Realistic models of permeation in ion channels. Ion channels are formed by proteins in cell membranes and provide pathways for fast and controlled flow of selected ions. This activity generates action potentials in nerves and muscles that forms the basis of all movement, sensation and thought processes. Recent determination of the crystal structure of channel proteins has enabled construction of models that can relate channel function to its structure--necessary for understanding their operati ....Realistic models of permeation in ion channels. Ion channels are formed by proteins in cell membranes and provide pathways for fast and controlled flow of selected ions. This activity generates action potentials in nerves and muscles that forms the basis of all movement, sensation and thought processes. Recent determination of the crystal structure of channel proteins has enabled construction of models that can relate channel function to its structure--necessary for understanding their operation and seeking cures for diseases caused by their malfunction. This project aims to develop accurate ion-protein-water interactions for permeation models based on stochastic and molecular dynamics simulations using both classical and quantum mechanical methods.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989648
Funder
Australian Research Council
Funding Amount
$350,000.00
Summary
Optical test-bed facility for mid infrared components for sensing, imaging and astrophotonics. This test facility will enable Australian researchers to validate optical components and technologies at wavelengths from 2.5 to 20 microns, that are crucial for a wide range of applications including biophotonics, sensing, imaging, defense, and astro-photonics. Technologies related to the Mid IR are
expected to have a significant impact on quality of life and global economy. It will enable Australi ....Optical test-bed facility for mid infrared components for sensing, imaging and astrophotonics. This test facility will enable Australian researchers to validate optical components and technologies at wavelengths from 2.5 to 20 microns, that are crucial for a wide range of applications including biophotonics, sensing, imaging, defense, and astro-photonics. Technologies related to the Mid IR are
expected to have a significant impact on quality of life and global economy. It will enable Australian researchers to achieve a major impact in many areas of Mid IR fundamental and applied science as well as industry sectors such as sensing, biophotonics, defence, health, bio-security and imaging. Read moreRead less