Development and implementation of biodiversity information for sustainable management of South Australian groundwater. Clean potable water is one of the most important resources for human health and a successful economy. Increasingly, subterranean aquifers are used for storage and recovery of water. These aquifers contain dynamic ecosystems, but little is known about species composition or about the importance of the presence of various species for water quality. We will use the latest laborator ....Development and implementation of biodiversity information for sustainable management of South Australian groundwater. Clean potable water is one of the most important resources for human health and a successful economy. Increasingly, subterranean aquifers are used for storage and recovery of water. These aquifers contain dynamic ecosystems, but little is known about species composition or about the importance of the presence of various species for water quality. We will use the latest laboratory techniques and DNA identification methods to provide a template for determining ground water diversity and food web dynamics throughout Australia. This project will lead to a better understanding of how to manage ground water in a sustainable manner.Read moreRead less
The characterisation of wastewater distribution patterns for the production of decision support systems for pathogenic risk analysis in water catchments. The project will aim to collate data and map base-level distribution patterns of molecular and microbial markers of human sewage and natural/agricultural contamination with reference to diurnal and seasonal fluctuations. These data will then be used to develop decision support systems that predict contaminant dispersion and identify high-risk c ....The characterisation of wastewater distribution patterns for the production of decision support systems for pathogenic risk analysis in water catchments. The project will aim to collate data and map base-level distribution patterns of molecular and microbial markers of human sewage and natural/agricultural contamination with reference to diurnal and seasonal fluctuations. These data will then be used to develop decision support systems that predict contaminant dispersion and identify high-risk contamination sources. The diurnal collection of data is expected to show significant variations in the measured parameters associated with time of day, light intensity and temperature. Mapping of the sewage and nutrient loads throughout the year will provide base line data for identifying potential hotspots for targeting system upgrades or improved management programs.Read moreRead less
Synthetic Biology Derived Electroactive Whole Cell Microbial Biosensors. The aim of this project is to develop, using synthetic biology, electrically integrated microbial biosensors for the detection of heavy metals in the environment. Building on our existing technology, this project aims to produce novel ‘biobricks’ capable of electrically integrating electric microbes into real time environmental monitors for heavy metal contaminants. This expansion of synthetic biology, and integration of el ....Synthetic Biology Derived Electroactive Whole Cell Microbial Biosensors. The aim of this project is to develop, using synthetic biology, electrically integrated microbial biosensors for the detection of heavy metals in the environment. Building on our existing technology, this project aims to produce novel ‘biobricks’ capable of electrically integrating electric microbes into real time environmental monitors for heavy metal contaminants. This expansion of synthetic biology, and integration of electric bacteria into sensor systems, will result in a new platform technology that expands our abilities to protect the ecology, agriculture and health of terrestrial, marine and agricultural at risk areas from economic and environmental damage.Read moreRead less
Accelerated tailings remediation with plant and microbial biotechnologies. The Australian alumina industry produces 32 million tonnes of bauxite residue (alumina refining tailings) each year, most of which is stored in perpetuity in landfill-type tailings storage facilities. The high pH, high salinity, lack of plant nutrients, and poor physical properties of bauxite residue are major barriers to safe storage and successful closure of tailings storage facilities. Existing remediation approaches a ....Accelerated tailings remediation with plant and microbial biotechnologies. The Australian alumina industry produces 32 million tonnes of bauxite residue (alumina refining tailings) each year, most of which is stored in perpetuity in landfill-type tailings storage facilities. The high pH, high salinity, lack of plant nutrients, and poor physical properties of bauxite residue are major barriers to safe storage and successful closure of tailings storage facilities. Existing remediation approaches are expensive, slow, and often ineffective. We will deliver new microbial- and plant-driven biotechnologies for rapid, cost-effective remediation of bauxite residue. This will enable safe, sustainable closure of storage facilities, and safeguard the strong contribution of this $15 billion industry to Australia's economy. Read moreRead less
Microbial Pathogens as Selective Agents in the Evolution of Arthropod Sociality. We will reveal ecological and evolutionary forces that have shaped a major response of social insects to microbial disease, then apply the results to drug discovery. We will generate the first data on a new approach to antibiotic bioprospecting in the social insects yielding two major outcomes: First, we identify novel sources of antimicrobial compounds. Second, we demonstrate that the new, biorational approach is a ....Microbial Pathogens as Selective Agents in the Evolution of Arthropod Sociality. We will reveal ecological and evolutionary forces that have shaped a major response of social insects to microbial disease, then apply the results to drug discovery. We will generate the first data on a new approach to antibiotic bioprospecting in the social insects yielding two major outcomes: First, we identify novel sources of antimicrobial compounds. Second, we demonstrate that the new, biorational approach is a potent tool for natural product pharmaceutical bioprospecting. Both outcomes contribute directly to the National Research Priority Goal for the Sustainable Use of Australia's Biodiversity by developing new ways to find and identify novel natural resources.
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Adaptive ecotyping of the toxic cyanobacterium Cylindrospermopsis raciborskii to predict its invasive capacity. We change the world while other organisms adapt to these new conditions. Cyanobacteria (blue green algae) increasingly dominate water bodies that were previously free of these harmful blooms. To minimise the spread of these algae, this project will study the genetic basis that determines how rapidly they can evolve and adapt to a changing planet.