Establishing The Physiological And Sleep Disruption Characteristics Of Wind Farm Versus Traffic Noise Disturbances In Sleep
Funder
National Health and Medical Research Council
Funding Amount
$1,357,652.00
Summary
Good sleep is essential for normal daytime functioning and health. Wind farm noise includes audible and unusually low frequency sound components, including infrasound, that could potentially disturb sleep through chronic sleep disruption and/or insomnia. This project will, for the first time, directly evaluate the sleep and physiological disturbance characteristics of wind farm noise compared to traffic noise reproduced in a specialised and carefully controlled laboratory environment.
Discovering Novel Molecules That Regulate Axonal Degeneration.
Funder
National Health and Medical Research Council
Funding Amount
$588,622.00
Summary
The axon is the primary signaling component of every neuron and is essential for normal function. Axonal degeneration is a key early pathological hallmark of Alzheimer’s disease. We lack a basic understanding of molecules that regulate this process. Such knowledge is essential for the development of treatments and therapies for dementia and the preservation of healthy ageing. I aim to discover the molecules that regulate axonal degeneration and study their function.
New Strategies In The Treatment And Imaging Of Neurodegenerative Diseases
Funder
National Health and Medical Research Council
Funding Amount
$934,085.00
Summary
The treatment and diagnosis of brain diseases is one of society’s major challenges. To address these challenges, we need a better understanding of the molecular mechanisms involved in brain disease. We will develop innovative ways in which to probe disease progression, assess efficacy of treatment, and ultimately treat a wide range of brain disorders.
Multiple Sclerosis Therapy: Human Pluripotent Stem Cell-Derived Neural Precursor Cells
Funder
National Health and Medical Research Council
Funding Amount
$1,775,225.00
Summary
Treatments for Multiple Sclerosis (MS) often have unsatisfactory outcomes. The limited ability of the body to repair damaged nerve tissue highlights a critically important need for MS patients. The long-term goal of our research is to develop a stem cell-based therapy that halts disease progression and repairs damaged nerve tissue. Research efforts will refine techniques to make safe and clinically-compatible cells from human stem cell lines and verify the therapeutic activity of these cells.