Health and resilience in the preschool years: An innovative approach to early intervention. Given the prevalence of psychopathology in childhood, it is essential that we maximise the effectiveness of early intervention (EI). Drawing on theory and research highlighting the marked influence, on cognitive and socio-emotional development, of particular kinds of parent-child discussions about past experiences, this project aims to foster preschooler's achievement of key developmental tasks (emergent ....Health and resilience in the preschool years: An innovative approach to early intervention. Given the prevalence of psychopathology in childhood, it is essential that we maximise the effectiveness of early intervention (EI). Drawing on theory and research highlighting the marked influence, on cognitive and socio-emotional development, of particular kinds of parent-child discussions about past experiences, this project aims to foster preschooler's achievement of key developmental tasks (emergent literacy, emotion knowledge, attachment) by training parents and children in effective conversational styles. The research will (i) develop an innovative, theoretically-driven approach to EI, (ii) test this approach in clinical and nonclinical populations, and (iii) provide a strong test of social interaction theories of development.Read moreRead less
Identifying risk markers for depression: A cognitive neuroscience approach. This project will establish objective markers for detecting early signs of depression. These markers are crucial in enabling early intervention to limit the course of depression. They will also benefit the development of prevention strategies, since they provide a means to identify high risk individuals. Currently there exists no simple and objective test or set of markers that can detect the early signs of depression. T ....Identifying risk markers for depression: A cognitive neuroscience approach. This project will establish objective markers for detecting early signs of depression. These markers are crucial in enabling early intervention to limit the course of depression. They will also benefit the development of prevention strategies, since they provide a means to identify high risk individuals. Currently there exists no simple and objective test or set of markers that can detect the early signs of depression. The available tests provide information relevant to the later-stage of clinical depression only. In this regard, non-invasive and objective markers are urgently required to limit the burden of depression. In Australia, $3.3 billion in productivity and 12 million working days are lost each year as a result of depression.Read moreRead less
Gene-brain pathways in emotional brain stability and instability. Emotional instability is a defining trait of major mental illnesses. The ability to identify individuals susceptible to emotional instability will be important in limiting the burden of disease from these illnesses. Mental conditions cost the Australian economy approximately $14.9 bill p/a, and depression will be the second leading contributor to burden of disease by 2020. The project will provide the first evidence for the combin ....Gene-brain pathways in emotional brain stability and instability. Emotional instability is a defining trait of major mental illnesses. The ability to identify individuals susceptible to emotional instability will be important in limiting the burden of disease from these illnesses. Mental conditions cost the Australian economy approximately $14.9 bill p/a, and depression will be the second leading contributor to burden of disease by 2020. The project will provide the first evidence for the combination of gene-brain-behaviour markers which best capture emotional instability versus resilience. This evidence base will be crucial to developing new tools and strategies for early intervention, and ultimately prevention, for these conditions of mental health.Read moreRead less
An Integrative Theory of Flashback Memories. Flashback memories are a core phenomenon in a range of psychological disorders. People who have suffered trauma, for example, experience a sense of reliving the past. This project will conduct the first comprehensive analysis of flashbacks by building on existing theories of autobiographical memory and applying convergent methodologies to study flashbacks. The project will assess the content, retrieval mode, and the brain mechanisms underpinning fl ....An Integrative Theory of Flashback Memories. Flashback memories are a core phenomenon in a range of psychological disorders. People who have suffered trauma, for example, experience a sense of reliving the past. This project will conduct the first comprehensive analysis of flashbacks by building on existing theories of autobiographical memory and applying convergent methodologies to study flashbacks. The project will assess the content, retrieval mode, and the brain mechanisms underpinning flashbacks. These data will lead to the first empirically-driven model of flashbacks that encompasses the psychological and neural bases of flashbacks. This model will advance our understanding of cognitive processes underpinning many psychological disorders.Read moreRead less
Trauma and Unwanted Memories. Post Traumatic Stress Disorder (PTSD) is a potentially debilitating condition that affects survivors of trauma. Intrusive memories of the trauma is the key problem in people with PTSD. This project will attempt to understand intrusive memories and will clarify why these memories persist. Outcomes from this project will directly assist people with PTSD because it will enhance understanding of a key symptom that maintains the disorder.
Cognitive control in obsessive-compulsive disorder. Obsessive-compulsive disorder is associated with significant social and economic burden. There is a pressing need to understand the cognitive mechanisms that drive and maintain this disorder. This research will permit exciting advances that will extend existing models of OCD by (1) elucidating the effects of different strategies for responding to obsessional thoughts,(2) integrating psychological, cognitive, and neuropsychological models of OCD ....Cognitive control in obsessive-compulsive disorder. Obsessive-compulsive disorder is associated with significant social and economic burden. There is a pressing need to understand the cognitive mechanisms that drive and maintain this disorder. This research will permit exciting advances that will extend existing models of OCD by (1) elucidating the effects of different strategies for responding to obsessional thoughts,(2) integrating psychological, cognitive, and neuropsychological models of OCD, (3) developing innovative approaches to intrusive thoughts that will benefit the treatment of OCD and (4) shaping the research directions of future Australian researchers. Read moreRead less
Understanding and predicting the role of memory in depression recurrence. Depression exerts an immense social and economic burden on the community. There is an urgent need to understand the factors that increase vulnerability to recurrence. This project will have 5 key benefits; it will: (i) extend theoretical models of depression, (ii) aid the identification of individuals at risk of relapse, (iii) guide the development of evidence-based relapse prevention programs (meeting National Research Pr ....Understanding and predicting the role of memory in depression recurrence. Depression exerts an immense social and economic burden on the community. There is an urgent need to understand the factors that increase vulnerability to recurrence. This project will have 5 key benefits; it will: (i) extend theoretical models of depression, (ii) aid the identification of individuals at risk of relapse, (iii) guide the development of evidence-based relapse prevention programs (meeting National Research Priority 2), (iv) enhance Australia's reputation for conducting cutting-edge experimental clinical research, and (v) shape the research directions of upcoming Australian researchers. The findings will inform policymakers who determine mental health service provision to the Australian community.Read moreRead less
Models of adolescent drug use and its consequences. Recent concerns surround the impact of drug abuse - particularly binge drinking, inhalant abuse and cannabis use - on the mental health of adolescents. Early drug use is associated with mental health problems although the mechanisms involved are not well characterised. The present proposal aims to use animal models to characterise substance abuse that occurs during the adolescent period and to investigate its effects on brain and behaviour. Inc ....Models of adolescent drug use and its consequences. Recent concerns surround the impact of drug abuse - particularly binge drinking, inhalant abuse and cannabis use - on the mental health of adolescents. Early drug use is associated with mental health problems although the mechanisms involved are not well characterised. The present proposal aims to use animal models to characterise substance abuse that occurs during the adolescent period and to investigate its effects on brain and behaviour. Increasing our knowledge of the causes and consequences of adolescent drug abuse will improve Australia's ability to confront this problem and to develop early interventions and treatments that minimise associated harms.Read moreRead less
Regulating anger: Cognitive reappraisal, emotional suppression, and post-event rumination. Australians bear the substantial psychological, social, and economic costs associated with unrestrained anger. Anger problems are associated with school and work difficulties, poor social relationship quality, alcohol and drug use, financial and legal difficulties, premature cardiovascular mortality, and clinically significant mental health problems. Anger and aggression also cause much harm to society th ....Regulating anger: Cognitive reappraisal, emotional suppression, and post-event rumination. Australians bear the substantial psychological, social, and economic costs associated with unrestrained anger. Anger problems are associated with school and work difficulties, poor social relationship quality, alcohol and drug use, financial and legal difficulties, premature cardiovascular mortality, and clinically significant mental health problems. Anger and aggression also cause much harm to society through crime, domestic abuse, and workplace violence among others. The Australian Institute of Criminology estimates the cost of assault, sexual assault, and homicide in Australia at over $2.5 billion per year. The insights gained from this research may help ameliorate these negative consequences of anger.Read moreRead less
Problem Gambling: Can Subtle Physiological Reactions To Wins And Losses Help Identify The Problem Gambler? Problem gambling is a major public health issue affecting 3%-6% of the adult population with the Productivity Commission (1999) detailing many associated consequences including major depression, suicide, substance abuse, marital and familial dysfunction and domestic violence. Problem gambling also has deleterious, long term effects on the mental and physical health of partners and children. ....Problem Gambling: Can Subtle Physiological Reactions To Wins And Losses Help Identify The Problem Gambler? Problem gambling is a major public health issue affecting 3%-6% of the adult population with the Productivity Commission (1999) detailing many associated consequences including major depression, suicide, substance abuse, marital and familial dysfunction and domestic violence. Problem gambling also has deleterious, long term effects on the mental and physical health of partners and children. Vulnerable groups include adolescents and young adults, socio-economically disadvantaged subpopulations, and specific ethnic minorities. The project's focus on identifying physiological patterns specific to problem gamblers represents an important first step in the development of an early screening test and timely interventions for at-risk individuals.Read moreRead less