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ARC/NHMRC Research Network for Parasitology. The ARC Network for Parasitology will focus and coordinate Australia's world class fundamental, strategic and applied parasitology research. This targeted approach will raise Australia's standing in the field, assist in the community's understanding of parasitology and biosecurity and maintain and improve Australia's capacity for keeping its stock, crops, wildlife and people disease-free. On an international scale, the Network will work with other cou ....ARC/NHMRC Research Network for Parasitology. The ARC Network for Parasitology will focus and coordinate Australia's world class fundamental, strategic and applied parasitology research. This targeted approach will raise Australia's standing in the field, assist in the community's understanding of parasitology and biosecurity and maintain and improve Australia's capacity for keeping its stock, crops, wildlife and people disease-free. On an international scale, the Network will work with other countries to develop new technologies for the detection and eradication of parasites. This emphasis will not only protect Australia's borders but will assist our near neighbours and lead to the development of technologies with an economic benefit to Australia.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100087
Funder
Australian Research Council
Funding Amount
$450,000.00
Summary
Regional Facility for Molecular Characterisation and Mapping. Researchers at the Schools of Chemistry at The Australian National University and University of Wollongong are involved in a range of projects where new molecules are synthesised or discovered in natural products such as rainforest plants and marine organisms. Some of the molecules have already shown promise against diseases such as Alzheimer's and cardiovascular disease. In order to fully characterise these molecules, two complementa ....Regional Facility for Molecular Characterisation and Mapping. Researchers at the Schools of Chemistry at The Australian National University and University of Wollongong are involved in a range of projects where new molecules are synthesised or discovered in natural products such as rainforest plants and marine organisms. Some of the molecules have already shown promise against diseases such as Alzheimer's and cardiovascular disease. In order to fully characterise these molecules, two complementary mass spectrometers, replacing ageing instrumentation will be commissioned at each site. In addition, researchers in Wollongong will acquire a MALDI mass spectrometer capable of imaging the distribution of molecules on tissues that may be pathologically important.Read moreRead less
ARC Centre of Excellence in Convergent Bio-Nano Science and Technology. The CoE in Convergent Bio-Nano Science &Technology comprises a multi-disciplinary team focused on research aiming to understand and control the interface of materials with biological systems. The Centre will exploit knowledge of the bio-nano interface to design materials that transport and deliver vaccines, drugs and gene therapy agents, and to design new diagnostic agents and devices. Nanomedicines are on the cusp of revol ....ARC Centre of Excellence in Convergent Bio-Nano Science and Technology. The CoE in Convergent Bio-Nano Science &Technology comprises a multi-disciplinary team focused on research aiming to understand and control the interface of materials with biological systems. The Centre will exploit knowledge of the bio-nano interface to design materials that transport and deliver vaccines, drugs and gene therapy agents, and to design new diagnostic agents and devices. Nanomedicines are on the cusp of revolutionizing diagnosis and therapy in many diseases. The CoE will be the focus of bio-nano research activity in Australia, uniting universities, research agencies, institutes and companies. The expected outcomes are better diagnostic and therapeutic tools designed via an enhanced understanding of the bio-nano-interface.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989374
Funder
Australian Research Council
Funding Amount
$550,000.00
Summary
South Australian High-Resolution and Ion-Mobility Mass Spectrometry Facility. The analytical facility will enhance (i) fundamental research to understand the mechanisms of the reactions of charged species with neutral molecules, and (ii) the provision of structural information, including the precise atomic composition of any molecule, small or large. Research supported by this facility includes (a)nanotechnology, including supramolecular chemistry, (b) bioscience: cancer research, neurodegenera ....South Australian High-Resolution and Ion-Mobility Mass Spectrometry Facility. The analytical facility will enhance (i) fundamental research to understand the mechanisms of the reactions of charged species with neutral molecules, and (ii) the provision of structural information, including the precise atomic composition of any molecule, small or large. Research supported by this facility includes (a)nanotechnology, including supramolecular chemistry, (b) bioscience: cancer research, neurodegenerate diseases (e.g. Parkinson's disease) osteoarthritis, inflammation, cardiac diseases and synthetic approaches to anticancer and other drugs.Read moreRead less
Many Ys in monotremes: multiple sex chromosomes and sex determination in platypus and echidna. Platypus and Echidna are Australian icons, even featuring on our coins. Their unusual biology and ancient relationship to humans make them unique for understanding the mammalian genome, as demonstrated by our recent discovery of ten sex chromosomes in platypus that link mammal and bird sex. Still little is known about their genome, embryo development and how sex is determined. We will identify new gene ....Many Ys in monotremes: multiple sex chromosomes and sex determination in platypus and echidna. Platypus and Echidna are Australian icons, even featuring on our coins. Their unusual biology and ancient relationship to humans make them unique for understanding the mammalian genome, as demonstrated by our recent discovery of ten sex chromosomes in platypus that link mammal and bird sex. Still little is known about their genome, embryo development and how sex is determined. We will identify new genes on all ten sex chromosomes and investigate how they determine sex. The set up of an Australian Monotreme Resource Centre will be crucial for this research and attract worldwide high profile collaborations. We will answer important general questions in monotreme biology and contribute to our understanding of sexual abnormalities in humans.Read moreRead less
Psyllids as biosecurity threats to plantation and native eucalypts in Australia and internationally. Psyllids are tiny cicada-like insects that are economic pests of forestry and horticulture because the saliva injected when feeding causes leaf death and some vector plant diseases. Advanced technologies and procedures will be used to determine what makes plants susceptible to psyllids and to improve Australian preparedness ahead of an incursion.
Industrial Transformation Research Hubs - Grant ID: IH190100022
Funder
Australian Research Council
Funding Amount
$4,787,259.00
Summary
ARC Research Hub for Sustainable Crop Protection. The Hub aims to develop and commercialise an innovative biological alternative to chemical fungicides targeting economically significant diseases of broadacre and horticultural crops. It addresses industry challenges of fungicide resistance, chemical residues in food, off-target effects and environmental harm. It builds on ground-breaking ‘BioClay’ platform to deliver pathogen targeting RNA using clay particles as non-genetically modified crop pr ....ARC Research Hub for Sustainable Crop Protection. The Hub aims to develop and commercialise an innovative biological alternative to chemical fungicides targeting economically significant diseases of broadacre and horticultural crops. It addresses industry challenges of fungicide resistance, chemical residues in food, off-target effects and environmental harm. It builds on ground-breaking ‘BioClay’ platform to deliver pathogen targeting RNA using clay particles as non-genetically modified crop protection. An expert multidisciplinary team uniting science, commercial and social licence pathways ensures industry and consumer uptake advancing $60B Australian Agriculture. The Hub translates to increased productivity, market access and enhanced environmental credentials of Australian food.
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Making Green Guard® greener: enhancing the efficacy of a biopesticide. The project aims to identify naturally occurring micro-organisms to increase the effectiveness of Green Guard ®, which is a biopesticide used against the Australian plague locust. The project will use next-generation sequencing and other molecular techniques to potentially identify candidate microbes or combinations of microbes that can be added to Green Guard to enhance locust susceptibility. The project also aims to quantif ....Making Green Guard® greener: enhancing the efficacy of a biopesticide. The project aims to identify naturally occurring micro-organisms to increase the effectiveness of Green Guard ®, which is a biopesticide used against the Australian plague locust. The project will use next-generation sequencing and other molecular techniques to potentially identify candidate microbes or combinations of microbes that can be added to Green Guard to enhance locust susceptibility. The project also aims to quantify the interactive impact of temperature and nutrition on immune function, disease resistance and host-plant quality of plague locusts; and to explore the combined effects of temperature, habitat and Green Guard, in combination with candidate microbes or pathogens, on the behaviour and collective movement of locusts. It is anticipated that this will have implications for management and control strategies.Read moreRead less
What drives parasite spread through social networks: lessons from lizards. Australia's biodiversity is continually threatened by new epidemics of local and foreign diseases and parasites. This project will enhance our understanding of how these diseases spread, allowing more effective controls to be developed to protect wildlife species, animal populations and, ultimately, Australian ecosystems.
Parasite transmission through social networks in the pygmy bluetongue lizard. Australia's biodiversity is continually threatened by new epidemics of diseases and parasites, some local, others from overseas. This project will provide information on how they spread so that more effective management of these diseases can be developed to protect wildlife species, animal populations and, ultimately, Australian ecosystems.