Co-design and dynamic mission optimisation of hypersonic flight vehicles. This project aims to deliver fundamental knowledge by integrating the modelling and control with the design of next generation hypersonic platforms. In an era where Australia's national security reliance on geographic isolation and support from allied forces are being challenged, the research outcomes of this project will play an important role in understanding the capabilities of hypersonic systems. The project will also ....Co-design and dynamic mission optimisation of hypersonic flight vehicles. This project aims to deliver fundamental knowledge by integrating the modelling and control with the design of next generation hypersonic platforms. In an era where Australia's national security reliance on geographic isolation and support from allied forces are being challenged, the research outcomes of this project will play an important role in understanding the capabilities of hypersonic systems. The project will also have significant spillover benefits into other complex system domains, where computational tools can be used to aid in design leading to high embedded-IP products for Australian industry. Furthermore, the proposal encompasses a strong research training aspect, with graduates exposed to leading edge industry and academia.Read moreRead less
Improving the efficiency of bovine oocyte maturation in vitro. For the dairy and beef industries, the hundreds of eggs (oocytes) in a high value cow's ovary that fail to produce a pregnancy are a wasted genetic resource. A key technology to unlocking this resource is in vitro maturation of oocytes, but the process is inefficient. One possible cause is that the current approaches to maturing oocytes in vitro do not adequately mimic the natural process in vivo. We will design new systems to matu ....Improving the efficiency of bovine oocyte maturation in vitro. For the dairy and beef industries, the hundreds of eggs (oocytes) in a high value cow's ovary that fail to produce a pregnancy are a wasted genetic resource. A key technology to unlocking this resource is in vitro maturation of oocytes, but the process is inefficient. One possible cause is that the current approaches to maturing oocytes in vitro do not adequately mimic the natural process in vivo. We will design new systems to mature cow oocytes in vitro by altering the chemical composition of maturation medium, thus improving the efficiency of laboratory embryo production and related technologies.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160101394
Funder
Australian Research Council
Funding Amount
$372,000.00
Summary
Early developmental influences on neocortical organisation. This project seeks to identify the influence of preceding developmental stages on the correct formation of the brain. Development is a sequence of transformations where every stage depends on the outcome of previous stages. The project intends to examine how the early sensory periphery, early-born brain circuits, and intrinsic neuronal interactions affect the subsequent organisation of the cerebral cortex – a mammal-specific brain regio ....Early developmental influences on neocortical organisation. This project seeks to identify the influence of preceding developmental stages on the correct formation of the brain. Development is a sequence of transformations where every stage depends on the outcome of previous stages. The project intends to examine how the early sensory periphery, early-born brain circuits, and intrinsic neuronal interactions affect the subsequent organisation of the cerebral cortex – a mammal-specific brain region responsible for perception, motor planning and cognition. It expects to provide novel mechanistic and conceptual insights into the process of normal brain development and more general biological phenomena, such as development and evolution. It may also provide insights into several genetic and non-genetic causes of brain malformations.Read moreRead less
Protecting cereal grain development at high temperatures. This project aims to investigate new temperature-responsive factors that regulate cereal grain development to protect grain production under heat stress. The new research will leverage international collaborations with access to cutting-edge genetic and technological resources, and refine novel X-ray imaging techniques in Australia, to observe how temperature affects flower structure and function in barley and rice. Favourable mutations t ....Protecting cereal grain development at high temperatures. This project aims to investigate new temperature-responsive factors that regulate cereal grain development to protect grain production under heat stress. The new research will leverage international collaborations with access to cutting-edge genetic and technological resources, and refine novel X-ray imaging techniques in Australia, to observe how temperature affects flower structure and function in barley and rice. Favourable mutations that optimise plant yield and fitness will be defined and explored in other, more complex, cereals such as wheat. Expected outcomes will be fundamental breakthroughs in understanding how plants respond to, and buffer, the effects of heat to lead to translational breeding strategies that bolster grain yield.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0561030
Funder
Australian Research Council
Funding Amount
$441,100.00
Summary
Developmental Imaging Facility. This application seeks to establish a facility to undertake expression profiling in vertebrate tissues on a genomic scale and at the highest resolution. Undertaking large scale projects of this nature requires specialised robotics and dedicated infrastructure for microscopy and tissue preparation. This facility will be the first of its type in Australia will permit researchers to perform genomic scale in situ screens, many as part of large international initiative ....Developmental Imaging Facility. This application seeks to establish a facility to undertake expression profiling in vertebrate tissues on a genomic scale and at the highest resolution. Undertaking large scale projects of this nature requires specialised robotics and dedicated infrastructure for microscopy and tissue preparation. This facility will be the first of its type in Australia will permit researchers to perform genomic scale in situ screens, many as part of large international initiatives in developmental and cellular biology. This large-scale, high-resolution expression profiling infrastructure is required to maintain international competitiveness and will dramatically improve our gene discovery, functional assessment and understanding of vertebrate development.Read moreRead less
Reducing Blackout Risk through Live Modelling and Monitoring. This project aims to reduce the risk of blackouts through the development of on-line systems for modelling and monitoring of loads and power system controllers. This project is a collaboration with Transgrid, Powerlink, Vencorp and ElectraNetSA, four Transmission companies renowned for innovation in the area of system stability. The project proposes to develop innovative algorithms and to implement these algorithms using advanced hard ....Reducing Blackout Risk through Live Modelling and Monitoring. This project aims to reduce the risk of blackouts through the development of on-line systems for modelling and monitoring of loads and power system controllers. This project is a collaboration with Transgrid, Powerlink, Vencorp and ElectraNetSA, four Transmission companies renowned for innovation in the area of system stability. The project proposes to develop innovative algorithms and to implement these algorithms using advanced hardware, software and communication systems to dynamically generate decision tools for safe and efficient power system operating conditions. These systems will also generate alarms if any risky operational situations arise.Read moreRead less
Nanosampling sensors for real-time embryo monitoring. The health potential of every individual is established early in life, during the period when the oocytes mature and embryos are formed. This project will develop a photonic sensing platform capable of monitoring embryos as they develop, which will lead to new insight into the earliest stages of life and improved assisted reproduction technologies.
Special Research Initiatives - Grant ID: SR0566924
Funder
Australian Research Council
Funding Amount
$52,825.00
Summary
Develop and pilot an e-cohort research technique for longitudinal studies using multiple international cohorts. The aim of this project is to develop and pilot an e-cohort research methodology suitable for longitudinal studies with multiple international cohorts. Historically, studies of this nature are expensive as they are conducted in traditional paper-based mode and the studies are therefore confined to one country. Population-based epidemiological studies of this type have led to major scie ....Develop and pilot an e-cohort research technique for longitudinal studies using multiple international cohorts. The aim of this project is to develop and pilot an e-cohort research methodology suitable for longitudinal studies with multiple international cohorts. Historically, studies of this nature are expensive as they are conducted in traditional paper-based mode and the studies are therefore confined to one country. Population-based epidemiological studies of this type have led to major scientific advances in global health for the last sixty years. Developing and employing e-research techniques in longitudinal studies will significantly reduce the costs of this important research and enable multi-national cohorts of participants that will result in high quality research.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC150100019
Funder
Australian Research Council
Funding Amount
$4,571,797.00
Summary
ARC Training Centre for Liquefied Natural Gas Futures. ARC Training Centre for Liquefied Natural Gas Futures. This training centre aims to deliver projects and training to enable future Australian Liquefied Natural Gas (LNG) production from reserves in deep water, at small or remote on-shore locations, with greater efficiency, less environmental impact, and at lower cost than currently possible. This should be accomplished via research projects undertaken by the PhD students and research fellows ....ARC Training Centre for Liquefied Natural Gas Futures. ARC Training Centre for Liquefied Natural Gas Futures. This training centre aims to deliver projects and training to enable future Australian Liquefied Natural Gas (LNG) production from reserves in deep water, at small or remote on-shore locations, with greater efficiency, less environmental impact, and at lower cost than currently possible. This should be accomplished via research projects undertaken by the PhD students and research fellows with guidance from the centre’s industrial partners. The centre’s expected legacy is a unique research and training facility, designed for future integration into a microscale LNG plant. The anticipated research and training outcomes will help to ensure Australia plays a leading role in future global LNG developments.Read moreRead less
Why do only some exotics become invasive? Combining ecological and genomic approaches to address alternative hypotheses in a recent Australian weed. This project will specifically test alternative hypotheses about how weeds become invasive. As invasive weeds affect both agricultural and native ecosystems equally, research on understanding the mechanisms of weed invasion is critical. Outcomes will benefit Australia by allowing better prioritisation of management against exotic plants already i ....Why do only some exotics become invasive? Combining ecological and genomic approaches to address alternative hypotheses in a recent Australian weed. This project will specifically test alternative hypotheses about how weeds become invasive. As invasive weeds affect both agricultural and native ecosystems equally, research on understanding the mechanisms of weed invasion is critical. Outcomes will benefit Australia by allowing better prioritisation of management against exotic plants already in the country by providing predictive tools to estimate likelihood of spread. For formal Pest Risk Analysis by regulators (eg Biosecurity Australia), our project will provide genomic tools by which the potential weediness of a regulated plant can be assessed through genetic screening, and forms part of an international effort to identify 'weedy genes'. Read moreRead less