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Industrial Transformation Research Hubs - Grant ID: IH190100022
Funder
Australian Research Council
Funding Amount
$4,787,259.00
Summary
ARC Research Hub for Sustainable Crop Protection. The Hub aims to develop and commercialise an innovative biological alternative to chemical fungicides targeting economically significant diseases of broadacre and horticultural crops. It addresses industry challenges of fungicide resistance, chemical residues in food, off-target effects and environmental harm. It builds on ground-breaking ‘BioClay’ platform to deliver pathogen targeting RNA using clay particles as non-genetically modified crop pr ....ARC Research Hub for Sustainable Crop Protection. The Hub aims to develop and commercialise an innovative biological alternative to chemical fungicides targeting economically significant diseases of broadacre and horticultural crops. It addresses industry challenges of fungicide resistance, chemical residues in food, off-target effects and environmental harm. It builds on ground-breaking ‘BioClay’ platform to deliver pathogen targeting RNA using clay particles as non-genetically modified crop protection. An expert multidisciplinary team uniting science, commercial and social licence pathways ensures industry and consumer uptake advancing $60B Australian Agriculture. The Hub translates to increased productivity, market access and enhanced environmental credentials of Australian food.
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Detection and viability of waterborne pathogens using a gut-on-chip. This project aims to resolve a significant problem for water utilities. Microbial pathogens Cryptosporidium, norovirus and adenovirus are the main public health concern for drinking water in developed nations. Water monitoring is limited by the lack of fast, reliable detection methods and viability assays for these pathogens. This project will use a novel gut-on-a-chip to develop for the first time rapid infectivity assays for ....Detection and viability of waterborne pathogens using a gut-on-chip. This project aims to resolve a significant problem for water utilities. Microbial pathogens Cryptosporidium, norovirus and adenovirus are the main public health concern for drinking water in developed nations. Water monitoring is limited by the lack of fast, reliable detection methods and viability assays for these pathogens. This project will use a novel gut-on-a-chip to develop for the first time rapid infectivity assays for Cryptosporidium, norovirus and adenovirus. Significant benefits include improved diagnostics and water disinfection assays, improved water treatment and reduced costs with global impact.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC230100027
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Training Centre in Plant Biosecurity. The ARC Training Centre in Plant Biosecurity aims to deliver a solution for Australia’s increasing biosecurity risk through generational change in its workforce coupled with breakthrough technologies. It will launch an innovative training program for future leaders who will build relationships with end users and engage meaningfully with communities for effective implementation strategies. Expected outcomes include a cohort of highly skilled graduates tha ....ARC Training Centre in Plant Biosecurity. The ARC Training Centre in Plant Biosecurity aims to deliver a solution for Australia’s increasing biosecurity risk through generational change in its workforce coupled with breakthrough technologies. It will launch an innovative training program for future leaders who will build relationships with end users and engage meaningfully with communities for effective implementation strategies. Expected outcomes include a cohort of highly skilled graduates that will innovate novel diagnostic technologies, enable data-driven decision platforms and address barriers to biosecurity adoption. This suite of graduates and technologies will transform the plant biosecurity sector to protect Australia’s $5.7 trillion natural and productive ecosystems.Read moreRead less
ARC Centre of Excellence for Gravitational Wave Discovery. ARC Centre of Excellence for Gravitational Wave Discovery. The mission of our Centre is to use gravitational waves to investigate the fundamental nature of relativistic gravity, ultra-dense matter, and cosmology. This will generate critical discoveries that cement Australia's leadership role in the gravitational wave mega-science instruments of the 2030s and 2040s. By bringing together a world-class team with broad and complementary expe ....ARC Centre of Excellence for Gravitational Wave Discovery. ARC Centre of Excellence for Gravitational Wave Discovery. The mission of our Centre is to use gravitational waves to investigate the fundamental nature of relativistic gravity, ultra-dense matter, and cosmology. This will generate critical discoveries that cement Australia's leadership role in the gravitational wave mega-science instruments of the 2030s and 2040s. By bringing together a world-class team with broad and complementary expertise we will develop core technologies for future detectors, discover new sources of gravitational waves, probe fundamental physics, and lay the foundations for an Australian gravitational wave observatory. Our discoveries will inspire Australia's youth to pursue high tech careers and position our staff and students to become leaders in both industry and academia.Read moreRead less
Novel source of excited metastable atoms for Atom Trap Trace Analysis. This project aims to understand and to control light-induced processes in atoms by using finely shaped and tailored laser pulses, focusing on efficient production of excited metastable atoms. This is critical for efficient Atom Trap Trace Analysis, the most advanced technique for dating ground water and geological samples. Expected outcomes of this project include new and enhanced knowledge of physics of light-matter interact ....Novel source of excited metastable atoms for Atom Trap Trace Analysis. This project aims to understand and to control light-induced processes in atoms by using finely shaped and tailored laser pulses, focusing on efficient production of excited metastable atoms. This is critical for efficient Atom Trap Trace Analysis, the most advanced technique for dating ground water and geological samples. Expected outcomes of this project include new and enhanced knowledge of physics of light-matter interactions, developing an efficient, clean source of excited metastable atoms, and integrating that source into the Australian National Facility for dating geological samples. This should provide significant benefits, such as significant improvement of operational efficiency and productivity of that facility.Read moreRead less
Advancing the visualisation and quantification of nephrons with MRI. . This project aims to characterise key components of nephrons, the glomeruli and tubules, using magnetic resonance imaging without contrast agents, in combination with Deep Learning and super-resolution techniques. Nephrons, the basic functional unit of the kidney, are critical to the maintenance of the body’s homeostasis. Their number and architecture are critical determinants of kidney function. The expected outcomes are inn ....Advancing the visualisation and quantification of nephrons with MRI. . This project aims to characterise key components of nephrons, the glomeruli and tubules, using magnetic resonance imaging without contrast agents, in combination with Deep Learning and super-resolution techniques. Nephrons, the basic functional unit of the kidney, are critical to the maintenance of the body’s homeostasis. Their number and architecture are critical determinants of kidney function. The expected outcomes are innovative semi-automated nephron visualisation and quantitation tools that enable efficient renal phenotyping. Techniques tailored to widely accessible preclinical research scanners are expected to accelerate research into genetic and environmental factors affecting kidney microstructure in embryonic and post-natal life.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC220100050
Funder
Australian Research Council
Funding Amount
$4,508,426.00
Summary
ARC Training Centre for Environmental and Agricultural Solutions to Antimicrobial Resistance (ARC CEA-StAR). The ARC Training Centre for Environmental and Agricultural Solutions to Antimicrobial Resistance aims to develop industry-led solutions and train a new generation of researchers to combat the impact of antimicrobial resistance (AMR) on agribusiness and the environment.
AMR is a global health and economic threat that epitomises the need for a ‘One Health’ collaborative approach encompassi ....ARC Training Centre for Environmental and Agricultural Solutions to Antimicrobial Resistance (ARC CEA-StAR). The ARC Training Centre for Environmental and Agricultural Solutions to Antimicrobial Resistance aims to develop industry-led solutions and train a new generation of researchers to combat the impact of antimicrobial resistance (AMR) on agribusiness and the environment.
AMR is a global health and economic threat that epitomises the need for a ‘One Health’ collaborative approach encompassing the interconnection between people, animals, plants, and their shared environment.
Expected outcomes of this collaborative program include a cohort of researchers trained in industry-relevant techniques, furnishing solutions to partner-defined AMR challenges, and providing significant benefits by positioning Australia as a global leader in reducing AMR.Read moreRead less
Finding the targets of natural products in complex botanical extracts. Many plants are used for nutritional and traditional medicine purposes and have demonstrated, evidence based effects. However, standard methods to identify single chemical compounds responsible for the observed effects fail as they rely on a single compound having a single target and ignore the overall effects of many interacting compounds on many targets. In this application we propose a new method to simultaneously identify ....Finding the targets of natural products in complex botanical extracts. Many plants are used for nutritional and traditional medicine purposes and have demonstrated, evidence based effects. However, standard methods to identify single chemical compounds responsible for the observed effects fail as they rely on a single compound having a single target and ignore the overall effects of many interacting compounds on many targets. In this application we propose a new method to simultaneously identify the molecular targets of many compounds in complex plant extracts, along with their subsequent validation by responses in gene expression to the plant extract. This research will revolutionise understanding of the nutritional and medicinal effects of plants and will allow our partners to accelerate commercialisation. Read moreRead less
The psychology of gridlock: Compromise, coalitions, and radicalisation. This project aims to test an innovative psychological model of collective gridlock. Using interviews, surveys, experiments, small group research, and analysis of social media data, the project aims to examine critical pathways in gridlock psychology, where opponents are locked into mutually suboptimal outcomes, unable to move forward. These pathways include the exit or self-censorship of moderates; normative pressure towards ....The psychology of gridlock: Compromise, coalitions, and radicalisation. This project aims to test an innovative psychological model of collective gridlock. Using interviews, surveys, experiments, small group research, and analysis of social media data, the project aims to examine critical pathways in gridlock psychology, where opponents are locked into mutually suboptimal outcomes, unable to move forward. These pathways include the exit or self-censorship of moderates; normative pressure towards purity and refusal to compromise; tactical choices to avoid coalitions; and radicalisation. The research aims to develop novel interventions to reduce polarisation and radicalisation, and to promote compromises, which together will help society respond more nimbly and effectively to social and environmental challenges.Read moreRead less
Dynamics of forgiveness and self-forgiveness. This project aims to study the dynamics between forgiveness and self-forgiveness following hurt and wrongdoing in interpersonal relationships. Prior research has focused on individuals’ traits, cognition and affect as determinants of forgiveness and self-forgiveness. This project will study dyadic-level dynamics between both parties, interdependencies between forgiveness and self-forgiveness in a dialogical process of moral repair. Expected outcomes ....Dynamics of forgiveness and self-forgiveness. This project aims to study the dynamics between forgiveness and self-forgiveness following hurt and wrongdoing in interpersonal relationships. Prior research has focused on individuals’ traits, cognition and affect as determinants of forgiveness and self-forgiveness. This project will study dyadic-level dynamics between both parties, interdependencies between forgiveness and self-forgiveness in a dialogical process of moral repair. Expected outcomes include an advanced understanding of the psychology of moral repair and the restoration of relationships between individuals, couples, managers and clinicians following wrongdoing and interpersonal transgressions. The project will benefit family wellbeing and employee productivity by improving reconciliation and alleviating pain, stress and costs, both in families and at the workplace.Read moreRead less