Improving respiratory drug delivery through targeted nozzle design. The project aims to develop designs for inhaler components which significantly reduce the existing variability in the sprays they produce, as well as an enhanced capacity to predict inhaler performance through development of new empirical models. This project will combine recently developed synchrotron x-ray measurement techniques with traditional visible light diagnostics to develop a greater understanding of the link between t ....Improving respiratory drug delivery through targeted nozzle design. The project aims to develop designs for inhaler components which significantly reduce the existing variability in the sprays they produce, as well as an enhanced capacity to predict inhaler performance through development of new empirical models. This project will combine recently developed synchrotron x-ray measurement techniques with traditional visible light diagnostics to develop a greater understanding of the link between the geometry of pressurised, metered-dose inhaler components and the drug particles these devices produce. The long term benefit from this research will be improved delivery efficiency and shorter product development times, leading to reduced dose-rate costs. This understanding will enable the development of the next generation of treatment devices with enhanced efficiency in delivery of the drugs used to treat these diseases and reduced costs per dose.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100018
Funder
Australian Research Council
Funding Amount
$362,441.00
Summary
Engineering suspended particle sprays through controlled cavitation. This project aims to use cavitation to engineer particle size in sprays of micronised particles suspended in a propellant, and develop a physical mechanism for this process. Understanding how cavitation affects the size of agglomerates in the liquid phase and droplet size in a spray is critical to developing spray devices that require precise control over the final particle size. This will be achieved through high-resolution op ....Engineering suspended particle sprays through controlled cavitation. This project aims to use cavitation to engineer particle size in sprays of micronised particles suspended in a propellant, and develop a physical mechanism for this process. Understanding how cavitation affects the size of agglomerates in the liquid phase and droplet size in a spray is critical to developing spray devices that require precise control over the final particle size. This will be achieved through high-resolution optical imaging techniques and synchrotron X-ray diagnostics. This project is expected to provide physical insight with applications for inhaled and topical pharmaceutical sprays, and industry spray drying of food products.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100222
Funder
Australian Research Council
Funding Amount
$440,000.00
Summary
Time-resolved tomographic particle image velocimetry facility. The experimental information gained from measurements provided by this infrastructure will lead to significant advances in understanding turbulent flows and the dynamics of solid structures, which will impact a broad range of engineering and geophysical fields. Some specific examples include the development of efficient turbulence control strategies for the reduction of skin-friction drag and improved combustion processes, resulting ....Time-resolved tomographic particle image velocimetry facility. The experimental information gained from measurements provided by this infrastructure will lead to significant advances in understanding turbulent flows and the dynamics of solid structures, which will impact a broad range of engineering and geophysical fields. Some specific examples include the development of efficient turbulence control strategies for the reduction of skin-friction drag and improved combustion processes, resulting in not only better fuel efficiency for vehicles but also reduced CO2 and pollutant emissions. Significant advances can also be made in understanding the dispersion of pollutants in the atmosphere, wind turbine design and the development of lighter and stronger intelligent materials with improved fatigue life.Read moreRead less
Unravelling the scale interactions of wall turbulence: experiment, physical modelling, next-generation numerical simulation. Turbulent fluid flows near solid surfaces are present in many areas of everyday life: from the drag experienced on air, sea and road vehicles, to governing the mixing processes in combustion chambers, and in the transport of pollutants and particulates in our cities and towns. Unfortunately our understanding of these complex flows is limited, and hence so to is our ability ....Unravelling the scale interactions of wall turbulence: experiment, physical modelling, next-generation numerical simulation. Turbulent fluid flows near solid surfaces are present in many areas of everyday life: from the drag experienced on air, sea and road vehicles, to governing the mixing processes in combustion chambers, and in the transport of pollutants and particulates in our cities and towns. Unfortunately our understanding of these complex flows is limited, and hence so to is our ability to model or control them. This project addresses this problem with the goal of providing new physical insights and models that can be used for efficient and accurate numerical simulations. The simulations will not only compute the average statistics but also the time-varying properties, which are crucial in many engineering and environmental processes.Read moreRead less
Silencing the screech tone - noise suppression in supersonic jets. The focus of this research is to further develop understanding of the fundamental mechanics of the aeroacoustic phenomenon known as screech. From this deeper understanding a range of tailored control mechanisms are expected to be developed to reduce or eliminate the effects of screech in the engines of high-speed aircraft. The research builds on existing expertise and established experimental facilities. As well as an improved un ....Silencing the screech tone - noise suppression in supersonic jets. The focus of this research is to further develop understanding of the fundamental mechanics of the aeroacoustic phenomenon known as screech. From this deeper understanding a range of tailored control mechanisms are expected to be developed to reduce or eliminate the effects of screech in the engines of high-speed aircraft. The research builds on existing expertise and established experimental facilities. As well as an improved understanding of fundamental mechanism, the expected outcomes of the research are more efficient active and passive flow control devices for the reduction of supersonic jet noise.Read moreRead less
Stability, transition and heat transfer in thermally coupled natural convection boundary layers. Thermally coupled natural convection systems occur when a conducting vertical wall separates two fluids at different temperatures. Such configurations occur, for example, at a window separating the interior of a room from the outside or when a container of fluid is placed in a refrigerator. Improved building heating/cooling and ventilation, and more efficient refrigeration systems, require a thoroug ....Stability, transition and heat transfer in thermally coupled natural convection boundary layers. Thermally coupled natural convection systems occur when a conducting vertical wall separates two fluids at different temperatures. Such configurations occur, for example, at a window separating the interior of a room from the outside or when a container of fluid is placed in a refrigerator. Improved building heating/cooling and ventilation, and more efficient refrigeration systems, require a thorough understanding and predictive capability for these flows. This project will develop experimental, numerical and analytic tools to predict these flows and provide simple scaling relations for bulk flow parameters such as the heat transfer across the wall, which will be of immediate use in the associated industries.Read moreRead less
A novel approach to controlling boundary-layer separation. This project will involve fundamental research into the control of the fluid dynamical phenomena of boundary-layer separation and transition to turbulence. The project will be built upon a firm foundation of mathematical modelling of the complex behaviour of fluid flows that are near the onset of flow separation or turbulence. The project will produce results that will permit the development of control strategies that can be implemented ....A novel approach to controlling boundary-layer separation. This project will involve fundamental research into the control of the fluid dynamical phenomena of boundary-layer separation and transition to turbulence. The project will be built upon a firm foundation of mathematical modelling of the complex behaviour of fluid flows that are near the onset of flow separation or turbulence. The project will produce results that will permit the development of control strategies that can be implemented in a wide variety of important technological applications, such as drag reduction in the aerospace and ship industries as well as the control of stall (or loss of lift) in modern aircraft.Read moreRead less
Practical wall-turbulence drag reduction through adaptive control. Long term increases in the price of aviation fuel disproportionately impacts on Australian carriers, given our geographic isolation and the resulting greater percentage of long-haul flights. The resulting higher fares will also have a direct impact on international tourism to Australia. One way to reduce the impact of rising fuel cost, and to reduce CO2 and other emissions at the same time, is to decrease drag on aircraft. This ....Practical wall-turbulence drag reduction through adaptive control. Long term increases in the price of aviation fuel disproportionately impacts on Australian carriers, given our geographic isolation and the resulting greater percentage of long-haul flights. The resulting higher fares will also have a direct impact on international tourism to Australia. One way to reduce the impact of rising fuel cost, and to reduce CO2 and other emissions at the same time, is to decrease drag on aircraft. This project will develop understanding in wall turbulence and adaptive control, and use this to experimentally demonstrate active reductions in skin friction drag. The results are equally applicable to a range of other applications including sea transport, pipe flows and combustor designs.Read moreRead less
Enhancement of Heat Transfer by Stimulated Transition to Turbulence in Natural Convection Boundary Layers on Heated Walls. The aim of this project is to increase the heat transfer from heated vertical surfaces to an ambient fluid by stimulating an early transition to turbulence. Such passive heat transfer occurs in heat transfer devices, natural ventilation systems and in many environmental settings. Enhanced heat transfer will greatly improve the performance of these systems. The project will ....Enhancement of Heat Transfer by Stimulated Transition to Turbulence in Natural Convection Boundary Layers on Heated Walls. The aim of this project is to increase the heat transfer from heated vertical surfaces to an ambient fluid by stimulating an early transition to turbulence. Such passive heat transfer occurs in heat transfer devices, natural ventilation systems and in many environmental settings. Enhanced heat transfer will greatly improve the performance of these systems. The project will provide the length scales, frequency and amplification rate for the occurence of the secondary spanwise mode that is the primary mechanism for turbulent transition. This will provide guidance for the development of appropriate roughness elements and heating length and time scales.Read moreRead less
Systematically model the large-scale complexity of turbulent floods and thin film flows. This project continues development of new models, and computer
simulation, of turbulent flood, river and estuarine flow. The models
will be based systematically upon established turbulence models to
resolve accurately the complex physical processes. The development of
new and robust computer models for thin layers of coating fluid will
aid many industrial processes. We also aim to provide correct ini ....Systematically model the large-scale complexity of turbulent floods and thin film flows. This project continues development of new models, and computer
simulation, of turbulent flood, river and estuarine flow. The models
will be based systematically upon established turbulence models to
resolve accurately the complex physical processes. The development of
new and robust computer models for thin layers of coating fluid will
aid many industrial processes. We also aim to provide correct initial
conditions and boundary conditions for simpler cases of the above
flows. The approach leads to a greater understanding of the range of
applicability of the models through better estimating the errors in the
modelling process. The project develops a fundamental enabling
methodology for engineering and the sciences.
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