Investigating Thermal And Possible Non-thermal Effects Of Radiofrequency Radiation In Brain Tissue
Funder
National Health and Medical Research Council
Funding Amount
$245,681.00
Summary
There are ongoing concerns over the possible harm from the prolonged use of mobile phone handsets. The WHO have issued a research agenda to address these concerns. This study aims to study possible mechanisms at the cellular level that was identified as a high priority research need. It aims to find out whether cellular changes that could be harmful follow as a result of slight heating effects within tissue, or whether some other, non-thermal, mechanisms may be involved.
Mobile Phones, Radiofrequency Exposure And The Development Of Cognitive Function In Primary School Children
Funder
National Health and Medical Research Council
Funding Amount
$551,477.00
Summary
Increasingly widespread exposure to radiofrequency fields from mobile telephones has raised concern about potential adverse health effects. The WHO has called for further research in children. We will conduct a 3 year study of 600 primary school students focussing on their exposure to mobile phones and cognitive development. If there are no significant effects, the community can be reassured. However if effects are demonstrated, we would need to restrict the use of mobile phones by children.
Noncontact Biventricular Mapping And Intramural Ablation In A Chronic Ovine Model Of Septal Ventricular Tachycardia
Funder
National Health and Medical Research Council
Funding Amount
$519,279.00
Summary
Ventricular tachycardia (VT), an abnormal rhythm originating from the bottom portion of the heart is the major cause of sudden death in the community. Medications are not reliably effective. Expensive (costing about $40,000 every 5 years) implanted defibrillators are very effective in terminating VT, but frequently require painful shocks. Patients who require frequent treatment from their defibrillators are considered for mapping and ablation. About half of the patients with VT have the arrhythm ....Ventricular tachycardia (VT), an abnormal rhythm originating from the bottom portion of the heart is the major cause of sudden death in the community. Medications are not reliably effective. Expensive (costing about $40,000 every 5 years) implanted defibrillators are very effective in terminating VT, but frequently require painful shocks. Patients who require frequent treatment from their defibrillators are considered for mapping and ablation. About half of the patients with VT have the arrhythmia originating from the septum (heart muscle separating the two bottom portions of the heart). This area of the heart is difficult to map from an electrical point of view. A new type of mapping system called the Ensite 3000 system enables acquisition of 3,300 virtual electrical signals from within a heart chamber using an electrode array that does not have to be in direct contact with the heart muscle surface. Our evaluation of the Ensite system in one chamber of the heart has found it to be very good in identifying areas of abnormal electrical activity. It is possible that simultaneous mapping from both sides of the septum using Ensite might be useful in mapping VT originating from the septum. Destruction of the abnormal area, once identified, is generally done using a catheter, but is limited by its ability to destroy targets deep in the heart tissue. We have designed and developed a catheter that is equipped with a needle at its tip that can create deeper lesions. In this study we will be evaluating mapping using the Ensite electrodes in both ventricles in a chronic sheep model with VT originating from the septum. The Ensite mapping will be validated with detailed contact (conventional) mapping. The prototype catheter will be used to destroy the site of origin of VT, once identified. This study should enable more effective treatment of patients with VT and improve their quality of life.Read moreRead less
Achieving More Effective Weight Loss With Intermittent Energy Restriction
Funder
National Health and Medical Research Council
Funding Amount
$1,373,874.00
Summary
Part of the difficulty in achieving lasting weight loss is that the body responds to dieting with compensatory changes in appetite, metabolic rate & blood hormone levels. We have shown in men that alternating phases of energy restriction with periods of greater food intake markedly improves weight loss by overcoming this “famine reaction”. This study will examine if the intermittent diet also produces more effective weight loss in women, and whether it is applicable to the wider community.
Novel nanostructured high energy cathode material. Recently, the demand for rechargeable batteries has exploded due to the enormous increase in the variety and number of miniaturized devices. It is expected that this demand for high capacity rechargeable batteries as energy sources will become even greater in the future. This program is focused to develop novel high performance cathode materials for lithium rechargeable batteries. The outcomes of the project will be of great benefit to develop ....Novel nanostructured high energy cathode material. Recently, the demand for rechargeable batteries has exploded due to the enormous increase in the variety and number of miniaturized devices. It is expected that this demand for high capacity rechargeable batteries as energy sources will become even greater in the future. This program is focused to develop novel high performance cathode materials for lithium rechargeable batteries. The outcomes of the project will be of great benefit to develop new class rechargeable batteries that are economical, lightweight, environmentlly benign and high energy.Read moreRead less
New Silent Anchors for Floating Offshore Wind Turbines in Calcareous Sand . Reliable wind energy sites are in deeper waters and require offshore floating structures to harness the wind energy. Such floating structures require a reliable anchoring system that is secure and environmentally friendly. Calcareous sands, rich in carbonate content, pose unique challenges with their behaviour difficult to predict. In this project, a novel silent anchoring system is investigated that can be installed wit ....New Silent Anchors for Floating Offshore Wind Turbines in Calcareous Sand . Reliable wind energy sites are in deeper waters and require offshore floating structures to harness the wind energy. Such floating structures require a reliable anchoring system that is secure and environmentally friendly. Calcareous sands, rich in carbonate content, pose unique challenges with their behaviour difficult to predict. In this project, a novel silent anchoring system is investigated that can be installed with minimum noise and vibration compared to more traditional counterparts. Through the state of the art development in numerical modelling and centrifuge modelling, this project will advance Australian Science and Practice in designing floating wind turbines in carbonate rich soils offshore and help energy transition.Read moreRead less
Advanced Nanostructured Ceramic Composites for Ultracapacitors. The global climate changes and the related disastrous events such as heat flows, bushfires, and flooding will endanger the Australian population and our natural environment. The implementation of effective devices and technologies to reduce our carbon footprint is a priority task. The project addresses the issue by development of new ultracapacitor materials for next generation green energy storage devices through engineering and im ....Advanced Nanostructured Ceramic Composites for Ultracapacitors. The global climate changes and the related disastrous events such as heat flows, bushfires, and flooding will endanger the Australian population and our natural environment. The implementation of effective devices and technologies to reduce our carbon footprint is a priority task. The project addresses the issue by development of new ultracapacitor materials for next generation green energy storage devices through engineering and implementation of advanced nanoceramics and nanocomposites created by innovative nanotechnologies. The project will also contribute to other national research priorities such as materials and frontier technologies, reduction of atmospheric pollution, and decrease in the energy dependence of our country on oil.Read moreRead less
Age- And Energy-status Dependent-plasticity Of Glucose Sensing, Orexigenic NPY Neurons: The Glucose-ghrelin Balance
Funder
National Health and Medical Research Council
Funding Amount
$578,641.00
Summary
Our research aims to identify how specific brain cells detect changes in glucose levels and how ageing and diet affect their function. We identified a subset of nerve cells that detect changes in glucose and the “hunger” hormone ghrelin, their ability to do so adapting with age and nutritional status. This project will investigate the potential of these nerve cells as targets for therapeutic and diet- intervention strategies to target obesity, diabetes and promote healthy ageing