Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100121
Funder
Australian Research Council
Funding Amount
$1,000,000.00
Summary
An analytical transmission electron microscope for the investigation of functional materials, earth processes and novel condensed matter. Sustainablity depends on the delivery of clean energy, pristine water and air, and the manufacture of consumer products with small environmental footprints. Modelling long-term impacts requires an understanding of the hydro-geological cycles. The technologies are well known—efficient electronics, fuel cells, lightweight composites, and so on—but delivery is ....An analytical transmission electron microscope for the investigation of functional materials, earth processes and novel condensed matter. Sustainablity depends on the delivery of clean energy, pristine water and air, and the manufacture of consumer products with small environmental footprints. Modelling long-term impacts requires an understanding of the hydro-geological cycles. The technologies are well known—efficient electronics, fuel cells, lightweight composites, and so on—but delivery is not straightforward. It is clear, however, that novel materials manipulated at fine scales will be key. Transmission electron microscopy (TEM) guides the development of sustainable technologies. The new TEM facility at ANU will accelerate current studies, by enhancing the materials research portfolio, and extending national and international collaborations in materials, geological and earth sciences.Read moreRead less
Structural And Functional Analysis Of A Cancer-linked Co-regulator Complex
Funder
National Health and Medical Research Council
Funding Amount
$729,571.00
Summary
We seek to understand the mechanisms by which genes are switched on and off throughout our lifetime. A number of multi-component protein machines are involved in this process but their make-up and mechanism of action is not understood. We will investigate the structure and function of one of these machines that has been strongly linked to cancer.
Platelet Glycoprotein Proteolysis: Novel Mechanisms And Risk Factors
Funder
National Health and Medical Research Council
Funding Amount
$441,473.00
Summary
Platelets are the richest source of amyloid precursor protein (APP) in the body. Platelet ADAM10 regulates both the expression and function of the major platelet collagen receptor GPVI, and protective APP processing. Coagulation protein Factor X has a role in activation of ADAM10. This activation is disrupted in blood that has been treated with direct oral anticoagulant (DOAC) rivaroxaban. This grant will investigate the implications for people taking rivaroxaban on regulation of APP and GPVI.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100118
Funder
Australian Research Council
Funding Amount
$1,800,000.00
Summary
UltraTEM: Resolving the structure of matter in space, energy and time. This project aims to establish a transmission electron microscope facility to analyse materials structure at the atomic level. A small number of atoms in critical locations governs the properties of materials from solar cells and catalysts to aerospace alloys, bio-sensors and quantum computers. To understand and engineer matter at this atomic level, tools are needed to characterise these critical atoms. This open access, nati ....UltraTEM: Resolving the structure of matter in space, energy and time. This project aims to establish a transmission electron microscope facility to analyse materials structure at the atomic level. A small number of atoms in critical locations governs the properties of materials from solar cells and catalysts to aerospace alloys, bio-sensors and quantum computers. To understand and engineer matter at this atomic level, tools are needed to characterise these critical atoms. This open access, national facility will be able to characterise matter at the atomic-level. Expected outcomes include better understanding of the natural world and advanced materials to solve problems in energy, technology, health, environment, communications, advanced manufacturing, transport and security.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100132
Funder
Australian Research Council
Funding Amount
$1,486,000.00
Summary
A triple beam microscope: new frontiers in materials nanocharacterisation. This project aims to establish a triple beam ion and electron microscope facility for the modification, preparation and characterisation of materials that have hitherto been too sensitive for high resolution analysis with charged particle beams. It is expected that materials will be studied artefact-free and at the nanoscale with twin ion beams and new detectors that allow novel imaging modes and extreme chemical sensitiv ....A triple beam microscope: new frontiers in materials nanocharacterisation. This project aims to establish a triple beam ion and electron microscope facility for the modification, preparation and characterisation of materials that have hitherto been too sensitive for high resolution analysis with charged particle beams. It is expected that materials will be studied artefact-free and at the nanoscale with twin ion beams and new detectors that allow novel imaging modes and extreme chemical sensitivity plus controlled atmosphere transfer to other instruments for correlative measurements. This unique facility should benefit research in many disciplines such as physics, chemistry, geology, pharmacy, materials, civil and chemical engineering by allowing first-ever observations of vital phenomena in diverse materials.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100023
Funder
Australian Research Council
Funding Amount
$650,000.00
Summary
Australian high field electron paramagnetic resonance facility. This project aims to establish Australia’s first a high-field (3 T, 94 GHz) high-field pulse electron paramagnetic resonance (EPR) facility. EPR is a powerful technique to study chemical, biological and materials systems. It represents a sensitive, non-invasive, site-selective spectroscopy for the analysis of both molecular and macroscopic properties. This facility will allow the further development and implementation of new multidi ....Australian high field electron paramagnetic resonance facility. This project aims to establish Australia’s first a high-field (3 T, 94 GHz) high-field pulse electron paramagnetic resonance (EPR) facility. EPR is a powerful technique to study chemical, biological and materials systems. It represents a sensitive, non-invasive, site-selective spectroscopy for the analysis of both molecular and macroscopic properties. This facility will allow the further development and implementation of new multidimensional pulse EPR techniques, enabling domestic and international collaborations with diverse applications in structural biology, solvation science and catalysis.Read moreRead less
New Polymers for Cellulose-based Bioplastics. We will design new cellulose derivatives by combining carefully engineered synthetic polymers to cellulose. We will explore the fundamental science underpinning the manufacture of these bioplastics, and apply the concept to the design of two new materials, with (super)hydrophobic and antibacterial properties. These materials have the potential to replace synthetic plastics, which comprise one of the major outputs of the chemical industry worldwide. P ....New Polymers for Cellulose-based Bioplastics. We will design new cellulose derivatives by combining carefully engineered synthetic polymers to cellulose. We will explore the fundamental science underpinning the manufacture of these bioplastics, and apply the concept to the design of two new materials, with (super)hydrophobic and antibacterial properties. These materials have the potential to replace synthetic plastics, which comprise one of the major outputs of the chemical industry worldwide. Plastic is present everywhere in human life, but its manufacture and disposal have a strong negative impact on the environment; the new materials manufactured in this project are viable alternatives to plastics, and are sustainable from a production and disposal point of view.Read moreRead less