Improving Repair In Dystrophic Muscles By Targeting ADAMTS5 Activity And Connective Tissue Remodeling
Funder
National Health and Medical Research Council
Funding Amount
$95,313.00
Summary
In muscle diseases such as muscular dystrophy degeneration exceeds its capacity to repair. Connective tissue remodelling facilitates the repair process; however the mechanisms by which it does this are poorly defined. This Project examines the role of connective tissue turn-over during muscle repair. It is anticipated that new insights into muscle regeneration will be gained to underpin development of therapeutics that promote muscle repair in skeletal muscle wasting diseases.