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Using Novel Causal Inference Approaches To Improve Decision-making In Infectious Diseases Epidemiology
Funder
National Health and Medical Research Council
Funding Amount
$76,365.00
Summary
Health care professionals face challenges in infectious diseases(ID) treatment and control from rapid spread of drug-resistant pathogens. Most evidence has come from randomised clinical trials (RCT); however, these are expensive to run, and their generalisability has been questioned. Causal inference methods are available to address this issue, but the uptake of these methods in ID has been limited. This study aims to utilise these epidemiological modelling to enhance the quality of future RCTs.
The Association Between Disability Acquisition, Socio-economic Disadvantage And Health: A Longitudinal Analysis Of Trajectories Of Disability
Funder
National Health and Medical Research Council
Funding Amount
$92,539.00
Summary
People with disabilities are more likely to live in disadvantaged circumstances and experience poorer health and wellbeing than people without disabilities. The aim of my research is to contribute a nuanced, causally-robust longitudinal analysis of the relationships between disability, socio-economic disadvantage and health. I will model disability trajectories to characterise the diversity of disability experiences over time, and the determinants and consequences of different trajectories.
Networks Analysis - Modelling Transmission Of Disease And Propagation Of Adverse Health Outcomes Through Interconnected Populations
Funder
National Health and Medical Research Council
Funding Amount
$120,253.00
Summary
Networks analysis is a powerful suite of statistical techniques that will be used to develop simulations of disease and poor health outcomes through an Australian injecting drug user network, a Laos/Vietnam based cohort of men who have sex with men (MSM) and the 2009 H1N1 influenza cohort. Development of robust predictive models of disease and health outcomes provides novel opportunities for identifying and developing finely targeted intervention and harm-minimisation strategies.
Gender As A Determinant Of Health – Consolidating The Evidence Base. An Analysis Of Gender Equity And Health Outcomes In Lower Income Countries, With A Focus On Maternal And Neonatal Mortality
Funder
National Health and Medical Research Council
Funding Amount
$122,714.00
Summary
Gender has been cited as a powerful influence on the extent and distribution of adverse health outcomes, especially maternal and neonatal mortality. It has been suggested that global health and development targets cannot be reached without adequate attention to gender equity. A strong evidence base is vital if gender is to be meaningfully considered in the post-2015 agenda. This thesis aims to extend this evidence base.
The National Notifiable Diseases Surveillance System, 1991-2011: Epidemiologic Analysis Of The First 20 Years Of National Infectious Diseases Notifications In Australia
Funder
National Health and Medical Research Council
Funding Amount
$181,154.00
Summary
The National Notifiable Diseases Surveillance System contains approximately 4 million records of infectious disease notifications made since 1991. We will use these data to describe trends in notifiable infectious diseases in Australia, determine the impact of interventions such as immunisation, and develop algorithms to identify infectious disease outbreaks as early as possible. This information will be used to help minimise the burden of infectious diseases in Australia in the future.
Individual Patient Data Meta-analysis Of Randomised Control Trials In Fluid Resuscitation
Funder
National Health and Medical Research Council
Funding Amount
$85,027.00
Summary
I am a registered nurse focused in critical care research. I have an interest in the area of fluid resuscitation. My aim is to carry out an individual patient data meta-analysis (IPDMA) on randomised controlled trials (RCTs) in fluid resuscitation. The IPDMA will consist of two of the largest critical care trials; Saline Vs Albumin fluid Evaluation (SAFE) study and the Crystalloid Vs Starch (CHEST) study, to add further evidence to the currently limited fluid resuscitation literature.
A Geographic Approach To Measuring Social Deprivation And Health Care Need For Primary Health Care Policy And Planning
Funder
National Health and Medical Research Council
Funding Amount
$148,213.00
Summary
Understanding how and where people use and access health services, and how social disadvantage affects this is important for planning and providing primary health care services. Presenting information as maps is an effective way to explore and communicate these issues. This research program will use a geographic and map-based approach to understanding patterns of health service use and social disadvantage, to assist in developing primary health care policy.
This project aims to comprehensively evaluate the role of androgen receptor (AR) signalling in breast cancer by identifying changes in AR signalling and its role in an endocrine resistant setting. Understanding the changes in AR signalling in either treatment-naive or treatment-resistant context would better assist in the identification for opportunities to modulate AR signalling as a therapeutic target in breast cancer.
Exploring Knowledge Translation In Indigenous Primary Health Care
Funder
National Health and Medical Research Council
Funding Amount
$93,741.00
Summary
New knowledge is needed about how to implement effective interventions and strengthen Indigenous primary health care systems. This study will explore how new knowledge gets implemented (or doesnÍt), for whom, and under what circumstances in Indigenous primary health care contexts. It will be the first study to look at how evidence, context and facilitation elements influence the implementation of research into Indigenous primary health care practice and policy.