Assessing development: designing better indices of poverty and gender equity. Contributing to development worldwide, this research raises Australia`s global standing and helps fulfil the values and responsibilities of the Australian people. It strengthens the basis for gender-related and poverty-related policy development and service delivery within Australia and helps correct the current over-emphasis, in measuring domestic gender inequity, on the more privileged women.
Because severe poverty ....Assessing development: designing better indices of poverty and gender equity. Contributing to development worldwide, this research raises Australia`s global standing and helps fulfil the values and responsibilities of the Australian people. It strengthens the basis for gender-related and poverty-related policy development and service delivery within Australia and helps correct the current over-emphasis, in measuring domestic gender inequity, on the more privileged women.
Because severe poverty and radically unequal gender relations burden many of our South East Asian and Pacific neighbours, development aid remains an important plank of our foreign policy. By providing better tools for measuring poverty and gender inequity, this project can improve our understanding of our region and augment the impact of our aid.Read moreRead less
The Ethical Responsibilities of Consumers. This project will explore the responsibilities of individuals with respect to the wrongful harms that occur in producing the goods and services that they consume. It examines the grounds and stringencies of such alleged responsibilities. It develops detailed case studies of three consumer products, coffee, mobile phones, and paper and cardboard, that present consumers with distinct ethical challenges, and evaluates ethical purchasing, consumer boycotts, ....The Ethical Responsibilities of Consumers. This project will explore the responsibilities of individuals with respect to the wrongful harms that occur in producing the goods and services that they consume. It examines the grounds and stringencies of such alleged responsibilities. It develops detailed case studies of three consumer products, coffee, mobile phones, and paper and cardboard, that present consumers with distinct ethical challenges, and evaluates ethical purchasing, consumer boycotts, and consumer activism as potential strategies for consumers to discharge their corresponding responsibilities. Read moreRead less
Ethical and Social Issues in Translating Epigenetics into Antenatal Care. This project aims to investigate how knowledge about the intergenerational transmission of health and disease is shaping antenatal care in Australia. It expects to generate new knowledge about how the science of epigenetics can be used to address social inequality and is anticipated to have impact across the social sciences, bioethics and public health. Expected outcomes of the project include novel theoretical approaches ....Ethical and Social Issues in Translating Epigenetics into Antenatal Care. This project aims to investigate how knowledge about the intergenerational transmission of health and disease is shaping antenatal care in Australia. It expects to generate new knowledge about how the science of epigenetics can be used to address social inequality and is anticipated to have impact across the social sciences, bioethics and public health. Expected outcomes of the project include novel theoretical approaches to the ethics of pregnancy, along with guidance tools to shape the use of epigenetics in antenatal care and social policy to reduce social inequalities. This should provide significant benefits, improving information and support available to vulnerable women as they negotiate maternal health and social services. Read moreRead less
Protecting while they prosper? Organisational responses to whistleblowing. This project aims to examine the adequacy of organisational responses to whistleblowing (employee reporting of wrongdoing). So far, research into public-interest whistleblowing has revealed much about the incidence, significance and experience of whistleblowers. This project now extends the research to the other side of the issue — the organisations. By comparing employee and managerial experience in multiple public and p ....Protecting while they prosper? Organisational responses to whistleblowing. This project aims to examine the adequacy of organisational responses to whistleblowing (employee reporting of wrongdoing). So far, research into public-interest whistleblowing has revealed much about the incidence, significance and experience of whistleblowers. This project now extends the research to the other side of the issue — the organisations. By comparing employee and managerial experience in multiple public and private sector organisations in Australia and New Zealand, the project intends to identify the factors that influence good and bad responses across a range of institutions; provide a clearer basis for reform of policies, procedures and law; and set benchmarks for comparative research worldwide.Read moreRead less
Regulating Autologous Stem Cell Therapies in Australia. This project aims to develop an ethical and regulatory framework for the use of autologous adult stem cell therapies in Australia. These therapies are increasingly being offered to patients for diseases and conditions that lack scientific evidence of safety and efficacy. This study aims to address this problem using a mixed methods approach to generate empirical data and theoretical, ethical and legal insights that will guide the responsibl ....Regulating Autologous Stem Cell Therapies in Australia. This project aims to develop an ethical and regulatory framework for the use of autologous adult stem cell therapies in Australia. These therapies are increasingly being offered to patients for diseases and conditions that lack scientific evidence of safety and efficacy. This study aims to address this problem using a mixed methods approach to generate empirical data and theoretical, ethical and legal insights that will guide the responsible development, translation and regulation of innovative stem cell therapies in Australia and internationally. Anticipated outcomes will improve patient advocacy and public knowledge about adult stem cell therapies, and facilitate better relationships between patients, researchers and clinicians.Read moreRead less
The Structure of Moral Reasoning: Hume, Kant and the Evidence from Psychopathology and Neuroscience. What can moral philosophers hope to learn from the sciences of the mind? Recent work on the disorders of autism and psychopathy, has promised to reshape a longstanding philosophical debate between Kantians and Humeans on the role of empathy (sympathy) in moral thinking. This project will draw out the implications of a range of neuroscientific findings for key questions in moral theory and also co ....The Structure of Moral Reasoning: Hume, Kant and the Evidence from Psychopathology and Neuroscience. What can moral philosophers hope to learn from the sciences of the mind? Recent work on the disorders of autism and psychopathy, has promised to reshape a longstanding philosophical debate between Kantians and Humeans on the role of empathy (sympathy) in moral thinking. This project will draw out the implications of a range of neuroscientific findings for key questions in moral theory and also consider how the normative and conceptual claims made by such theories, about what must be true of a moral judgment, are connected to descriptive claims about the psychology of the moral agents who make them.Read moreRead less
Environmental Justice and the Making of Just Food and Energy Policy. This project aims to improve two key areas of environmental policy by investigating the meaning of environmental justice and how it is best implemented. It will generate a significant new framework of the idea of environmental justice and offer innovative research that demonstrates what hinders and enables just policies in practice. Expected outcomes of this project include an updated and enhanced theory of environmental justic ....Environmental Justice and the Making of Just Food and Energy Policy. This project aims to improve two key areas of environmental policy by investigating the meaning of environmental justice and how it is best implemented. It will generate a significant new framework of the idea of environmental justice and offer innovative research that demonstrates what hinders and enables just policies in practice. Expected outcomes of this project include an updated and enhanced theory of environmental justice, a new understanding of the enablers and barriers to its implementation in practice, and recommendations to make policies on urban food security and energy transition more just. Overall, the project should provide the benefit of the development of more just policies on two key environmental issues facing Australia.Read moreRead less
Environmental Influences In The Establishment Of The Epigenetic Landscape In Children
Funder
National Health and Medical Research Council
Funding Amount
$695,097.00
Summary
The DNA in each of our cells does not exist alone, it is packaged into complex structures called chromosomes, through association with many different proteins. The distribution of these proteins varies along the length of a chromosome depending on the type of cell and this phenomenon is called 'epigenetics', literally meaning 'above the DNA'. Epigenetic analysis is the study of how proteins and other molecules can change the activity of a gene without changing the DNA sequence. All of our cells ....The DNA in each of our cells does not exist alone, it is packaged into complex structures called chromosomes, through association with many different proteins. The distribution of these proteins varies along the length of a chromosome depending on the type of cell and this phenomenon is called 'epigenetics', literally meaning 'above the DNA'. Epigenetic analysis is the study of how proteins and other molecules can change the activity of a gene without changing the DNA sequence. All of our cells use epigenetic changes to help control how they grow and develop. Evidence suggests a direct link between diet and environmental influences on our epigenetic profile. Recent research has traced the origins of many of the health problems of adult life back to the earliest periods of development _ to the time spent in the womb and the first few years of life. If we are born with a low birth weight, we are more likely to get sick later in life. Overwhelming evidence exists that the environment in the womb is critical for a healthy birth weight (and health in later life) and it is thought that epigenetics may be the missing link between this environment, low birth weight, and therefore health in later life. In addition, mounting evidence supports a general link between epigenetic de-regulation and predisposition to disease. However, the timing and the overall contribution of environmental- genetic influences to the establishment of faulty epigenetic markings remain largely unknown. Twins are the best model to study this link as they share similar (but not identical environments) and some share identical genetic makeup. Using twins, Dr Jeffrey Craig and his team will investigate the factors in the prenatal environment that modify specific cells, leading to low birth weight and increase disease risk later in life. They predict that this occurs via specific changes in gene activity caused by epigenetic disruption.Read moreRead less
Applying search theory for eradicating invasive species. Invasive species have major economic and environmental impacts in Australia and are a major cause of extinctions worldwide. Monitoring is crucial for the timely control of invasive species in sensitive environments. Early detection increases the probability of eradication and increased accuracy in detection reduces the impact of control programs on non-target species. Efficient monitoring also is crucial in determining whether eradication ....Applying search theory for eradicating invasive species. Invasive species have major economic and environmental impacts in Australia and are a major cause of extinctions worldwide. Monitoring is crucial for the timely control of invasive species in sensitive environments. Early detection increases the probability of eradication and increased accuracy in detection reduces the impact of control programs on non-target species. Efficient monitoring also is crucial in determining whether eradication has succeeded. Search Theory has been applied for over 60 years in a wide range of non-biological monitoring problems, resulting in large increases in target detection rates. Gains of a similar magnitude in invasive species detection would greatly enhance Australia's capacity to manage these threats.Read moreRead less
Improving external validity of stated choice experiments. This project aims to deliver more accurate estimates of choice behaviour by reducing biases due to choice task complexity in surveys as well as design artefacts. Extracting 'true' preferences is challenging, not only due to possible hypothetical bias, but also due to increasingly complex choice tasks and the existence of design artefacts. This project will investigate the latter two in the context of marketing, transport, health, and envi ....Improving external validity of stated choice experiments. This project aims to deliver more accurate estimates of choice behaviour by reducing biases due to choice task complexity in surveys as well as design artefacts. Extracting 'true' preferences is challenging, not only due to possible hypothetical bias, but also due to increasingly complex choice tasks and the existence of design artefacts. This project will investigate the latter two in the context of marketing, transport, health, and environmental economics, and proposes new methodologies to extract preferences that more closely reflect true behaviour in real markets.Read moreRead less