufacturing.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH170100009
Funder
Australian Research Council
Funding Amount
$4,000,000.00
Summary
ARC Research Hub for Energy-efficient Separation. The ARC Research Hub for Energy-efficient Separation aims to develop advanced separation materials, innovative products and smart processes to reduce the energy consumption of separation processes. The Research Hub will create a multi-disciplinary training platform, supplying a highly-trained workforce for the advanced manufacturing sector, particularly in separation technology–a growth area in which Australia can lead the world. The advancement ....ARC Research Hub for Energy-efficient Separation. The ARC Research Hub for Energy-efficient Separation aims to develop advanced separation materials, innovative products and smart processes to reduce the energy consumption of separation processes. The Research Hub will create a multi-disciplinary training platform, supplying a highly-trained workforce for the advanced manufacturing sector, particularly in separation technology–a growth area in which Australia can lead the world. The advancement of Australia’s capability as a world-leading technology provider in manufacturing advanced separation materials and equipment will enable Australian industry to become more energy-efficient and cost-competitive in a global economy.Read moreRead less
Next generation gas separations via innovative adsorption technologies. This project aims to develop new gas separation technologies that combine novel materials and pressure swing adsorption cycles to deliver inexpensive industrial processes capable of both high recovery and high purity products. The project will advance our ability to manipulate the phenomenon of regulated guest admission into microporous materials, and integrate such materials within new types of dual-reflux adsorption cycles ....Next generation gas separations via innovative adsorption technologies. This project aims to develop new gas separation technologies that combine novel materials and pressure swing adsorption cycles to deliver inexpensive industrial processes capable of both high recovery and high purity products. The project will advance our ability to manipulate the phenomenon of regulated guest admission into microporous materials, and integrate such materials within new types of dual-reflux adsorption cycles that deliver multiple refined gas products. Successful implementation of these industrial developments will increase Australia's access to cheap supplies of natural gas, encourage the broader use of biomass, lower the carbon emissions of industrial processes, and efficiently recover high-value compounds only present at trace concentrations.Read moreRead less
Data-based Control of Process Feature Dynamics through Latent Behaviours. This project aims to develop a novel data-based approach to control the feature dynamics of complex industrial processes. The dynamic features of desired process operations (leading to high energy and material efficiencies and good product quality) are often not directly measured but can be distilled from high-dimensional big process data. However, little effort has been made to develop process control approaches to achiev ....Data-based Control of Process Feature Dynamics through Latent Behaviours. This project aims to develop a novel data-based approach to control the feature dynamics of complex industrial processes. The dynamic features of desired process operations (leading to high energy and material efficiencies and good product quality) are often not directly measured but can be distilled from high-dimensional big process data. However, little effort has been made to develop process control approaches to achieve desired dynamic features. This project aims to develop such a data-based approach by controlling latent variable dynamics, using the behavioural systems framework integrated with big data analytics and artificial neural networks. The outcomes are expected to help build a cornerstone for future smart manufacturing.Read moreRead less