Structural Analysis Of Poxvirus Immature Particles And Spheroids
Funder
National Health and Medical Research Council
Funding Amount
$387,489.00
Summary
Despite the eradication of smallpox by vaccination, poxviruses remain a threat to public health because of bioterrorist scares from kept variola stocks and because of the possible emergence of other poxvirus pathogens from the extensive animal reservoir. The structural analysis of the assembly of poxvirus will not only improve our knowledge of fundamental processes, highly conserved in DNA viruses, but could also provide valuable targets for the rational design of antiviral drugs.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100121
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Three-dimensional super-resolution nanophotonic fabrication facility. This stimulated emission depletion microscopy nanophotonic fabrication facility will be the first nanophotonic fabrication facility that is able to achieve optical resolution far beyond the diffraction limit, which will facilitate breakthroughs in cutting-edge nanotechnology research areas.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100199
Funder
Australian Research Council
Funding Amount
$367,900.00
Summary
Advanced Synthesis System for Two-Dimensional Nanomaterials. Advanced synthesis system for two-dimensional nanomaterials:
This project aims to establish the first synthesis facility in Australia for growing large-area and atomically thin two-dimensional (2-D) nanomaterials including graphene, boron nitride, metal dichalcogenides, metal oxide and nitride nanosheets. Such materials are emerging and innovative materials that possess many properties desirable for energy, electronic, biological, and ....Advanced Synthesis System for Two-Dimensional Nanomaterials. Advanced synthesis system for two-dimensional nanomaterials:
This project aims to establish the first synthesis facility in Australia for growing large-area and atomically thin two-dimensional (2-D) nanomaterials including graphene, boron nitride, metal dichalcogenides, metal oxide and nitride nanosheets. Such materials are emerging and innovative materials that possess many properties desirable for energy, electronic, biological, and environmental related applications. This facility is designed to underpin breakthrough science by providing high-quality large-sized materials to researchers for both fundamental and application research. This new synthesis capability would foster advances in the fundamental understanding of 2-D nanostructures and the development of devices with broad applications in energy conversion and storage, environmental protection, and life sciences.Read moreRead less
Development of Metal-Titania Core-Shell Nanostructures for Photocatalysis. The aim of this project is to develop innovative techniques for the synthesis of advanced nanomaterials for pollutant removal and antibacterial applications. Improving the photocatalysis efficiency of titanium oxide (TiO2) is critical in energy and environmental applications. This project aims to develop innovative strategies to prepare metal–TiO2 core-shell nanostructures, in which metals (eg gold, silver) can be used as ....Development of Metal-Titania Core-Shell Nanostructures for Photocatalysis. The aim of this project is to develop innovative techniques for the synthesis of advanced nanomaterials for pollutant removal and antibacterial applications. Improving the photocatalysis efficiency of titanium oxide (TiO2) is critical in energy and environmental applications. This project aims to develop innovative strategies to prepare metal–TiO2 core-shell nanostructures, in which metals (eg gold, silver) can be used as light absorbers for visible incident light and generate intense electromagnetic fields, thus improving efficiency.Read moreRead less
The Complementary Effects Of Matrilins And WARP On Chondrogenesis Through TGF-beta Signaling
Funder
National Health and Medical Research Council
Funding Amount
$327,428.00
Summary
Osteoarthritis (OA), characterized by degeneration of articular cartilage matrix structure, is one of the most common types of arthritis. Although it is known that aging is a leading factor, the exact cause of degeneration of articular cartilage is not well understood. In order to aid the discovery of treatments and diagnostic tools for this joint disease, understanding functional and mechanistic properties of cartilage specific proteins, namely matrilins and WARP, is essential.
Programming soft plasmene nanosheets with living RAFT functional polymers. This project aims to use recently discovered plasmene to demonstrate programmable materials properties using living RAFT polymeric ligands. Plasmene is free-standing, one-particle-thick, superlattice sheets of plasmonic nanoparticles. It represents a conceptually new class of two-dimensional metamaterials with broad applications in energy, environment, sensors and optoelectronic devices. This project expects to generate n ....Programming soft plasmene nanosheets with living RAFT functional polymers. This project aims to use recently discovered plasmene to demonstrate programmable materials properties using living RAFT polymeric ligands. Plasmene is free-standing, one-particle-thick, superlattice sheets of plasmonic nanoparticles. It represents a conceptually new class of two-dimensional metamaterials with broad applications in energy, environment, sensors and optoelectronic devices. This project expects to generate new knowledge and patentable technologies, and advance Australian worldwide standing in the field of nanotechnology and polymer science.Read moreRead less
Assembly Of Mitochondrial Respiratory Chain Complexes And Their Defects Associated With Disease.
Funder
National Health and Medical Research Council
Funding Amount
$413,431.00
Summary
Mitochondrial “respiratory chain complexes are multi-subunit assemblies that function to produce most of our cellular energy. Defects in the assembly of these complexes can result in mitochondrial disease, including infant death. The assembly of the respiratory complexes is a complicated procedure and the mechanisms involved in disease remain elusive. This work will aid in our understanding of how these protein complexes are built and how defects in their assembly can cause disease.
Organically-Capped Copper Nanowires for Soft Electronic Skin Sensors. Soft skin-like electronics can enable applications that are impossible to achieve with today's rigid circuit board technologies. However, it is difficult to realise such future soft electronics with traditional materials and conventional manufacturing methodologies. This project aims to synthesise novel organically-capped copper nanowires as electronic inks (e-inks) for developing cost-effective, soft, stretchable conductor (e ....Organically-Capped Copper Nanowires for Soft Electronic Skin Sensors. Soft skin-like electronics can enable applications that are impossible to achieve with today's rigid circuit board technologies. However, it is difficult to realise such future soft electronics with traditional materials and conventional manufacturing methodologies. This project aims to synthesise novel organically-capped copper nanowires as electronic inks (e-inks) for developing cost-effective, soft, stretchable conductor (e-skin) sensors, which are wearable for monitoring blood pulses, body motions and hand gestures in real-time and in situ. This is expected to advance our knowledge in nanotechnology and generate patentable technologies in soft e-skin sensors, and to bring significant scientific and economic gains to Australia.Read moreRead less
Developing Multi-Scale Technologies for Two-Dimensional Metal Nanoparticle Superlattice Sheets. Nanoparticle superlattices refer to highly ordered nanoparticle arrays, which are a new class of crystalline materials with collective properties different from those of bulk phase crystals, isolated nanocrystals and even disordered nanocrystal assemblies. However nanoparticle superlattice is still in the embryonic stage of development due to the lack of multiscale technologies. This project aims to d ....Developing Multi-Scale Technologies for Two-Dimensional Metal Nanoparticle Superlattice Sheets. Nanoparticle superlattices refer to highly ordered nanoparticle arrays, which are a new class of crystalline materials with collective properties different from those of bulk phase crystals, isolated nanocrystals and even disordered nanocrystal assemblies. However nanoparticle superlattice is still in the embryonic stage of development due to the lack of multiscale technologies. This project aims to develop such important technologies to produce two-dimensional nanoparticle superlattice sheets for novel energy-harvesting devices. This will generate new knowledge and important patentable technologies for future energy industries, contributing to further advance Australian knowledge base and build a greener world.Read moreRead less