Cycle decompositions of graphs. The benefits to Australia of fundamental research in core disciplines such as mathematics are well documented. This project aims to solve long-standing and significant open problems in the field of mathematics known as graph theory. Solving such problems will undoubtedly bring Australian research in this field to the fore, and help to enhance Australia's international research profile generally. The project offers substantial postgraduate training in the form of t ....Cycle decompositions of graphs. The benefits to Australia of fundamental research in core disciplines such as mathematics are well documented. This project aims to solve long-standing and significant open problems in the field of mathematics known as graph theory. Solving such problems will undoubtedly bring Australian research in this field to the fore, and help to enhance Australia's international research profile generally. The project offers substantial postgraduate training in the form of three excellent PhD projects in discrete mathematics. The computer age has ensured that this is a booming discipline and an increasing component of undergraduate syllabi around the world. It is thus a crucial area in which to be providing quality research training.Read moreRead less
Emerging applications of advanced computational methods and discrete mathematics. Ongoing improvements in computer performance are revolutionising research in combinatorial discrete mathematics, and leading to exciting new applications in information technology and the biological and chemical sciences. As a result, substantial international research effort, both at universities and in commercial and industrial organisations, is being channelled into high-performance computation and theoretical p ....Emerging applications of advanced computational methods and discrete mathematics. Ongoing improvements in computer performance are revolutionising research in combinatorial discrete mathematics, and leading to exciting new applications in information technology and the biological and chemical sciences. As a result, substantial international research effort, both at universities and in commercial and industrial organisations, is being channelled into high-performance computation and theoretical problems in combinatorial mathematics. Our aim is to develop and apply advanced computational methods through the study of several unsolved theoretical problems in design theory and practical problems in exact matrix computation and drug design.Read moreRead less
Algorithms and computation in four-dimensional topology. This project will establish Australia as a world leader in computational topology, particularly in the all-important areas of topology in three and four dimensions. In four dimensions this work will be truly groundbreaking; until now the field has seen little development due to the complexity of the algorithms and computations required, and the applicant is in the unique position of having the necessary tools to make significant progress ....Algorithms and computation in four-dimensional topology. This project will establish Australia as a world leader in computational topology, particularly in the all-important areas of topology in three and four dimensions. In four dimensions this work will be truly groundbreaking; until now the field has seen little development due to the complexity of the algorithms and computations required, and the applicant is in the unique position of having the necessary tools to make significant progress in a feasible time frame. In three dimensions this project will strengthen the distinguished computational topology community in Melbourne, led by pioneers such as Rubinstein, Goodman, Hodgson as well as the applicant himself.Read moreRead less
Geometric partial differential systems and their applications. This proposal addresses questions central to the understanding of nonlinear partial differential systems from classical, quantum field theory and liquid crystals. Applications to physical problems such as the Yang-Mills flow, Faddeev's model and liquid crystal systems are of great interest and importance in the broader scientific community. The project will yield internationally significant results in theoretical mathematics, with ....Geometric partial differential systems and their applications. This proposal addresses questions central to the understanding of nonlinear partial differential systems from classical, quantum field theory and liquid crystals. Applications to physical problems such as the Yang-Mills flow, Faddeev's model and liquid crystal systems are of great interest and importance in the broader scientific community. The project will yield internationally significant results in theoretical mathematics, with applications in physics and and other sciences. Specialist training will be provided for Australia's next generation of mathematicians. This project will enable Australian researchers to stay at the forefront of research in this area, strengthening links with a number of world-leading mathematicians.Read moreRead less
Geometric variational problems and nonlinear partial differential systems. We will investigate several important problems on non-linear partial differential systems, bridging analysis, differential geometry and mathematical physics. Harmonic maps are the prototype of maps minimizing the Dirichlet energy. The liquid crystal configuration generalizes the harmonic map with values into two dimensional spheres. The Yang-Mills equations originated from particle physics. We will make fundamental contri ....Geometric variational problems and nonlinear partial differential systems. We will investigate several important problems on non-linear partial differential systems, bridging analysis, differential geometry and mathematical physics. Harmonic maps are the prototype of maps minimizing the Dirichlet energy. The liquid crystal configuration generalizes the harmonic map with values into two dimensional spheres. The Yang-Mills equations originated from particle physics. We will make fundamental contributions to these topics: Regularity problem and energy minimality of weakly harmonic maps, Weak solutions of the liquid crystal equilibrium system, Yang-Mills heat flow and singular Yang-Mills connections.
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Macdonald polynomials: Combinatorics and representations. This proposal is part of the aim to build a world class research team in algebraic combinatorics and combinatorial representation theory at the University of Melbourne, led by the two CI.
These fields are currently experiencing very rapid growth and development, and a strong Australia based team will further enhance the country's strong reputation in combinatorics and algebra.
The project will also provide a perfect training ground fo ....Macdonald polynomials: Combinatorics and representations. This proposal is part of the aim to build a world class research team in algebraic combinatorics and combinatorial representation theory at the University of Melbourne, led by the two CI.
These fields are currently experiencing very rapid growth and development, and a strong Australia based team will further enhance the country's strong reputation in combinatorics and algebra.
The project will also provide a perfect training ground for Higher Degree Students with interests in pure mathematics as well as computer
algebra and symbolic computation.Read moreRead less
New computational methods study on protein function prediction. The proposed research aims to develop new computational methods to solve one of the most important bioinformatics problems in the post-genome era. This project will expand the knowledge on protein sequence-structure-function relationship, provide new analysis methods and predict the functions of novel proteins. This project will strengthen Australia's reputation for research excellence.
Statistical Methods for Discovering Ribonucleic acids (RNAs) contributing to human diseases and phenotypes. Identifying the causative genetic factors involved in quantitative phenotypes and diseases is a major goal of biology in the 21st century and beyond. A crucial step towards this goal is identifying and classifying the functional non-protein-coding Ribonucleic acids (RNAs) encoded in the human genome. This project will make major contributions to international efforts in this area by identi ....Statistical Methods for Discovering Ribonucleic acids (RNAs) contributing to human diseases and phenotypes. Identifying the causative genetic factors involved in quantitative phenotypes and diseases is a major goal of biology in the 21st century and beyond. A crucial step towards this goal is identifying and classifying the functional non-protein-coding Ribonucleic acids (RNAs) encoded in the human genome. This project will make major contributions to international efforts in this area by identifying RNA molecules that contribute to quantitative phenotypes including susceptibility to disease. As such, it will directly benefit fundamental science via the discovery and classification of new molecules. Indirectly, it will lead to breakthroughs in biology, and consequently to major medical and pharmaceutical advances in the diagnosis and treatment of genetic disease.Read moreRead less
Quantum entanglement and its role in complex quantum systems. Quantum entanglement - non-classical correlations in quantum states - is the physical resource at the heart of modern applications of quantum technology, such as absolutely secure communication, and teleportation of quantum states from one location to another. This project aims to deepen our theoretical understanding of entanglement by characterizing the type and amount of entanglement present in the ground and thermal states of a ge ....Quantum entanglement and its role in complex quantum systems. Quantum entanglement - non-classical correlations in quantum states - is the physical resource at the heart of modern applications of quantum technology, such as absolutely secure communication, and teleportation of quantum states from one location to another. This project aims to deepen our theoretical understanding of entanglement by characterizing the type and amount of entanglement present in the ground and thermal states of a general physical system. These results will enable us to study the central role entanglement plays in quantum phase transitions - the change of a physical system from one state of matter to another, different, state of matter, one with a truly quantum character.Read moreRead less
Multi-scale modelling of cell migration in developmental biology. Interpretative and predictive tools are needed for the comprehensive understanding of directed cell migration in the medical sciences. Mathematical models and modelling methodologies developed in this project will make a significant contribution to the investigation of cell migration and the testing and generation of hypotheses. Such models are needed to understand observed cellular patterns. This project will contribute to knowle ....Multi-scale modelling of cell migration in developmental biology. Interpretative and predictive tools are needed for the comprehensive understanding of directed cell migration in the medical sciences. Mathematical models and modelling methodologies developed in this project will make a significant contribution to the investigation of cell migration and the testing and generation of hypotheses. Such models are needed to understand observed cellular patterns. This project will contribute to knowledge of normal and abnormal developmental processes, especially in embryonic growth. Understanding these processes should lead to prediction and treatment of congenital disorders and contribute to a healthy start to life.Read moreRead less