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Please take a few minutes to provide your input. The survey closes COB Friday 29 May 2026.
Complete the 5 min survey now by clicking on the link below.
Immunology And Pathogenesis Of Malaria: Basic And Translational Research
Funder
National Health and Medical Research Council
Funding Amount
$727,685.00
Summary
Malaria is one of the most serious infectious diseases of humanity, killing 1-2 million children annually. In order to develop effective vaccines and interventions, it is important to understand both the causes of fatality and how to develop immunity to the disease. This application will continue a very strong international track record in malaria research ranging from basic lab-based molecular studies through to commercial development and population based health studies and policy formulation.
I am a public health physician and medical parasitologist determining the mechanism of clinical immunity to malaria, and working on the development of vaccines and therapies against malaria.
Immunological Control Of Cysticercosis And Hydatid Disease
Funder
National Health and Medical Research Council
Funding Amount
$828,300.00
Summary
In this project the world’s most effective vaccines against diseases caused by parasites will be translated from the laboratory to the clinic. The vaccines prevent transmission of parasites from livestock animals to humans. During the next 5 years the vaccines will be produced on a large scale and evaluated in field trials. The products of this research program will make a major contribution to reducing the number of people suffering from parasitic cysts.
Immunological Prevention Of Cysticercosis And Hydatid Disease
Funder
National Health and Medical Research Council
Funding Amount
$802,685.00
Summary
Professor Lightowlers’ has developed the world’s most effective vaccines against diseases caused by parasites. The vaccines prevent transmission of parasites from livestock animals to humans. During the next 5 years the vaccines will be produced on a large scale and evaluated in field trials. The products of this research program will make a major contribution to reducing the number of people suffering from parasitic cysts.
I am an infectious diseases physician and virologist/immunologist focused on developing and testing vaccines against the AIDS virus. I intend to achieve this by advancing novel vaccine concepts that stimulate broad and potent immunity and evaluating these vaccines in rigorous laboratory models and then moving them towards clinical trials.
Pathogenic Flaviviruses: Molecular Mechanisms Of Disease, Host Response And Vaccines
Funder
National Health and Medical Research Council
Funding Amount
$697,209.00
Summary
The application is aimed at advancing our understanding of the viral and host processes determining outcome of infection with pathogenic flaviviruses (i.e. West Nile virus) to the level allowing most comprehensive design of effective vaccines and anti-viral drugs. One of the aims is also to develop novel viral delivery vectors for cancer therapy based on self-replicating RNA of an attenuated Australian strain of West Nile virus, Kunjin.
This an integrated program of basic research on antigen discovery and immune mechanisms, and preclinical research on novel vaccine platforms, formulations or delivery systems for the rational design and clinical testing of a next generation vaccine against malaria. This interdisciplinary research fosters strong national and international links and offers the potential for significant economic benefit to Australia.
B Cell Survival And Responsiveness In Health And Disease
Funder
National Health and Medical Research Council
Funding Amount
$664,584.00
Summary
I am an immunologist focused on identifying how B lymphocytes, the cells responsible for producing antibodies, survive and participate in immune responses within the body. I achieve this by using specially designed, genetically modified, mice that allow me to follow B lymphocytes within the body and identify their key genetic and external controls. My work is relevant to vaccine development as well as the control of certain autoimmune diseases and B lymphocyte cancers.