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Validation And Implementation Of A Diabetic Retinopathy Quality Of Life Item Bank
Funder
National Health and Medical Research Council
Funding Amount
$468,362.00
Summary
The current proposal will validate a comprehensive diabetic retinopathy quality of life item bank using a computer adaptive testing system in an Australian, and Singapore-Chinese, -Malay and -Indian sample. The national and international translational applications of the final item bank for researchers, clinicians and policy planners will be substantial, allowing the outcomes of novel treatment therapies for diabetic retinopathy to be accurately assessed from the patient’s perspective resulting ....The current proposal will validate a comprehensive diabetic retinopathy quality of life item bank using a computer adaptive testing system in an Australian, and Singapore-Chinese, -Malay and -Indian sample. The national and international translational applications of the final item bank for researchers, clinicians and policy planners will be substantial, allowing the outcomes of novel treatment therapies for diabetic retinopathy to be accurately assessed from the patient’s perspective resulting in better allocation of funding and resources.Read moreRead less
Improving Neurodevelopmental Outcomes Of Preterm Infants
Funder
National Health and Medical Research Council
Funding Amount
$312,085.00
Summary
In Australia over 20,000 babies are born preterm each year. Preterm babies are at risk of long term developmental problems including movement, learning and behavioural impairments. This research will examine both neurodevelopment and brain development of very preterm (born <30 weeksÍ gestation) and late preterm (32-36 weeksÍ gestation) babies from birth to into early childhood so that we can understand how gestational age at birth relates to development, brain growth and interventions.
Cellular Mechanisms Of Functional Deficits In Experimental Glaucoma
Funder
National Health and Medical Research Council
Funding Amount
$294,541.00
Summary
If successful, our approach will potentially have a major impact on the treatment of diabetic retinopathy and possibly on all diabetic vascular diseases. A single injection might only be necessary to prevent the development of diabetic retinopathy, which would represent a significant weapon in the management of patients. In addition, successful application of secretion gene therapy in the eye might open up the possibility to introduce the same concept for the treatment of larger organs undergoin ....If successful, our approach will potentially have a major impact on the treatment of diabetic retinopathy and possibly on all diabetic vascular diseases. A single injection might only be necessary to prevent the development of diabetic retinopathy, which would represent a significant weapon in the management of patients. In addition, successful application of secretion gene therapy in the eye might open up the possibility to introduce the same concept for the treatment of larger organs undergoing microvascular changes as a result of diabetes.Read moreRead less
Improving Visual Outcomes In Patients With Diabetic Macular Oedema Undergoing Cataract Surgery: A Prospective Randomised Clinical Trial (the DiMECat Trial)
Funder
National Health and Medical Research Council
Funding Amount
$187,322.00
Summary
Cataract and diabetic retinopathy are the leading causes of visual loss in patients with diabetes, but unfortunately, cataract surgery in these patients often results in a loss of vision, rather than an improvement. The purpose of this study is to improve the visual outcomes in this group of patients, through the use of new, injected medicines that are given at the time of cataract surgery, thereby potentially changing current medical practice.
Aberrant Brain Development In High Risk Newborns: Relationship With Long Term Developmental Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$185,932.00
Summary
Brain development and long term outcomes are altered in high-risk babies. This research looks at the developmental outcomes of 3 high-risk baby groups i.e. late preterm babies (born 4-8 weeks premature), babies with seizures, and preterm babies who have received probiotics in the newborn nursery. In addition, how their brain development may be different compared with healthy term babies will be studies using advanced magnetic resonance imaging.
Using New Retinal Imaging Technologies To Improve Treatment And Classification Of Diabetic Retinopathy
Funder
National Health and Medical Research Council
Funding Amount
$227,644.00
Summary
Diabetic retinopathy is the leading cause of blindness in Australia. This project aims to use new ways of imaging changes in the back of the eye to try to improve the treatment and diagnosis of diabetic retinopathy.