A Phase III Trial Comparing Adjuvant Versus Salvage Radiotherapy For High Risk Patients Post Radical Prostatectomy
Funder
National Health and Medical Research Council
Funding Amount
$819,138.00
Summary
About half of all patients Treated with an operation to remove their prostate cancer have a high chance of the cancer coming back. Giving immediate radiotherapy to all patients will improve cure rates but does not benefit all men and can cause significant side effects. This study explores whether it is safe to wait and only give radiotherapy when there is a rising PSA after surgery indicating active cancer. A total of 470 men from Australasia will enter this study comparing the two approaches.
Quality Improvement In Aboriginal Primary Health Care: Lessons From The Best To Better The Rest.
Funder
National Health and Medical Research Council
Funding Amount
$617,427.00
Summary
High performing primary health care (PHC) services are essential to "close the gap" in Aboriginal and Torres Strait Islander health outcomes. Little previous research has investigated the contextual factors around a particular service that influence the success of quality improvement initiatives. We aim to transfer knowledge about the processes that facilitate the success of quality improvement initiatives in these services whilst building research and evaluation capacity in the services.
The Healthy Brain Project: A Prospective Cohort Study To Examine How Later-life University Education May Affect The Trajectory Of Ageing-related Cognitive Decline
Funder
National Health and Medical Research Council
Funding Amount
$1,085,742.00
Summary
Previous research has indicated that higher levels of education in early adulthood are associated with lower risk for dementia in older adults. This world-first project will examine if older adults who undertake university education have reduced rates of age-related cognitive decline than older adults who do not undertake further education. This would support the notion that boosting cognitive reserve in later life is protective against age- and disease-related neurodegenerative change.
Improving Outcomes For People With Acute Mental Illness In The Emergency Department: A Data Linkage Study
Funder
National Health and Medical Research Council
Funding Amount
$251,470.00
Summary
Currently, there is a lack of integration between emergency and mental health information systems. This means it is difficult for clinicians to comprehensively understand a patient’s interaction with other services – an important aspect when making treatment decisions. Our study will link 5 years of information from health, police and national death databases. This will identify areas where emergency services can be improved for vulnerable people seeking help for their mental health problem.
CKD-FIX: A Randomised, Controlled Trial Of Allopurinol In The Slowing Of Kidney Disease Progression
Funder
National Health and Medical Research Council
Funding Amount
$1,917,147.00
Summary
Chronic kidney disease (CKD) is a major public health problem affecting over 1.5 million Australians and is associated with increased risk of death, heart disease and progression to end-stage kidney disease (ESKD). Current treatments to slow progression to ESKD are limited. The CKD-FIX trial aims to find out whether treatment with allopurinol, a commonly used drug for gout prevention, safely and effectively slows CKD progression. This could lead to significant health and economic benefits.