Kingdom switching microbial pathogens: the bioinformatics of mutation in the genomes of viruses and bacteria affecting crops, livestock and people. Some organisms that cause infectious diseases have moved between plants and vertebrates, either recently or repeatedly over evolutionary time. Switching between plants and vertebrates strongly influences the way these microbes mutate and evolve. We will search the genomic sequence databases for information about how the choice of host influences muta ....Kingdom switching microbial pathogens: the bioinformatics of mutation in the genomes of viruses and bacteria affecting crops, livestock and people. Some organisms that cause infectious diseases have moved between plants and vertebrates, either recently or repeatedly over evolutionary time. Switching between plants and vertebrates strongly influences the way these microbes mutate and evolve. We will search the genomic sequence databases for information about how the choice of host influences mutations in viral and bacterial genomes and model the evolutionary processes involved. This project will advance our understanding of the fine structure of microbial genomes and the importance of selection pressures on genes. It will lead to better disease management strategies for humans, and for domestic crops and livestock.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989759
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Australian Access to and Operation of Advanced Synchrotron Radiation Facilities at the Photon Factory. The primary national benefit of this application will be continued access by peer review for Australian scientists to the advanced synchrotron-radiation capabilities of the Australian National Beamline Facility and other complementary beamlines at the Photon Factory, Japan. This proposal is consistent with the National Research Priorities of An Environmentally Sustainable Australia, Promoting a ....Australian Access to and Operation of Advanced Synchrotron Radiation Facilities at the Photon Factory. The primary national benefit of this application will be continued access by peer review for Australian scientists to the advanced synchrotron-radiation capabilities of the Australian National Beamline Facility and other complementary beamlines at the Photon Factory, Japan. This proposal is consistent with the National Research Priorities of An Environmentally Sustainable Australia, Promoting and Maintaining Good Health and Frontier Technologies for Building and Transforming Australian Industries and will generate science to support and stimulate domestic industry, enhance the domestic knowledge base and international research profile, train students and future synchrotron scientists and foster domestic and international collaborations.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775482
Funder
Australian Research Council
Funding Amount
$500,000.00
Summary
Ultratrace element and isotope analysis facility. Analysis of trace concentrations of contaminants in food, water and biota is essential for proper environmental and human health protection, and the ability to analyse different isotopes of nutrients will improve our capability to develop techniques to fortify foods with essential micronutrients. The instrumentation will also assist our understanding of the geological processes, climate and environmental change and the formation and location of m ....Ultratrace element and isotope analysis facility. Analysis of trace concentrations of contaminants in food, water and biota is essential for proper environmental and human health protection, and the ability to analyse different isotopes of nutrients will improve our capability to develop techniques to fortify foods with essential micronutrients. The instrumentation will also assist our understanding of the geological processes, climate and environmental change and the formation and location of mineral deposits having economic potential in Australia. By improving forensic identification techniques, the instrumentation will allow identification and tracking of environmental contamination of the food chain and water supplies, and to identify and track criminal and terrorist activity. Read moreRead less
An evaluation of novel aluminosilicate materials based on modified kaolins for environmental applications. We have shown that simple and inexpensive modification of kaolin produces materials that adsorb large amounts of ammonium (N) and phosphate (P). We intend to evaluate and develop these materials for water treatment, so as to reduce N, P inputs into rivers and wetlands. The materials can then be used as fertilisers. Similarly addition of the materials to sandy soils to reduce leaching losses ....An evaluation of novel aluminosilicate materials based on modified kaolins for environmental applications. We have shown that simple and inexpensive modification of kaolin produces materials that adsorb large amounts of ammonium (N) and phosphate (P). We intend to evaluate and develop these materials for water treatment, so as to reduce N, P inputs into rivers and wetlands. The materials can then be used as fertilisers. Similarly addition of the materials to sandy soils to reduce leaching losses of N, P from fertilisers will be investigated. The major outcome of this research will be effective and inexpensive procedures for reducing eutrophication due to N, P from waste water and fertilisers.Read moreRead less
Discovery Indigenous Researchers Development - Grant ID: DI0989056
Funder
Australian Research Council
Funding Amount
$30,000.00
Summary
Adoption and Effective Use of Information Communication Technologies in Indigenous Communities in Australia. This project on Indigenous use of the internet aims to identify the reasons why Indigenous Australians are 69% less likely to access the Internet than their non-Indigenous counterparts as demonstrated in the last census. This research will assist in innovative policy development including the creation of a culturally-sensitive model to assist Indigenous communities to raise their use of c ....Adoption and Effective Use of Information Communication Technologies in Indigenous Communities in Australia. This project on Indigenous use of the internet aims to identify the reasons why Indigenous Australians are 69% less likely to access the Internet than their non-Indigenous counterparts as demonstrated in the last census. This research will assist in innovative policy development including the creation of a culturally-sensitive model to assist Indigenous communities to raise their use of computers and the internet. Ultimately the aim of the research is to provide mechanisms to engage Indigenous people with current technology to advance health, education and housing outcomes in their communities. Read moreRead less
Fundamentality. Australia is a world leader in metaphysical research. This project aims to strengthen the tradition of Australian metaphysics, by studying fundamentality, or the notion of being fundamental. It revives the classical monistic worldview on which we are interdependent and interrelated fragments of a greater whole. It thus connects the philosophical tradition of Plotinus, Spinoza, and Hegel to the physical picture of the cosmos as a single entangled quantum system, and so promises to ....Fundamentality. Australia is a world leader in metaphysical research. This project aims to strengthen the tradition of Australian metaphysics, by studying fundamentality, or the notion of being fundamental. It revives the classical monistic worldview on which we are interdependent and interrelated fragments of a greater whole. It thus connects the philosophical tradition of Plotinus, Spinoza, and Hegel to the physical picture of the cosmos as a single entangled quantum system, and so promises to deepen our understanding of our place in nature—while strengthening Australian leadership in the field.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0238960
Funder
Australian Research Council
Funding Amount
$940,000.00
Summary
High Performance Semiconductor Micromachining Facility. The purpose of this project is to make available to the Australian semiconductor research community a facility to undertake specialist deposition and etching tasks needed for fabrication of next generation solar cells, microelectronics, optronics, and micro-electromechanical systems. The facility will have the flexibility to allow independent control of major process parameters, allowing development of new fabrication technologies which wi ....High Performance Semiconductor Micromachining Facility. The purpose of this project is to make available to the Australian semiconductor research community a facility to undertake specialist deposition and etching tasks needed for fabrication of next generation solar cells, microelectronics, optronics, and micro-electromechanical systems. The facility will have the flexibility to allow independent control of major process parameters, allowing development of new fabrication technologies which will be generic to a wide range of semiconductor materials. In particular, the facility will be unique in its ability to perform processes at low temperatures, and under conditions that allow optimisation of the deposition and etching processes, without compromising the performance of delicate devices or exceeding the maximum process temperature limitations found in many mainstream semiconductor materials technologies.Read moreRead less
Perception, interpretation, and the explanation of delusional beliefs. The occurrence of bizarrely false beliefs, called delusions, presents challenges, not only for clinical psychiatric practice, but also for psychology, neuroscience, and philosophy. The aim of this project is to make a distinctively philosophical contribution to our understanding of delusional beliefs by addressing three philosophical questions raised by the study of delusions, questions about perception, interpretation, and e ....Perception, interpretation, and the explanation of delusional beliefs. The occurrence of bizarrely false beliefs, called delusions, presents challenges, not only for clinical psychiatric practice, but also for psychology, neuroscience, and philosophy. The aim of this project is to make a distinctively philosophical contribution to our understanding of delusional beliefs by addressing three philosophical questions raised by the study of delusions, questions about perception, interpretation, and explanation. Answers to these questions will constitute substantial contributions to three central areas of philosophy, but their significance also extends beyond philosophy. They will impact on the scientific investigation of delusions and will contribute indirectly to the treatment and rehabilitation of sufferers.
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Protein degradation in mammals. One mechanism by which the regulation of protein turnover occurs is the balance between the activity of enzymes responsible for the ubiquitination and deubiquitination of target proteins. The majority of targets of this second family of enzymes are unknown. This project proposes a method for the identification of the targets of two specific mammalian deubiquitinating enzymes in order to understand their function and to begin to explore this new research field. ....Protein degradation in mammals. One mechanism by which the regulation of protein turnover occurs is the balance between the activity of enzymes responsible for the ubiquitination and deubiquitination of target proteins. The majority of targets of this second family of enzymes are unknown. This project proposes a method for the identification of the targets of two specific mammalian deubiquitinating enzymes in order to understand their function and to begin to explore this new research field. Knowledge about this new aspect of protein degradation could provide a powerful tool to test the effect of the stabilisation or removal of specific proteins in the cell and also to develop new technologies in protein production.Read moreRead less
Learning from the development and implementation of Australia's National Indigenous Forestry Strategy. The project will undertake a multi-disciplinary study of the National Indigenous Forest Strategy (NIFS) in the native title era. A team comprising three academics from the ANU and key industry partners will collaborate with a very experienced APAI on the project. There has been considerable public policy concern and debate about the development problems facing Indigenous communities, particular ....Learning from the development and implementation of Australia's National Indigenous Forestry Strategy. The project will undertake a multi-disciplinary study of the National Indigenous Forest Strategy (NIFS) in the native title era. A team comprising three academics from the ANU and key industry partners will collaborate with a very experienced APAI on the project. There has been considerable public policy concern and debate about the development problems facing Indigenous communities, particularly in regional and remote Australia. Forestry offers one option for economic initiative, especially on the significant Indigenous estate. This project will inform and monitor the evolving NIFS and canvass options for policy-realistic and culturally-acceptable ways that forestry can ameliorate Indigenous socio-economic disadvantage.Read moreRead less