Continuity and change in the development of young children with autism. Autism is a severe condition affecting social interaction, communication, behaviour and interests. Parents of children with autism experience high levels of stress associated with the burden of caring. There is a high societal cost associated with the care of people with autism. Research shows outcome in autism is poor, but that early intervention may improve outcome. This project will identify specific early precursors of a ....Continuity and change in the development of young children with autism. Autism is a severe condition affecting social interaction, communication, behaviour and interests. Parents of children with autism experience high levels of stress associated with the burden of caring. There is a high societal cost associated with the care of people with autism. Research shows outcome in autism is poor, but that early intervention may improve outcome. This project will identify specific early precursors of autism which predict outcome. This will allow the development of targeted intervention to give children the best possible start in life and improve longterm outcome. Improvement to the outcome of people with autism will considerably reduce parental and family burden and cost to the community.Read moreRead less
Behaviour and emotional problems in young children with developmental delay. This research will provide health professionals, researchers and service providers with a reliable and valid measure to assess behaviour in young children with developmental delay. This will be the first instrument of its kind worldwide. The study will provide the largest and most comprehensive survey of behaviour and emotional problems in young children with developmental delay internationally to date. It will provide ....Behaviour and emotional problems in young children with developmental delay. This research will provide health professionals, researchers and service providers with a reliable and valid measure to assess behaviour in young children with developmental delay. This will be the first instrument of its kind worldwide. The study will provide the largest and most comprehensive survey of behaviour and emotional problems in young children with developmental delay internationally to date. It will provide information on the types of treatment that are needed for these children and what support is needed for their families. The outcomes of this study have the potential to promote the best possible start in life and long term mental health of this group of at risk and disadvantaged young Australians.Read moreRead less
The cognitive neuroscience of executive control: behavioural, physiological and genetic mechanisms. How genes influence our human abilities to think, reason and control behaviour has puzzled scientists for decades. The human genome project has allowed us to ask how individual genes influence these capacities. Understanding the genetics of these abilities provides a solid platform from which to launch gene discovery projects in clinical disorders where these abilities are compromised. The curr ....The cognitive neuroscience of executive control: behavioural, physiological and genetic mechanisms. How genes influence our human abilities to think, reason and control behaviour has puzzled scientists for decades. The human genome project has allowed us to ask how individual genes influence these capacities. Understanding the genetics of these abilities provides a solid platform from which to launch gene discovery projects in clinical disorders where these abilities are compromised. The current project is directly relevant to the genetics of mental disorders, such as attention deficit hyperactivity (ADHD), that place a large burden, both financially and emotionally, on our society. Understanding the genes and biological pathways that increase risk for mental disorders will ultimately lead to improved treatments for these conditions.Read moreRead less
Models of adolescent drug use and its consequences. Recent concerns surround the impact of drug abuse - particularly binge drinking, inhalant abuse and cannabis use - on the mental health of adolescents. Early drug use is associated with mental health problems although the mechanisms involved are not well characterised. The present proposal aims to use animal models to characterise substance abuse that occurs during the adolescent period and to investigate its effects on brain and behaviour. Inc ....Models of adolescent drug use and its consequences. Recent concerns surround the impact of drug abuse - particularly binge drinking, inhalant abuse and cannabis use - on the mental health of adolescents. Early drug use is associated with mental health problems although the mechanisms involved are not well characterised. The present proposal aims to use animal models to characterise substance abuse that occurs during the adolescent period and to investigate its effects on brain and behaviour. Increasing our knowledge of the causes and consequences of adolescent drug abuse will improve Australia's ability to confront this problem and to develop early interventions and treatments that minimise associated harms.Read moreRead less
Genes, neuroanatomy and family process: Predicting adolescent anxiety and depression. Whilst significant gains in outcomes have been obtained in other areas of health by focusing on early intervention and prevention, in the mental health field this approach has been limited by the paucity of developmentally targeted treatment and prevention strategies. This study will provide unique information regarding the risk processes that are operating during early and late adolescence, and will inform us ....Genes, neuroanatomy and family process: Predicting adolescent anxiety and depression. Whilst significant gains in outcomes have been obtained in other areas of health by focusing on early intervention and prevention, in the mental health field this approach has been limited by the paucity of developmentally targeted treatment and prevention strategies. This study will provide unique information regarding the risk processes that are operating during early and late adolescence, and will inform us about how the family environment can act to modulate the impacts of biological vulnerability on risk for mental disorder. This project will contribute to our understanding of who, and what, to target in early intervention and prevention strategies.Read moreRead less
Beyond psychopathology: Pathways to suicide in mentally well young adult males. Increased knowledge of risk factors for suicide among mentally well males can lead to better informed preventive health policies, earlier intervention and community education. The tragic impacts of suicide lead to long-term societal problems which result in disconnection and alienation, particularly for those who are left behind; findings from this study will assist development of initiatives aimed at increasing soci ....Beyond psychopathology: Pathways to suicide in mentally well young adult males. Increased knowledge of risk factors for suicide among mentally well males can lead to better informed preventive health policies, earlier intervention and community education. The tragic impacts of suicide lead to long-term societal problems which result in disconnection and alienation, particularly for those who are left behind; findings from this study will assist development of initiatives aimed at increasing social connectedness and awareness. Also, males compose the predominant workforce in Australia and the costs saved as a result of effective prevention initiatives may be enormous, given that economic costs to suicide are estimated at 900 million dollars annually. Read moreRead less
Studying the effects of repetitive transcranial magnetic stimulation with near Infrared spectroscopy. Repetitive transcranial magnetic stimulation (rTMS) is increasingly being used as a tool in studying human and animal brain function and in the treatment of brain disorders but there are fundamental gaps in our understanding of its basic mechanisms of action and hence our capacity to optimise protocols. This research will use near infrared spectroscopy to study the range of potential ways of alt ....Studying the effects of repetitive transcranial magnetic stimulation with near Infrared spectroscopy. Repetitive transcranial magnetic stimulation (rTMS) is increasingly being used as a tool in studying human and animal brain function and in the treatment of brain disorders but there are fundamental gaps in our understanding of its basic mechanisms of action and hence our capacity to optimise protocols. This research will use near infrared spectroscopy to study the range of potential ways of altering brain activity with rTMS. It will substantially enhance the applicability of the technique ultimately improving our knowledge of human and animal brain function and outcomes for patients with depression and other disorders. It will help reinforce Australia as a leading country in the development of brain stimulation techniques.Read moreRead less
An Investigation into Suicidal Behaviours by Males during the Process of Marital and De Facto Separation. The project has a likelihood of reducing rates of fatal and non-fatal suicidal behaviour by high-risk groups such as males aged 25 - 44, and growing Australian populations such as the separated/divorced. The anticipated saving of lives, injuries, and mental distress is expected to achieve substantial and sustainable cutback in individual, corporate and public expenditure on mental health, i ....An Investigation into Suicidal Behaviours by Males during the Process of Marital and De Facto Separation. The project has a likelihood of reducing rates of fatal and non-fatal suicidal behaviour by high-risk groups such as males aged 25 - 44, and growing Australian populations such as the separated/divorced. The anticipated saving of lives, injuries, and mental distress is expected to achieve substantial and sustainable cutback in individual, corporate and public expenditure on mental health, injury control and suicide prevention by government, community and corporate agencies. Time and personnel resources utilised by the police, ambulance, coroner, hospital, and insurance departments can be diverted from highly preventable suicides to other areas. Read moreRead less
A prospective study of the mental health of grandparents providing part-time child care for their preschool age grandchildren. This project addresses national research priorities and will identify the characteristics of a high-risk subgroup of Australian grandparents for whom the childcare burden has a deleterious impact on health and well being. Results will enable development of improved approaches to education and awareness in health professionals and the lay community about this subgroup, fa ....A prospective study of the mental health of grandparents providing part-time child care for their preschool age grandchildren. This project addresses national research priorities and will identify the characteristics of a high-risk subgroup of Australian grandparents for whom the childcare burden has a deleterious impact on health and well being. Results will enable development of improved approaches to education and awareness in health professionals and the lay community about this subgroup, facilitating early identification and intervention. The study will provide evidence-based guidance to policy makers about the most appropriate support services for grandparents involved in high levels of childcare, reducing their level of stress and improving the quality of the childcare they provide.
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Recognising, assessing, and managing high risk stalking behaviour: An evidence-based approach. Developing effective methods of assessing and treating stalkers will directly impact the health and safety of thousands of stalking victims across Australia, and reduce the number of stalkers coming into contact with the criminal justice system. Application of the assessment and treatment tools developed during this project by mental health and corrective services around Australia will help to reduce p ....Recognising, assessing, and managing high risk stalking behaviour: An evidence-based approach. Developing effective methods of assessing and treating stalkers will directly impact the health and safety of thousands of stalking victims across Australia, and reduce the number of stalkers coming into contact with the criminal justice system. Application of the assessment and treatment tools developed during this project by mental health and corrective services around Australia will help to reduce physical and psychological harm experienced by both stalkers and their victims. The development and implementation of practical and effective strategies that lessen the impact of stalking will reduce the burden of mental ill-health caused by stalking, increase community safety, and reduce overall levels of victimisation in Australian society. Read moreRead less