Coproantigen detection tests for diagnosis of intestinal parasitic nematode infection. The aim of this project is to develop new tests for detection of hookworm and Strongyloides, two common intestinal worm infections of humans. These tests offer the potential to replace current tests, namely stool microscopy and serodiagnosis, both of whose performance is unsatisfactory due to deficiencies in sensitivity, specificity and operator convenience. The tests will rely on monoclonal antibodies to dete ....Coproantigen detection tests for diagnosis of intestinal parasitic nematode infection. The aim of this project is to develop new tests for detection of hookworm and Strongyloides, two common intestinal worm infections of humans. These tests offer the potential to replace current tests, namely stool microscopy and serodiagnosis, both of whose performance is unsatisfactory due to deficiencies in sensitivity, specificity and operator convenience. The tests will rely on monoclonal antibodies to detect parasite products in stool. Such testing technology is amenable to configuration in a robust format, suitable for large-scale manufacture. Given the worldwide prevalence of these parasites, the tests will have a market potential of international significance.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH150100028
Funder
Australian Research Council
Funding Amount
$3,708,510.00
Summary
ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecu ....ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecules. The initial focus would be early diagnosis of disease and point-of-care drug testing for humans and animals, but the technology platform could be used to sample food and environmental toxins. The hub expects these disruptive technologies will make Australian biotechnology, diagnostics, veterinary, agribusiness and manufacturing firms globally competitive.Read moreRead less
Optimisation of cell culture and molecular typing for the characterisation of Cryptosporidium in water. Cryptosporidium is an important waterborne agent of diarrhoeal disease in people and animals. Improved methods for accurately detecting viable parasite stages recovered from water are a priority research need for the water industry. They are dependent upon improved in vitro cultivation procedures that can be combined with DNA-based assays for identifying species and strains of Cryptosporidi ....Optimisation of cell culture and molecular typing for the characterisation of Cryptosporidium in water. Cryptosporidium is an important waterborne agent of diarrhoeal disease in people and animals. Improved methods for accurately detecting viable parasite stages recovered from water are a priority research need for the water industry. They are dependent upon improved in vitro cultivation procedures that can be combined with DNA-based assays for identifying species and strains of Cryptosporidium and closely related protozoa recovered from freshwater. This project addresses these needs in a collaborative study between scientists at Murdoch University with expertise in both in vitro cultivation and genetic characterisation of Cryptosporidium, and scientists from two of the major water utilities in Australia.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH210100040
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC RESEARCH HUB FOR CONNECTED SENSORS FOR HEALTH. This Hub aims to develop, manufacture and deploy high-tech, cyber-secure, medically-certified IoT sensors to global health markets by integrating disparate Australian capabilities into a productive end-to-end value chain. This Hub expects to position Australia at the forefront of connected health by integrating sensor science with cyber-secure data analytics, regulatory approval and certified manufacturing capabilities. Expected outcomes of this ....ARC RESEARCH HUB FOR CONNECTED SENSORS FOR HEALTH. This Hub aims to develop, manufacture and deploy high-tech, cyber-secure, medically-certified IoT sensors to global health markets by integrating disparate Australian capabilities into a productive end-to-end value chain. This Hub expects to position Australia at the forefront of connected health by integrating sensor science with cyber-secure data analytics, regulatory approval and certified manufacturing capabilities. Expected outcomes of this Hub include advanced manufacturing capacity for connected sensors, strategic partnerships and commercialisation skills to translate sensors research to create economic benefits such as jobs and locally-made products for domestic and export markets, as well as improving the health of Australians.Read moreRead less
ARC Research Network on Intelligent Sensors, Sensor Networks and Information Processing. Sensor networks, a collection of diverse sensors interconnected via an ad-hoc communication network, are identified as one of the key technologies that over the next two decades will change the way we live. This research network brings together an interdisciplinary team of outstanding Australian researchers representing all the key disciplines required to successfully deploy sensor networks and links this te ....ARC Research Network on Intelligent Sensors, Sensor Networks and Information Processing. Sensor networks, a collection of diverse sensors interconnected via an ad-hoc communication network, are identified as one of the key technologies that over the next two decades will change the way we live. This research network brings together an interdisciplinary team of outstanding Australian researchers representing all the key disciplines required to successfully deploy sensor networks and links this team with the foremost international authorities and leading industry players in the area of sensor networks. This research network will guide collaborative research that will ensure Australia to play a world leading role in sensor network development and implementation.
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Energy-saving design: investigation of the thermal performance of rammed earth residential buildings. Housing people in Australian remote communities is energy intensive. This is particularly true in hot regions, where the house running costs are significant due to air-conditioning units functioning 24 hours a day, for most of the year. Rammed earth houses in dry-arid climate zones should not require any air-conditioning in summer. This project aims to investigate the optimal thermal performance ....Energy-saving design: investigation of the thermal performance of rammed earth residential buildings. Housing people in Australian remote communities is energy intensive. This is particularly true in hot regions, where the house running costs are significant due to air-conditioning units functioning 24 hours a day, for most of the year. Rammed earth houses in dry-arid climate zones should not require any air-conditioning in summer. This project aims to investigate the optimal thermal performance of two occupied houses using a novel sensor network. It aims to deliver new evidence on the thermal performance of rammed earth buildings to inform energy-efficiency decision frameworks and enhance the wellbeing of Indigenous communities in hot regions.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160101101
Funder
Australian Research Council
Funding Amount
$348,741.00
Summary
Single-Molecule Circuitry for Nanoscale Electronic Devices. The aim of this project is to develop novel methods for forming robust single-molecule circuitry. The use of single molecules in electronics represents the next level of miniaturisation of electronic components, which would enable us to meet the expanding demands of modern technologies and to continue the downscaling trend in electronic devices. This project aims to address the requirements needed to translate single-molecule electronic ....Single-Molecule Circuitry for Nanoscale Electronic Devices. The aim of this project is to develop novel methods for forming robust single-molecule circuitry. The use of single molecules in electronics represents the next level of miniaturisation of electronic components, which would enable us to meet the expanding demands of modern technologies and to continue the downscaling trend in electronic devices. This project aims to address the requirements needed to translate single-molecule electronics from its current status as a fundamental tool to real-world applications. Key approaches will be the use of surface chemistry to develop new methods of wiring single molecules and the integration of robust single-molecule junctions with semiconducting electrodes. The expected project outcomes pave the way for single-molecule electronic and analytical devices.Read moreRead less
Experiences of addiction, treatment and recovery: An online resource for members of the public, health professionals and policymakers. Alcohol and other drug addiction is a major health and social issue in Australia. Treatment success rates are modest and little is known about how people experience and manage addiction and the stigma that accompanies it. This project will generate new knowledge on alcohol and other drug addiction by applying a proven qualitative methodology to these issues for t ....Experiences of addiction, treatment and recovery: An online resource for members of the public, health professionals and policymakers. Alcohol and other drug addiction is a major health and social issue in Australia. Treatment success rates are modest and little is known about how people experience and manage addiction and the stigma that accompanies it. This project will generate new knowledge on alcohol and other drug addiction by applying a proven qualitative methodology to these issues for the first time. It will produce an effective, innovative online resource for affected Australians, their family and friends, and the wider Australian community including health professionals and policymakers.Read moreRead less
Thermodynamics inversion for mineral systems. This project aims to provide a newly developed science approach to the Australian Lithospheric Architecture Magnetotelluric Project (AusLAMP). AusLAMP provides unparalleled geophysical information aimed at unravelling the tectonic history of the Australian continent and its mineral potential. The project will use thermodynamically based geodynamic simulators to jointly analyse and quantify intraplate deformation. This will illuminate the cause of dri ....Thermodynamics inversion for mineral systems. This project aims to provide a newly developed science approach to the Australian Lithospheric Architecture Magnetotelluric Project (AusLAMP). AusLAMP provides unparalleled geophysical information aimed at unravelling the tectonic history of the Australian continent and its mineral potential. The project will use thermodynamically based geodynamic simulators to jointly analyse and quantify intraplate deformation. This will illuminate the cause of driving fluid flow thorough the lithosphere, mineralisation phenomena, their datasets and geometries, and dynamic aspects of the processes driving mineral systems.Read moreRead less
Developing the capacity to model the impact of interventions that target high-risk drinking among young Australians. Alcohol use is a major contributing factor to social and health problems among young Australians. The project will inform the development of effective policy by providing multidisciplinary research evidence and the capacity to model how various interventions impact on the prevalence of alcohol-related problems.