Gamete-specific knockout of Fizzy-Related to examine its meiotic role in oocytes and sperm. Fizzy-Related is a gene that appears to be essential in making an ovulated egg, and it may also have an important role to play in making sperm. A mouse knockout will be generated to examine exactly how it functions; because it affects the egg number remaining in the ovary and egg quality Fizzy-Related may be eventually an important therapeutic target.
Discovery Early Career Researcher Award - Grant ID: DE120101242
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Regulation of germ cell number and quality by Fizzy-related protein. Females have a limited supply of eggs in their ovaries and it appears that the Fizzy-related gene (FZR1) is important in making sure this full complement is gained. By using novel mouse knockouts of the FZR1 gene, the project will determine how this protein functions at the earliest stages of egg development.
Characteristics, trends, co-admissions and service needs of women admitted to residential parenting services in the year following giving birth in New South Wales. This project will examine the physical, psychological and demographic characteristics of women who use the residential parenting services provided by Tresillian and Karitane in New South Wales in twelve months following giving birth. Findings from this project will inform the design and delivery of health services to better meet the n ....Characteristics, trends, co-admissions and service needs of women admitted to residential parenting services in the year following giving birth in New South Wales. This project will examine the physical, psychological and demographic characteristics of women who use the residential parenting services provided by Tresillian and Karitane in New South Wales in twelve months following giving birth. Findings from this project will inform the design and delivery of health services to better meet the needs of women into the future.Read moreRead less