Tuning parallel applications on software-defined supercomputers. Supercomputers are used by many Australian industries and laboratories to make better products and perform critical predictions, and it is essential that codes operate efficiently. This project aims to assist programmers in identifying performance bottlenecks in their code quickly and easily. The project expects to supersede the current methods, which are often complex and time-consuming, by developing innovative software tools and ....Tuning parallel applications on software-defined supercomputers. Supercomputers are used by many Australian industries and laboratories to make better products and perform critical predictions, and it is essential that codes operate efficiently. This project aims to assist programmers in identifying performance bottlenecks in their code quickly and easily. The project expects to supersede the current methods, which are often complex and time-consuming, by developing innovative software tools and techniques. The expected outcomes include novel software, verified by industry partners in real world case studies, ranging from life sciences to hypersonic transport. This should provide significant benefits, including the capacity for Australian industries to access world-class supercomputing technology.Read moreRead less
Novel role of RNA methylation in neuronal homeostasis. This proposal is aimed at understanding the RNA signalling that takes place in neuronal homeostatic response. The crucial role of neuronal homeostasis for normal brain function is evidenced throughout the nervous system; however, the precise underlying mechanisms are still not well understood. The proposed research will utilise high-throughput sequencing approaches coupled with biochemical, molecular and cell biological assays to provide mec ....Novel role of RNA methylation in neuronal homeostasis. This proposal is aimed at understanding the RNA signalling that takes place in neuronal homeostatic response. The crucial role of neuronal homeostasis for normal brain function is evidenced throughout the nervous system; however, the precise underlying mechanisms are still not well understood. The proposed research will utilise high-throughput sequencing approaches coupled with biochemical, molecular and cell biological assays to provide mechanistic insights into the molecular processes that control neuronal homeostatic responses. This will elucidate how neural plasticity and network stability are maintained, a process that is critical for our understanding of sensory processing, learning and memory throughout life.Read moreRead less
Privacy-preserving data processing on the cloud. This project aims to address the current lack of privacy of user data processed by common cloud computing web servers, including email, business data, and confidential files. This project aims to develop new techniques in cryptography. The anticipated outcome is a suite of practical tools enabling common cloud computing processing operations such as search, statistical analysis, and multi-user access control, to be performed efficiently while pres ....Privacy-preserving data processing on the cloud. This project aims to address the current lack of privacy of user data processed by common cloud computing web servers, including email, business data, and confidential files. This project aims to develop new techniques in cryptography. The anticipated outcome is a suite of practical tools enabling common cloud computing processing operations such as search, statistical analysis, and multi-user access control, to be performed efficiently while preserving the data privacy. These tools should provide significant benefits to the privacy of cloud users, as well as financial and reputation benefits to the IT industry, by significantly reducing the likelihood of massive user data privacy breaches in the event of a cyber-hacking attack on the cloud server.Read moreRead less
How brains become lateralised. This project aims to understand how the left and right sides of the brain become specialised for different cognitive functions, a phenomenon called lateralisation. Lateralisation is one of the least understood organisational principles of the brain, yet is crucial to the way we think and behave. Manifested most clearly as handedness, the brain is lateralised for many cognitive tasks such as language, reasoning, memory and emotion. However, the developmental origin ....How brains become lateralised. This project aims to understand how the left and right sides of the brain become specialised for different cognitive functions, a phenomenon called lateralisation. Lateralisation is one of the least understood organisational principles of the brain, yet is crucial to the way we think and behave. Manifested most clearly as handedness, the brain is lateralised for many cognitive tasks such as language, reasoning, memory and emotion. However, the developmental origin and anatomical substrate of most cognitive asymmetries are unknown. This project will use a chick model of brain lateralisation to quantify and localise to specific brain circuits the patterns of differential gene expression that give rise to anatomical and functional asymmetries.Read moreRead less
Neural circuit control of effort under stress . This Project aims to investigate how the ‘decision’ to persist in exerting effort to obtain a reward is encoded in the the brain and affected by stress. This work will generate new knowledge on the neural mechanisms through which stress modifies neural activity to control decision making processes underpinning adaptive behaviours essential for survival. The expected outcomes of this work include enhanced capacity at the interface of behavioural a ....Neural circuit control of effort under stress . This Project aims to investigate how the ‘decision’ to persist in exerting effort to obtain a reward is encoded in the the brain and affected by stress. This work will generate new knowledge on the neural mechanisms through which stress modifies neural activity to control decision making processes underpinning adaptive behaviours essential for survival. The expected outcomes of this work include enhanced capacity at the interface of behavioural and computational neuroscience, that will in turn provide significant benefits through greater insight into brain functions essential for survival, with long ranging implications for performance optimisation and brain-inspired computing. Read moreRead less
Enabling Anonymity and Privacy for Blockchain Technology in a Quantum World. Blockchain is a promising technology in the digital world today. However, existing approaches for enabling blockchain applications, particularly with privacy protection and anonymity, are vulnerable to quantum computer attacks. This project aims to enable novel cryptographic mechanisms together with their cryptographic libraries for protecting blockchain in the quantum world, hence, post-quantum secure blockchain. The e ....Enabling Anonymity and Privacy for Blockchain Technology in a Quantum World. Blockchain is a promising technology in the digital world today. However, existing approaches for enabling blockchain applications, particularly with privacy protection and anonymity, are vulnerable to quantum computer attacks. This project aims to enable novel cryptographic mechanisms together with their cryptographic libraries for protecting blockchain in the quantum world, hence, post-quantum secure blockchain. The expected outcomes of this project include innovative technologies, as well as secure and practical post-quantum protocols for protecting future blockchain applications. This will provide economic and social benefits to Australian industry through the enablement of advanced technologies which are developed in Australia.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH200100009
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Research Hub for Transforming Energy Infrastructure Through Digital Engineering. This Research Hub will harness the strengths of data-based and physics-based sciences to transform the operation of Australia’s offshore energy infrastructure. This essential research will create, use and embed observations of past and ongoing activity to engineer tools and approaches necessary to enhance our understanding of the offshore environment, optimise critical operations for existing facilities (includi ....ARC Research Hub for Transforming Energy Infrastructure Through Digital Engineering. This Research Hub will harness the strengths of data-based and physics-based sciences to transform the operation of Australia’s offshore energy infrastructure. This essential research will create, use and embed observations of past and ongoing activity to engineer tools and approaches necessary to enhance our understanding of the offshore environment, optimise critical operations for existing facilities (including installation and maintenance), and efficiently design future infrastructure. The integrated multidisciplinary approach will not only help Operators achieve high productivity through low downtime and optimised maintenance, but also demonstrate, in research and industry, the transformative potential of digital engineering.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210100975
Funder
Australian Research Council
Funding Amount
$415,775.00
Summary
Architectured ceramics to combine strength, toughness, and complex shapes. This project aims to develop ceramics that are simultaneously strong and tough, and to form them into complex shapes without compromising their mechanical properties – major challenges in science and engineering. Inspired by the internal architectures that confer these advantages on natural hard materials, it will produce novel ceramics with rationally-designed, highly-controlled dense architectures by developing a fast, ....Architectured ceramics to combine strength, toughness, and complex shapes. This project aims to develop ceramics that are simultaneously strong and tough, and to form them into complex shapes without compromising their mechanical properties – major challenges in science and engineering. Inspired by the internal architectures that confer these advantages on natural hard materials, it will produce novel ceramics with rationally-designed, highly-controlled dense architectures by developing a fast, scalable and versatile light-based 3D–4D printing technique combined with discrete element modelling. Outcomes will be toughened ceramics and new knowledge on processing-architecture-performance relationships, with significant benefits for biomaterials, defence, transport, high-temperature and aerospace applications.Read moreRead less
Targeting TGF-beta proteins to control animal reproduction. This project aims to develop a suite of novel biologics to control fertility in female mammals. This project expects to demonstrate that targeting a single class of ovarian proteins will enhance or inhibit egg production. The expected outcomes of this project are to (1) transform the breeding of livestock animals, which should provide significant benefits to the agricultural industry, through increased herd/flock sizes, and (2) provide ....Targeting TGF-beta proteins to control animal reproduction. This project aims to develop a suite of novel biologics to control fertility in female mammals. This project expects to demonstrate that targeting a single class of ovarian proteins will enhance or inhibit egg production. The expected outcomes of this project are to (1) transform the breeding of livestock animals, which should provide significant benefits to the agricultural industry, through increased herd/flock sizes, and (2) provide a non-surgical method of contraception in companion/feral species, which should address the large unmet need for fertility control in these animals.
Read moreRead less