Rhinovirus impairs physiological and immunological lung development and causes exacerbation of allergic airways disease. Rhinovirus (RV) infections account for around 90 per cent of asthma exacerbations, yet the mechanisms behind this are unknown. This project will use mouse models to study the effects of early life RV infection and allergic sensitisation on respiratory and immunological development, with the expectation that early life RV infection disrupts anitgen presenting cell function.
When quantum is not desirable: quantum noise vs. quantum technologies. One of the key remaining obstacles to the successful deployment of quantum computers & sensors in science, industry, and society is the existence of noise sources that are themselves quantum, and thus have an unmatched potential for disruption. This project will attack this problem by providing (i) a detailed understanding of the impact of quantum noise sources, and developing protocols to (ii) characterize and (iii) overcome ....When quantum is not desirable: quantum noise vs. quantum technologies. One of the key remaining obstacles to the successful deployment of quantum computers & sensors in science, industry, and society is the existence of noise sources that are themselves quantum, and thus have an unmatched potential for disruption. This project will attack this problem by providing (i) a detailed understanding of the impact of quantum noise sources, and developing protocols to (ii) characterize and (iii) overcome the negative effects such realistic noise entails. In taking this necessary step for the implementation of these breakthrough technologies, it will not only significantly advance knowledge but will have a direct impact in the development of a technology in which Australia and other leading nations are heavily invested.Read moreRead less
From superintegrability to quasi-exact solvability: theory and application. This project aims to develop mathematical techniques to resolve longstanding problems in the area of integrability and exact solvability. Quantum integrable systems and exact solvable models are of central importance for understanding the correct behaviours of complex quantum problems without approximation. This project aims to construct sophisticated mathematical tools to settle key questions across a variety of models ....From superintegrability to quasi-exact solvability: theory and application. This project aims to develop mathematical techniques to resolve longstanding problems in the area of integrability and exact solvability. Quantum integrable systems and exact solvable models are of central importance for understanding the correct behaviours of complex quantum problems without approximation. This project aims to construct sophisticated mathematical tools to settle key questions across a variety of models such as superintegrable systems, quantum spin chains, and spin-boson models. Anticipated applications of the proposed research include the accurate prediction of physical phenomena, from energy spectra to quantum correlations. Such advances should have significant ramifications, and provide benefits, well beyond the mathematical discipline itself.Read moreRead less
Fluid properties and chaotic dynamics in equilibrium and nonequilibrium states. Over the last decade a revolution has been taking place in nonequilibrium statistical mechanics [Physics Today, Sept, 2002]. This revolution is characterized by adapting the mathematical theory of chaos to nonequilibrium statistical mechanics. Fundamental new theorems and algorithms for computing transport coefficients have been derived. The CIs have played a key role in this revolution. We seek to broaden these dev ....Fluid properties and chaotic dynamics in equilibrium and nonequilibrium states. Over the last decade a revolution has been taking place in nonequilibrium statistical mechanics [Physics Today, Sept, 2002]. This revolution is characterized by adapting the mathematical theory of chaos to nonequilibrium statistical mechanics. Fundamental new theorems and algorithms for computing transport coefficients have been derived. The CIs have played a key role in this revolution. We seek to broaden these developments by: generalizing a theorem which relates transport coefficients to chaoticity; detailed studies of the influence of thermostatting mechanisms on nonequilibrium chaoticity and fluctuations, and by understanding the range of applicability of a nonequilibrium fluctuation theorem for non-isoenergetic systems.Read moreRead less
Functionally Graded Ultra High Perfomance Concete Structure under Flexure. This project aims to develop a novel multilayer functionally graded concrete structure that is a mixture of normal strength concrete and ultra high performance concrete with the mixing ratio varying in a layer-wise manner, offering a highly cost-effective structural design solution with significantly improved safety and durability over conventional concrete structures. The expected outcomes include the innovative design, ....Functionally Graded Ultra High Perfomance Concete Structure under Flexure. This project aims to develop a novel multilayer functionally graded concrete structure that is a mixture of normal strength concrete and ultra high performance concrete with the mixing ratio varying in a layer-wise manner, offering a highly cost-effective structural design solution with significantly improved safety and durability over conventional concrete structures. The expected outcomes include the innovative design, experimental data on the static and dynamic structural behaviour, development of reliable simulation techniques and optimal design procedures for the proposed structure with greatly reduced material costs. The project will have huge benefits to Australian civil engineering industry and national economy.
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Heisenberg-limited lasers: building the revolution. The project aims to design and build a revolutionary new type of laser based on the ground-breaking 2020 Nature Physics paper by the two Chief Investigators. The significance of this work is that it overturns 60 years of theory about the limits to laser coherence, by applying 21st century quantum theory and quantum technology to the problem. This project expects to greatly advance the theory and, by instigating a collaboration with world-leadin ....Heisenberg-limited lasers: building the revolution. The project aims to design and build a revolutionary new type of laser based on the ground-breaking 2020 Nature Physics paper by the two Chief Investigators. The significance of this work is that it overturns 60 years of theory about the limits to laser coherence, by applying 21st century quantum theory and quantum technology to the problem. This project expects to greatly advance the theory and, by instigating a collaboration with world-leading experimentalists working with superconducting quantum devices, to demonstrate a laser with coherence beyond what was thought possible. Benefits of the project should flow from the manifold applications for highly coherent radiation, including scaling up superconducting quantum computing.Read moreRead less
Ultimate quantum limits to coherence. This project aims to discover the ultimate quantum limits to optical coherence. Quantum physics underpin the miniaturisation of technology, and quantum devices can do things better, often with vastly fewer resources, than conventional devices. Lasers underpin most modern optical technologies, and have been studied for decades, but the ultimate quantum limits are unknown. To find them, this project will use theoretical techniques that have not hitherto been c ....Ultimate quantum limits to coherence. This project aims to discover the ultimate quantum limits to optical coherence. Quantum physics underpin the miniaturisation of technology, and quantum devices can do things better, often with vastly fewer resources, than conventional devices. Lasers underpin most modern optical technologies, and have been studied for decades, but the ultimate quantum limits are unknown. To find them, this project will use theoretical techniques that have not hitherto been combined. This project will likely influence the long-term development of lasers and other quantum devices and underpin innovation in miniaturised optical technology and other quantum devices, leading ultimately to commercial products that yield a better quality of life.Read moreRead less
Systematically model the large-scale complexity of turbulent floods and thin film flows. This project continues development of new models, and computer
simulation, of turbulent flood, river and estuarine flow. The models
will be based systematically upon established turbulence models to
resolve accurately the complex physical processes. The development of
new and robust computer models for thin layers of coating fluid will
aid many industrial processes. We also aim to provide correct ini ....Systematically model the large-scale complexity of turbulent floods and thin film flows. This project continues development of new models, and computer
simulation, of turbulent flood, river and estuarine flow. The models
will be based systematically upon established turbulence models to
resolve accurately the complex physical processes. The development of
new and robust computer models for thin layers of coating fluid will
aid many industrial processes. We also aim to provide correct initial
conditions and boundary conditions for simpler cases of the above
flows. The approach leads to a greater understanding of the range of
applicability of the models through better estimating the errors in the
modelling process. The project develops a fundamental enabling
methodology for engineering and the sciences.
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Dissipation and relaxation in statistical mechanics. This project studies the mathematical conditions for relaxation either to equilibrium or to steady states, which is important in predicting behaviour in diverse fields including climate modelling, materials science, nanotechnology and biology. Early career researchers will be involved in the project, gaining valuable skills in theory and simulation.
Investigation and optimisation of displacement ventilation and cooling systems. An accurate optimisation design tool for cooling and ventilation will be of considerable benefit to the Australian building/construction industry, and will lead to a reduction in energy consumption, thereby reducing both consumer costs and Australia's total greenhouse gas output, as well as providing Australian industry with a competitive advantage. Turbulence modelling for stratified fluids is one of the grand chall ....Investigation and optimisation of displacement ventilation and cooling systems. An accurate optimisation design tool for cooling and ventilation will be of considerable benefit to the Australian building/construction industry, and will lead to a reduction in energy consumption, thereby reducing both consumer costs and Australia's total greenhouse gas output, as well as providing Australian industry with a competitive advantage. Turbulence modelling for stratified fluids is one of the grand challenge areas of science, and graduate students and postdoctoral researchers trained in this area will be well placed to make a significant contribution to the new technologies needed to address the major environmental problems currently being faced.Read moreRead less