Situational Assessment as a Marker of Cognitive Skill Decay. The aim of this study is to test how differences in exposure to complex tasks change the capacity for situational assessment. Amongst drivers, pilots and electricity controllers, the capacity to assess and respond effectively to changes in the operational environment are critical in sustaining performance and ensuring the safety and security of the public. Establishing the nature of this relationship will enable, for the first time, ob ....Situational Assessment as a Marker of Cognitive Skill Decay. The aim of this study is to test how differences in exposure to complex tasks change the capacity for situational assessment. Amongst drivers, pilots and electricity controllers, the capacity to assess and respond effectively to changes in the operational environment are critical in sustaining performance and ensuring the safety and security of the public. Establishing the nature of this relationship will enable, for the first time, objective measures of cognitive skill decay. In evaluating cognitive skill decay more accurately, we will provide a cost-effective, easily administered tool, enabling practitioners to identify and address areas of development and providing data to anticipate when cognitive skill decay is most likely to occur.Read moreRead less
Road safety and Aboriginal people. This study will involve an in-depth examination of factors underlying the high involvement in road crashes by Aboriginal people in Australia. Using mixed methods in six communities across NSW and South Australia it will inform development of new programs aimed at closing the gap in this important area.
Structural Fuses for Safer and More Economical Bridge Construction. This project aims to develop a novel structural system leading to more economical concrete bridge construction by utilising a customised structural fuse. A significant margin of safety is required in structural design to account for accidental over-loading and to reduce the risk of structural collapse. Such a margin leads to more material usage. Incorporation of a fuse into the structure that is triggered upon over-loading will ....Structural Fuses for Safer and More Economical Bridge Construction. This project aims to develop a novel structural system leading to more economical concrete bridge construction by utilising a customised structural fuse. A significant margin of safety is required in structural design to account for accidental over-loading and to reduce the risk of structural collapse. Such a margin leads to more material usage. Incorporation of a fuse into the structure that is triggered upon over-loading will cause a safer failure mode and prohibit further increase of loading, both of which result in a reduced structure without undermining safety. The project is expected to advance structural theory, and also provide significant benefits to the construction industry via cost reduction and more eco-friendly constructions.Read moreRead less
The Molecular Basis of Nanoparticle Resistance in Mixed-Species Biofilm. The project aims to understand how the globally significant mixed-species growth of pathogens develop resistance to silver nanoparticle, currently one of the most important alternative antimicrobials to antibiotics. The integrated research is to elucidate, for the first time, the nanoparticle multi-targeting toxicity on mixed-species bacterial community and how, in turn, the bacteria activate their cell-to-cell signalling f ....The Molecular Basis of Nanoparticle Resistance in Mixed-Species Biofilm. The project aims to understand how the globally significant mixed-species growth of pathogens develop resistance to silver nanoparticle, currently one of the most important alternative antimicrobials to antibiotics. The integrated research is to elucidate, for the first time, the nanoparticle multi-targeting toxicity on mixed-species bacterial community and how, in turn, the bacteria activate their cell-to-cell signalling for a synergistic defence to adapt to the nanoparticle toxicity. The pioneering knowledge is the foundation for technologies targeting the interspecies metabolite cross-talking to overcome the resistance phenomena, ensuring a long-term efficacy of the alternative antimicrobial on the difficult-to-control pathogenic growth.Read moreRead less
Tranquillising Work Stress: Corporate Climate and Antidepressant Use. This national project will investigate the plausible link between distress at work and Australia’s high levels of antidepressant use, through creative linkage of data from the Australian Workplace Barometer (10-year longitudinal study) to antidepressant medication data (via the national Pharmaceutical Benefits Scheme). The project advances theory by probing the role corporate climate plays in work design, distress, mental hea .... Tranquillising Work Stress: Corporate Climate and Antidepressant Use. This national project will investigate the plausible link between distress at work and Australia’s high levels of antidepressant use, through creative linkage of data from the Australian Workplace Barometer (10-year longitudinal study) to antidepressant medication data (via the national Pharmaceutical Benefits Scheme). The project advances theory by probing the role corporate climate plays in work design, distress, mental health problems and antidepressant use. It will determine if antidepressant use has led to an underestimation of work stress effects. It will estimate the $AUD cost of work related antidepressant use. The project will yield evidence to stimulate corporate climate change to protect worker psychological health and wellbeing.Read moreRead less
Sleepy and sitting: a dual curse for the modern workforce? This project aims to generate new knowledge about the impact of inadequate sleep and prolonged sitting on health markers and performance. Many workers, particularly those working outside standard hours, experience both prolonged sitting and inadequate sleep. Expected outcomes of this project include critical evidence to address the dual burden experienced by a large population of workers who are both sleepy and sitting. This should provi ....Sleepy and sitting: a dual curse for the modern workforce? This project aims to generate new knowledge about the impact of inadequate sleep and prolonged sitting on health markers and performance. Many workers, particularly those working outside standard hours, experience both prolonged sitting and inadequate sleep. Expected outcomes of this project include critical evidence to address the dual burden experienced by a large population of workers who are both sleepy and sitting. This should provide significant benefits for the many working Australians whose health and safety is compromised due to their exposure to inadequate sleep and prolonged sitting. It will also contribute to the evidence-base for workplace policies and public health guidelines.Read moreRead less
Properties of nanomaterials determine their disposal by liver cells. This project aims to understand how the liver handles and is affected by nanomaterials in the body. Nanomaterials are widely used in industrial, environmental, consumer and drug products, but how they affect human health is poorly understood. This project will characterise the spatiotemporal distribution of a set of nanomaterials with defined attributes in naïve and modified livers using chemistry, imaging and biological method ....Properties of nanomaterials determine their disposal by liver cells. This project aims to understand how the liver handles and is affected by nanomaterials in the body. Nanomaterials are widely used in industrial, environmental, consumer and drug products, but how they affect human health is poorly understood. This project will characterise the spatiotemporal distribution of a set of nanomaterials with defined attributes in naïve and modified livers using chemistry, imaging and biological methods. This work is expected to determine how nanomaterials’ attributes direct pathways for liver cell disposal and describe nanomaterial–liver interactions at the cellular level, information crucial in enabling safer nanomaterials for use in products such as drug formulations, sunscreens and cosmetics.Read moreRead less
Climate Change and Burden of Disease: Current Risk and Future Burden. Climate change has had a negative impact on human health. However, few studies have assessed burden of diseases (BOD) for these climate-sensitive/heat attributable diseases. We will generate the first national picture of the climate attributable BOD in Australia, measured in Disability-Adjusted Life Year (DALY), the attribution from climate, and project future BOD under various climatic/demographic change scenarios. This proje ....Climate Change and Burden of Disease: Current Risk and Future Burden. Climate change has had a negative impact on human health. However, few studies have assessed burden of diseases (BOD) for these climate-sensitive/heat attributable diseases. We will generate the first national picture of the climate attributable BOD in Australia, measured in Disability-Adjusted Life Year (DALY), the attribution from climate, and project future BOD under various climatic/demographic change scenarios. This project will rank Australian climate-sensitive/heat attributable diseases by their current burden and projected increase under climate changes, and provide needed scientific evidence to policy-makers in the development, prioritization and implementation of current and future climate change and health adaptation strategies. Read moreRead less