Improving Outcomes For People With Depression In Community Settings: A Cluster RCT
Funder
National Health and Medical Research Council
Funding Amount
$803,554.00
Summary
Depression affects 350 million people worldwide. Given the pivotal role of primary care in the management of depression, effective strategies are needed to assist GPs in the delivery of patient-centred depression care. This study will test the effectiveness of providing GPs with education; as well as feedback about patients’ self-reported depressive scores using a standardised instrument and perceived need and preferences for help. This cluster RCT will be the first Australian trial of its kind.
A Cluster RCT Of A Novel Psychological Intervention To Reduce Depression Among At-risk Older Adults Transitioning To Residential Aged Care
Funder
National Health and Medical Research Council
Funding Amount
$893,152.00
Summary
Depression is common in aged care facilities, with many older adults finding the transition extremely difficult. We have developed a simple intervention to help new residents, including those with dementia, to adjust to life in aged care. This program focuses on key aspects of psychological wellbeing, and is designed for widespread use in aged care. We will evaluate the intervention to determine if it is superior to current care approaches in reducing depression and improving quality of life.
Phase-Based Treatment For Posttraumatic Stress Disorder In Traumatized Refugees
Funder
National Health and Medical Research Council
Funding Amount
$1,003,340.00
Summary
Refugees report high rates of posttraumatic stress disorder (PTSD). Low response rates to psychological interventions for PTSD in refugees may be explained by their failure to target co-morbid emotion regulation difficulties. In this project, we will test the efficacy of a phase-based intervention that first targets emotion regulation difficulties before implementing trauma-focused therapy to reduce PTSD in refugees. Findings will advance knowledge and inform clinical interventions for refugees.
Preventing Relapse Of Major Depressive Disorder In Youth: RCT Of A Novel Mindfulness-Based Cognitive Online Social Therapy
Funder
National Health and Medical Research Council
Funding Amount
$1,713,093.00
Summary
Youth depression is a serious illness that will afflict one in four young people. Despite the initial effectiveness of modern treatments, 52% to 85% of young people with depression will suffer repeated depressive episodes. The recurrence of youth depression makes it the greatest cause of disability during youth worldwide. The aim of this project is to assess the effectiveness of a novel mindfulness-based cognitive online social media intervention in preventing relapse in youth depression.
The Phenomenology And Treatment Of Emotion Dysregulation In Traumatized Refugees
Funder
National Health and Medical Research Council
Funding Amount
$242,631.00
Summary
Refugee mental health is a crucial public health concern in Australia. Difficulty regulating emotions has been strongly linked to psychological disorders after trauma, however no research has studied this in refugees. This research program uses experimental methods to test a model of emotion dysregulation in refugees, and evaluates the impact of a treatment designed to improve emotion regulation and general mental health in refugees.
Prolonged Grief Disorder (PGD) is a debilitating psychological condition that affects at least 10% of bereaved people. There is limited knowledge on treating PGD. At present only 50% of affected people benefit from the treatment of choice. This project will test an augmented treatment that attempts to increase the efficacy of treatment for bereaved people suffering PGD. This program will shape more effective programs for assisting the 100's of thousands of Australians who suffer PGD.
Improving Quality Of Life In Late Stage Bipolar Disorder: RCT Of A Novel Psychological Treatment
Funder
National Health and Medical Research Council
Funding Amount
$1,083,620.00
Summary
Hundreds of thousands of Australians have bipolar disorder and receive minimal benefit from existing drug and psychological treatments. ORBIT 2.0 is a new low-intensity online treatment using mindfulness strategies to improve quality of life in this poorly served ‘late stage’ group. Pilot testing suggests ORBIT is effective. This project will refine the intervention and is expected to confirm its clinical and cost effectiveness prior to international roll-out.
The Efficacy Of Behavioural Activation Therapy In Treating Depression Among Individuals With Opioid Dependence
Funder
National Health and Medical Research Council
Funding Amount
$733,908.00
Summary
Heroin dependence is a chronic relapsing condition, associated with high levels of psychopathology. On entry to treatment at least one quarter of heroin users meet criteria for Major Depression. The co-occurrence of heroin dependence and depression is associated with a range of harms and has been linked to poorer treatment outcomes. Despite this, practical and effective treatment options are scarce. The proposed international collaboration will contribute significantly to understanding of the tr ....Heroin dependence is a chronic relapsing condition, associated with high levels of psychopathology. On entry to treatment at least one quarter of heroin users meet criteria for Major Depression. The co-occurrence of heroin dependence and depression is associated with a range of harms and has been linked to poorer treatment outcomes. Despite this, practical and effective treatment options are scarce. The proposed international collaboration will contribute significantly to understanding of the treatment of this comorbidity.Read moreRead less
Acceptance And Commitment Therapy For Medication-resistant Psychosis: A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$558,200.00
Summary
In spite of advances in medication, approximately one third of people with schizophrenia continue to experience distressing symptoms such as hearing voices and paranoia. Psychological 'talking treatments' are effective in helping people to cope with and be less distressed by these experiences. This study will be the first trial of a new psychological treatment, called Acceptance and Commitment Therapy, which may be more effective, briefer and more easily provided than existing approaches.
A Randomized Controlled Trial Of Three Treatments For Anorexia Nervosa In Adults
Funder
National Health and Medical Research Council
Funding Amount
$606,447.00
Summary
This study will be the first to evaluate three promising new treatments for anorexia nervosa (AN) and anorexic type eating disorders in adults. The first treatment is a new therapy called Enhanced Cognitive Behaviour Therapy. The second treatment, the Maudsley Cognitive Motivational Therapy, was designed specifically to treat AN and the third treatment is called non-specific supportive clinical management. The study will be in the form of a multi-centre randomised treatment trial.