Trauma And Recovery: Understanding And Treating Posttraumatic Stress Disorder In Refugees
Funder
National Health and Medical Research Council
Funding Amount
$431,000.00
Summary
Refugees report high rates of posttraumatic stress disorder (PTSD), however, a lack of understanding of the processes underlying refugee mental health has limited the effective treatment of this disabling disorder. My research program will overcome these barriers by uncovering core mechanisms and developing a targeted intervention to reduce PTSD symptoms in refugees. My research will advance knowledge about refugee mental health, and inform best-practice clinical care of refugees.
Step Up: A Technology-enhanced Stepped Psychological Intervention For Strengthening Adaptive Capacity And Treating Post-traumatic Comorbidities In Refugees
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
There is a major translational gap in rolling out psychotherapeutic treatments into readily accessible public health interventions for refugees. This project examines the feasibility and effectiveness of a technology-enhanced stepped psychological intervention designed to build resilience (Step 1) and manage traumatic stress symptoms and related comorbidities in traumatized refugees to ensure they have an enhanced capacity to adapt to the new environment post trauma.
How well people perform in everyday situations is often determined by memory function. When required to perform under stress memory performance is often affected. The effect of a psychological stress test on memory function in healthy volunteers and the ability of a dietary supplement, tyrosine, to prevent the effects will be studied. The data may suggest that depletion amino acids is responsible for the decrements in performance that are evident after an acute stressor.
Biopsychosocial Risk And Protective Factors Of Trauma Exposure In First Responders: A Longitudinal Investigation
Funder
National Health and Medical Research Council
Funding Amount
$1,137,427.00
Summary
Investigating individual differences in response to stress is crucial to improving both psychotherapy and pharmacotherapy for individuals at high risk for exposure to trauma. This world-first project will investigate pre and post-trauma psychological and biological trajectories associated with health outcomes in first-responders, contributing significantly towards our fundamental understanding of the biology of risk and resilience to trauma exposure, a key health issue.
Optimising Mental Health And Quality Of Life For Australia’s Military Personnel And Veterans With PTSD
Funder
National Health and Medical Research Council
Funding Amount
$728,958.00
Summary
Military personnel can experience a range of traumatic events throughout their careers, and many develop posttraumatic stress disorder (PTSD) as a result. Effective treatments for PTSD are available but involve seeing a mental health professional weekly for several months, which can be a difficult commitment for many military personnel and veterans to make. This project investigates whether standard treatment for PTSD is as effective when it’s delivered intensively in a shorter period of time.
The Phenomenology And Treatment Of Emotion Dysregulation In Traumatized Refugees
Funder
National Health and Medical Research Council
Funding Amount
$309,558.00
Summary
Refugee mental health is a crucial public health concern in Australia, however little is known about how to treat psychological disorders in refugees. While difficulty regulating emotions has been strongly linked to mental health problems following trauma, no research has studied this in refugees. This research program uses qualitative, quantitative and experimental methods to test a model of emotion dysregulation in refugees, and evaluates the impact of a treatment designed to improve emotion r ....Refugee mental health is a crucial public health concern in Australia, however little is known about how to treat psychological disorders in refugees. While difficulty regulating emotions has been strongly linked to mental health problems following trauma, no research has studied this in refugees. This research program uses qualitative, quantitative and experimental methods to test a model of emotion dysregulation in refugees, and evaluates the impact of a treatment designed to improve emotion regulation and general mental health in refugees.Read moreRead less
Chronic or extreme reactions to stress can lead to pathological conditions such as long term anxiety states, depression and panic disorders. Stress related disease also contributes to other major health problems such as heart disease and disorders of the immune system. These disease states include some of the major medical problems of our times. This proposal is to define genes which may be involved in stress responsiveness, to further understand and treat stress related disease.
THE NEUROBIOLOGICAL BASIS OF INDIVIDUAL DIFFERENCES IN SUSCEPTIBILITY TO THE CONSEQUENCES OF STRESS
Funder
National Health and Medical Research Council
Funding Amount
$583,875.00
Summary
Stress plays a major role in the development and progression of many different mental health disorders. However, as we all know, the effects of stress on one person can be very different from its effects upon another. This is at least partly explained by differences in individual coping styles. When faced with a stressful situation without a ready solution, people tend to divide into two broad camps: those with an innate tendency to adopt passive coping strategies, such as avoidance, and those t ....Stress plays a major role in the development and progression of many different mental health disorders. However, as we all know, the effects of stress on one person can be very different from its effects upon another. This is at least partly explained by differences in individual coping styles. When faced with a stressful situation without a ready solution, people tend to divide into two broad camps: those with an innate tendency to adopt passive coping strategies, such as avoidance, and those that tend towards active coping strategies, such as attempting to take control of the situation. Previous studies have provided findings that suggest that passive coping is more common amongst sufferers of depression, post-traumatic stress disorder, and chronic pain syndrome than is active coping. But is this cause, or effect? And what are the intervening brain mechanisms? We attempt to address such questions in the present project using an animal model in which social conflict has been shown to trigger depression-like symptoms. In particular we wish to: (i) determine whether the patterns of brain activity triggered by social conflict are different for active vs. passive copers; (ii) determine whether the depression-like consequences of social conflict are more severe in passive than in active copers; (iii) determine whether differences in coping style and vulnerability to social conflict stress are due to the actions of a particular neurotransmitter, dopamine, in the prefrontal cortex of the brain; (iv) determine whether the actions of antidepressants might be attributable changes in prefrontal cortex dopamine function which in turn promote active coping in preference to passive coping. These studies will provide exciting new information about the neurobiological basis of individual differences in vulnerability to the harmful effects of stress, and thus will offer the hope of developing new ways of preventing devastating illnesses such as depression.Read moreRead less