Optimising Benefits And Minimising Potential Harms Of Obesity Treatments
Funder
National Health and Medical Research Council
Funding Amount
$707,370.00
Summary
This work aims to find safe and more effective obesity treatments for the over 2.1 billion people worldwide with overweight or obesity. Severely energy restricted diets are currently the most effective dietary obesity treatment, but these are underutilized due to concerns about potential harms. This work will investigate using severe diets intermittently rather than continuously, as a means of enhancing their benefits of long-term weight/fat loss while also reducing potential harmful effects.
High Protein, Low Glycemic Load Weight Loss Diets In Type 2 Diabetes
Funder
National Health and Medical Research Council
Funding Amount
$906,928.00
Summary
High protein, low glycemic load weight loss diets have the potential to be of value in long term weight control but there is little long term data available. There is also some uncertainty about the long term safety of high protein diets and this needs clarification in long term trials. As compliance to the diet is the major issue in long term trials we will explore new ways of getting people to stay in long term studies and maintain a calorie reduced diet.
Improving Weight Loss Outcomes By Minimizing Adaptive Responses To Energy Restriction
Funder
National Health and Medical Research Council
Funding Amount
$621,458.00
Summary
While losing excess weight reduces the risk of lifestyle diseases such as diabetes, current weight loss strategies are ineffective for most, in part because the body mounts a ‘famine reaction’ that increases hunger, decreases metabolic rate and may also cause loss of muscle and bone mass. This research aims to determine the effects of the famine reaction on body composition, as well as to identify new ways to block the famine reaction with food, thereby enabling more people to attain and maintai ....While losing excess weight reduces the risk of lifestyle diseases such as diabetes, current weight loss strategies are ineffective for most, in part because the body mounts a ‘famine reaction’ that increases hunger, decreases metabolic rate and may also cause loss of muscle and bone mass. This research aims to determine the effects of the famine reaction on body composition, as well as to identify new ways to block the famine reaction with food, thereby enabling more people to attain and maintain a healthy body weight and composition.Read moreRead less