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The Impact Of Using EHealth Interventions To Improve Health Behaviours Through Dietary And Lifestyle Management In Patients With Chronic Kidney Disease
Funder
National Health and Medical Research Council
Funding Amount
$37,657.00
Summary
People with chronic kidney disease, particularly those on haemodialysis, have complex dietary needs. The renal diet is an important part of treatment however it is often poorly adhered to. New methods to enhance patient education and their ability to manage their diet is needed. This research will evaluate the use of technology-based strategies to enhance patient care, particularly regarding their diet and lifestyle, with findings informing future practices in this area.
Acupause: A Randomised Single-blind Sham-controlled Trial Of Acupuncture For Postmenopausal Vasomotor Symptoms
Funder
National Health and Medical Research Council
Funding Amount
$129,182.00
Summary
I am a general practitioner with both Traditional Chinese Medicine and Medical Acupuncture qualifications. My research focuses on acupuncture's effectiveness in treating hot flushes after the menopause. In my study 360 women with hot flushes will be divided into two groups with one group receiving acupuncture and another group receiving "placebo" or "sham" acupuncture. We will compare number and severity of hot flushes in both groups at the end of the treatment period.
CAPLA Study: Catheter Ablation For Persistent Atrial Fibrillation. A Multicentre Randomised Study Of Pulmonary Vein Antral Isolation (PVAI) Alone Vs PVAI With Posterior Left Atrial Wall Isolation (PWI)
Funder
National Health and Medical Research Council
Funding Amount
$124,676.00
Summary
Atrial fibrillation (AF) is a common heart rhythm abnormality that affects quality of life with added health care costs. A minimally invasive procedure called catheter ablation (CA) is effective in controlling simple AF (paroxysmal AF) but the best ablation strategy to control a more resistant form of AF (Persistent AF) is unknown. This trial has been designed to address this key gap in knowledge by assessing if adding specific additional ablation to CA will improve outcomes.
Plasmapheresis As A Novel Treatment Of Postural Tachycardia Syndrome: A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$97,081.00
Summary
We aim to conduct a randomized controlled trial to test our hypothesis that the removal of autoantibodies (through plasmapheresis) will reduce the severity of symptoms in patients with postural tachycardia syndrome. We will be measuring symptom scores, cardiovascular fitness on exercise testing, heart rate and blood pressure responses during valsalva and orthostatic stress as well as the metabolic profiles and presence of autoantibodies in the blood of patients participating in the trial.
The PRECISE study is a double blind, randomised, placebo controlled trial comparing pregabalin in addition to usual care, to placebo in addition to usual care for the treatment of sciatica.
Improving The Understanding And Management Of Children Hospitalised With Bronchiolitis In Northern Australia
Funder
National Health and Medical Research Council
Funding Amount
$69,506.00
Summary
Acute bronchiolitis remains one of the most common serious lower respiratory tract infections. Children can be treated effectively at home; however many require hospitalisation and current treatment is essentially supportive with oxygen and fluid therapy. In Indigenous settings where high colonisation of bacteria and burden of respiratory disease exist, antibiotics such as azithromcyin may provide clinical improvement in the short term outcomes for those children hospitalised with bronchiolitis.
Hand Splinting And Motor Training In Cerebral Palsy
Funder
National Health and Medical Research Council
Funding Amount
$80,952.00
Summary
As many as 1 in 500 children have cerebral palsy or a brain injury. 1 in 3 cannot walk, 1 in 4 cannot talk, 3 in 4 are in pain. These conditions impact on a child's ability to use their hands to touch, play, draw and explore. Hand use is the single most important factor for determining a child's long term independence into adulthood. This project explores the most effective treatment approach to enable children to use their hands to reach the goals they want to achieve and live meaningful lives.
Does Metformin Have A Disease Modifying Effect In Symptomatic Knee Osteoarthritis? A Multicentre Randomised, Double-blind, Placebo-controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$124,676.00
Summary
Osteoarthritis(OA) is a major contributor to this disease burden. Currently, there is no therapy that slows disease progression. Metformin may affect OA progression via multiple pathways that address the pathogenesis of knee OA, including weight loss, glucose- and lipid-lowering, and anti-inflammation. This will be the world first randomised, double-blind controlled trial, to assess the effect of metformin, compared with placebo, on knee OA-related structural and clinical outcomes
This project will examine if providing additional therapy services on a Saturday reduces health care costs, and improves the health of hospital inpatients receiving rehabilitation compared to the usual Monday to Friday service. Preliminary information suggests additional Saturday rehabilitation services could reduce length of stay by 3 days without compromising discharge outcomes. If successful this trial will have substantial health and economic benefits for the patients and for organizations.
Modifying Cognitive Trajectories Using Computerised Cognitive Training
Funder
National Health and Medical Research Council
Funding Amount
$72,768.00
Summary
The "Use it or lose it" principal is highly applicable in cognition functions, particularly with ageing. This project aims to use an intervention that promotes active brain processes and function to protect and preserve it from deterioration. The effect of this dementia-prevention strategy and results will help fill gaps in the current body of knowledge, and will allow the prescription of individualised treatment by showing the mechanisms by which this intervention works to improve cognition.