Engineering an environmentally-friendly metered dose inhaler. This project aims to deliver a novel simulation framework to accurately predict the behaviour of metered dose inhaler sprays using advanced numerical methods for flash-evaporating turbulent flows developed by the investigators. The project expects to generate new knowledge of the complex physics which occur in these devices through a first of its kind combination of unsteady non-equilibrium thermodynamics, turbulence and spray models. ....Engineering an environmentally-friendly metered dose inhaler. This project aims to deliver a novel simulation framework to accurately predict the behaviour of metered dose inhaler sprays using advanced numerical methods for flash-evaporating turbulent flows developed by the investigators. The project expects to generate new knowledge of the complex physics which occur in these devices through a first of its kind combination of unsteady non-equilibrium thermodynamics, turbulence and spray models. Expected outcomes of this project include a novel ability to predict and optimise the performance of inhalers to suit environmentally-friendly replacement propellants. This will significantly benefit the pharmaceutical sector as it will accelerate the design of next-generation inhalers and propellants.Read moreRead less
Bridging the gap between global mechanics and regional imaging in the lungs. The detailed mechanics of breathing are not well understood, due to a lack of regional lung measurement techniques. This project aims to develop a powerful analysis tool to image in vivo mechanical properties of the lungs. The expected outcome of this project is a novel platform for investigation and understanding of lung function, enabling information previously only available for the whole lung to be calculated for lo ....Bridging the gap between global mechanics and regional imaging in the lungs. The detailed mechanics of breathing are not well understood, due to a lack of regional lung measurement techniques. This project aims to develop a powerful analysis tool to image in vivo mechanical properties of the lungs. The expected outcome of this project is a novel platform for investigation and understanding of lung function, enabling information previously only available for the whole lung to be calculated for local lung regions within the body. The image analysis methods developed are intended to enable respiratory researchers to investigate lung function in unprecedented detail, leading to new insights into the workings of this complicated and vital organ. Read moreRead less
Enabling precise droplet control in hydrofluorocarbon free sprays. This project aims to investigate the use of blended propellants to replace hydrofluorocarbons in technical aerosols. This project expects to generate new knowledge in the area of multiphase fluid mechanics and aerosol science through a combination of modeling, optical and synchrotron X-ray measurement techniques. Expected outcomes of this project include a capacity to develop environmentally friendly technical aerosol formulation ....Enabling precise droplet control in hydrofluorocarbon free sprays. This project aims to investigate the use of blended propellants to replace hydrofluorocarbons in technical aerosols. This project expects to generate new knowledge in the area of multiphase fluid mechanics and aerosol science through a combination of modeling, optical and synchrotron X-ray measurement techniques. Expected outcomes of this project include a capacity to develop environmentally friendly technical aerosol formulations which can match and potentially outperform currently available hydrofluorocarbon based products. This should provide significant benefits to the pharmaceutical industry through the generation of new knowledge regarding the fundamental physics of multicomponent sprays.Read moreRead less
Wake dynamics of oscillating cylinder in steady currents. This project aims at advancing knowledge in flow/structure interactions and developing improved methodology for predicting wave and current loading on marine structures, which are vital in many practical applications such as extraction of oil and gas resources and renewable energy from the ocean. The improved methodology and much-needed database of hydrodynamic force coefficients developed through this project for estimating hydrodynamic ....Wake dynamics of oscillating cylinder in steady currents. This project aims at advancing knowledge in flow/structure interactions and developing improved methodology for predicting wave and current loading on marine structures, which are vital in many practical applications such as extraction of oil and gas resources and renewable energy from the ocean. The improved methodology and much-needed database of hydrodynamic force coefficients developed through this project for estimating hydrodynamic loading on marine structures will significantly reduce the high, costly uncertainly levels that are being experienced in the design, construction and maintenance of marine structures (and facilities) and increase the competiveness of Australian relevant industries. Read moreRead less
Emerging Techniques For Earlier Diagnosis And Assessment Of Severity And Progression Of Artificial Stone Silicosis
Funder
National Health and Medical Research Council
Funding Amount
$994,642.00
Summary
Stonemasons who have worked with engineered stone have been shown to develop a rapidly progressive and potentially fatal form of silicosis. This research will use data from affected workers from Victoria, Western Australia and Queensland. The research will comprise a suite of projects to investigate many uncertainties related to radiological screening methods, as well as investigating new methods to assess disease severity and identify indicators of progression to inform future practice.
Mathematical and computational models for agrichemical retention on plants. Mathematical and computational models for agrichemical retention on plants. This project aims to build interactive software that simulates agrichemical spraying for multiple virtual plants reconstructed from scanned data. Mathematical modelling and computer simulation could offer an alternative to expensive experimental programs for agrichemical spraying of plants. This project will use contemporary fluid mechanics to bu ....Mathematical and computational models for agrichemical retention on plants. Mathematical and computational models for agrichemical retention on plants. This project aims to build interactive software that simulates agrichemical spraying for multiple virtual plants reconstructed from scanned data. Mathematical modelling and computer simulation could offer an alternative to expensive experimental programs for agrichemical spraying of plants. This project will use contemporary fluid mechanics to build practical mathematical models for droplet impaction, spreading and evaporation on leaf surfaces, and experimentally calibrate and validate the models. The software is expected to drive the development of agrichemical products that increase retention, minimise environmental impacts, and reduce costs for end-users.Read moreRead less
How do vortices live in spatio-temporally complex flows? The project aims to understand the fundamental mechanism of vortices occurring in flows involving spatio-temporal complexity, by using the combination of dynamical systems theory and asymptotic analysis. This innovative combined mathematical analysis will be coupled with sophisticated computations to be enabled by the international interdisciplinary collaboration between the Mathematics and Engineering at Australia and Japan. The expected ....How do vortices live in spatio-temporally complex flows? The project aims to understand the fundamental mechanism of vortices occurring in flows involving spatio-temporal complexity, by using the combination of dynamical systems theory and asymptotic analysis. This innovative combined mathematical analysis will be coupled with sophisticated computations to be enabled by the international interdisciplinary collaboration between the Mathematics and Engineering at Australia and Japan. The expected outcomes are breakthroughs in the fundamental understanding of turbulence. This should lead to significant insight into better turbulent modellings used in, for example, wide range of engineering, physiological and geophysical flows.Read moreRead less
When quantum is not desirable: quantum noise vs. quantum technologies. One of the key remaining obstacles to the successful deployment of quantum computers & sensors in science, industry, and society is the existence of noise sources that are themselves quantum, and thus have an unmatched potential for disruption. This project will attack this problem by providing (i) a detailed understanding of the impact of quantum noise sources, and developing protocols to (ii) characterize and (iii) overcome ....When quantum is not desirable: quantum noise vs. quantum technologies. One of the key remaining obstacles to the successful deployment of quantum computers & sensors in science, industry, and society is the existence of noise sources that are themselves quantum, and thus have an unmatched potential for disruption. This project will attack this problem by providing (i) a detailed understanding of the impact of quantum noise sources, and developing protocols to (ii) characterize and (iii) overcome the negative effects such realistic noise entails. In taking this necessary step for the implementation of these breakthrough technologies, it will not only significantly advance knowledge but will have a direct impact in the development of a technology in which Australia and other leading nations are heavily invested.Read moreRead less
From superintegrability to quasi-exact solvability: theory and application. This project aims to develop mathematical techniques to resolve longstanding problems in the area of integrability and exact solvability. Quantum integrable systems and exact solvable models are of central importance for understanding the correct behaviours of complex quantum problems without approximation. This project aims to construct sophisticated mathematical tools to settle key questions across a variety of models ....From superintegrability to quasi-exact solvability: theory and application. This project aims to develop mathematical techniques to resolve longstanding problems in the area of integrability and exact solvability. Quantum integrable systems and exact solvable models are of central importance for understanding the correct behaviours of complex quantum problems without approximation. This project aims to construct sophisticated mathematical tools to settle key questions across a variety of models such as superintegrable systems, quantum spin chains, and spin-boson models. Anticipated applications of the proposed research include the accurate prediction of physical phenomena, from energy spectra to quantum correlations. Such advances should have significant ramifications, and provide benefits, well beyond the mathematical discipline itself.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220101094
Funder
Australian Research Council
Funding Amount
$431,900.00
Summary
Energy absorption and impact mechanics of origami structures and materials. This project aims to understand the dynamic behaviour of origami structures and metamaterials by utilising interdisciplinary approaches. This project expects to generate new knowledge in the areas of origami engineering and structural mechanics. The success of this project will form a foundation for studying energy absorption and impact mechanics of origami family; the fundamental physics and mechanics will be applied to ....Energy absorption and impact mechanics of origami structures and materials. This project aims to understand the dynamic behaviour of origami structures and metamaterials by utilising interdisciplinary approaches. This project expects to generate new knowledge in the areas of origami engineering and structural mechanics. The success of this project will form a foundation for studying energy absorption and impact mechanics of origami family; the fundamental physics and mechanics will be applied to characterise microstructures and design novel metamaterials and offer a way of exploring new materials with superior and tuneable performance. This should provide significant benefits to improvement of their safety, stability and reliability performance in applications such as vehicles, warships and offshore engineering.Read moreRead less