Implementation Of A New, Inexpensive And High-throughput Matrix Assisted Laser Desorption / Ionization _ Time Of Flight Mass Spectrometry Test For Superior Detection Of Fragile X Syndrome In Targeted Diagnostics And Newborn Population Screening.
Funder
National Health and Medical Research Council
Funding Amount
$254,175.00
Summary
Background: The Fragile X Syndrome (FXS) is the most common form of inherited intellectual disability. There are now a number of treatments for FXS. However, often this disorder is not clearly recognized. We have developed a novel FXS test that could resolve this issue. Our objective is to develop a commercial package that describes suitability of our test for diagnostic use. If successful this could potentially leading to improvement in the prognosis for FXS children through early treatment int ....Background: The Fragile X Syndrome (FXS) is the most common form of inherited intellectual disability. There are now a number of treatments for FXS. However, often this disorder is not clearly recognized. We have developed a novel FXS test that could resolve this issue. Our objective is to develop a commercial package that describes suitability of our test for diagnostic use. If successful this could potentially leading to improvement in the prognosis for FXS children through early treatment intervention.Read moreRead less
Population Outcomes And Cost-effectiveness Of Universal Newborn Hearing Vs Risk Factor Screening At Age 5 Years.
Funder
National Health and Medical Research Council
Funding Amount
$540,423.00
Summary
Universal newborn hearing screening (UNHS) is being widely implemented because it is thought to greatly improve outcomes for children with congenital deafness. However, it is also very costly. Between 2003-5, all New South Wales babies were offered UNHS, while Victorian babies were offered a risk-factor screening and referral program. This two-year 'natural experiment' paves the way for a unique population effectiveness and cost-effectiveness study of UNHS as the children reach 5 years of age.
A Glint Or A Squint Should Make You Think! A Randomised, Controlled Study To Determine The Impact Of An Eye-health Awareness Program For New Parents
Funder
National Health and Medical Research Council
Funding Amount
$95,348.00
Summary
Retinoblastoma (RB) is a rare, blinding and sometimes fatal, childhood eye cancer. The earliest diagnosis affords the child the best prognosis for retaining their sight, eye or their life. This project will examine parents’ current understanding of the symptoms and signs for RB, identify barriers to early diagnosis of RB, and to develop, implement and evaluate a sustainable public health awareness program to potentially improve the timing of diagnosis and subsequent outcomes for this disease.
Discovery Early Career Researcher Award - Grant ID: DE230100704
Funder
Australian Research Council
Funding Amount
$426,816.00
Summary
Reframing knowledge of preconception lifestyles: A socioecological approach. This project aims to reframe our understanding of women’s preconception lifestyle health using a novel, socioecological approach. This project expects to generate new knowledge on societal views of weight stigma for preconception women and identify policy stakeholders’ views on integrating preconception into healthy lifestyle policies. Expected outcomes of this project include a new theory- and evidence-informed concept ....Reframing knowledge of preconception lifestyles: A socioecological approach. This project aims to reframe our understanding of women’s preconception lifestyle health using a novel, socioecological approach. This project expects to generate new knowledge on societal views of weight stigma for preconception women and identify policy stakeholders’ views on integrating preconception into healthy lifestyle policies. Expected outcomes of this project include a new theory- and evidence-informed conceptual model for preconception lifestyle health that transcends the current focus on personal responsibility. This should provide significant benefits, such as informing policy to drive systems changes around preconception lifestyle health with concomitant cultural benefits to Australians, leading to improved population health.Read moreRead less
Evaluating Cancer Screening: Context, Evidence, Values And Ethics
Funder
National Health and Medical Research Council
Funding Amount
$572,460.00
Summary
The research and clinical communities are divided over whether certain forms of cancer screening do more harm than good. This project asks: What is the right thing to do about cancer screening now? Using robust qualitative methodologies, we will study real cases of cancer screening and analyse their ethical implications. Drawing on this data and analysis, we will produce tools to help policy-makers, consumers and professionals make good decisions about cancer screening in future.
Advanced Non-invasive Cardiovascular Risk Screening In The Community: Practical And Cost Effective?
Funder
National Health and Medical Research Council
Funding Amount
$287,321.00
Summary
This research focuses on the practicalities and cost of mobile, advanced, non-invasive cardiovascular assessments to determine the extent of CVD and clinical risk factors and its likely impact on patterns of treatment and care to “disadvantaged” individuals living in rural and remote regions and Indigenous Australians. The advantage of directly acquiring risk profile information has not been fully explored and its potential to address an “epidemic” of CVD world-wide cannot be overstated.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453801
Funder
Australian Research Council
Funding Amount
$102,900.00
Summary
Asia/Pacific HIV/AIDS Database: Support for Regional Policy Research. HIV/AIDS is one of the greatest contemporary threats to global human security, and its rapid growth in parts of the Asia/Pacific region makes it a major concern for Australia. Appropriate responses to the threat require accurate and regularly updated policy information. The construction of an interactive HIV policy data bank will support considerable research in a number of disciplines directly relevant to HIV control. This pr ....Asia/Pacific HIV/AIDS Database: Support for Regional Policy Research. HIV/AIDS is one of the greatest contemporary threats to global human security, and its rapid growth in parts of the Asia/Pacific region makes it a major concern for Australia. Appropriate responses to the threat require accurate and regularly updated policy information. The construction of an interactive HIV policy data bank will support considerable research in a number of disciplines directly relevant to HIV control. This project draws on multiple sources to construct a research and policy tool which will be drawn on by the partner organizations in a variety of HIV-related research projects.
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Reforming evidence synthesis and translation for food and nutrition policy. This project aims to develop and evaluate a ‘Fit-for-Purpose’ framework to strategically guide evidence synthesis and translation for food and nutrition policies in order to effectively and safely tackle contemporary nutrition and food security problems. The project intends to use interdisciplinary approaches that integrate nutrition science, health promotion and policy science. The project would also examine policy-make ....Reforming evidence synthesis and translation for food and nutrition policy. This project aims to develop and evaluate a ‘Fit-for-Purpose’ framework to strategically guide evidence synthesis and translation for food and nutrition policies in order to effectively and safely tackle contemporary nutrition and food security problems. The project intends to use interdisciplinary approaches that integrate nutrition science, health promotion and policy science. The project would also examine policy-maker acceptance of the framework. Expected project outcomes include an enhanced capacity to critically analyse existing policies and guide future food and nutrition policy formulation and evaluation. This project would provide significant benefits by helping to promote public health, wellbeing and food system sustainability.Read moreRead less
Strengthening community responses to hepatitis B. Australians who have been born overseas often have high rates of chronic hepatitis B. In this project people with hepatitis B and people who provide them with health and social services will be interviewed to understand individual responses to the infection, and to identify barriers to effective health care delivery.
Citizens' juries: enabling effective influenza pandemic policy through engagement with the community. The project will provide information and practical guidance to assist with South Australian pandemic management specifically and will have implications for the state and national disaster planning generally. The project will provide resources for both state and national policy makers in the form of technical reports and comprehensive public health information modules appropriate for disseminatio ....Citizens' juries: enabling effective influenza pandemic policy through engagement with the community. The project will provide information and practical guidance to assist with South Australian pandemic management specifically and will have implications for the state and national disaster planning generally. The project will provide resources for both state and national policy makers in the form of technical reports and comprehensive public health information modules appropriate for dissemination to the wider Australian community. The project will contribute to increased community awareness of pandemic influenza and enhanced community acceptance of (and cooperation with) pandemic management plans while establishing a mechanism for future pandemic and disaster policy planning and evaluation.Read moreRead less