iMATCH: Independent mobility, active travel and children's health. Policy interventions are used across Australia to improve children's independent mobility, to increase children's physical activity levels and social interaction, and to generate more sustainable travel behaviour, particularly for the journey to school. iMATCH provides a holistic and inter-disciplinary evaluation of policy interventions than is undertaken for most evaluations of school travel and children's travel behaviour polic ....iMATCH: Independent mobility, active travel and children's health. Policy interventions are used across Australia to improve children's independent mobility, to increase children's physical activity levels and social interaction, and to generate more sustainable travel behaviour, particularly for the journey to school. iMATCH provides a holistic and inter-disciplinary evaluation of policy interventions than is undertaken for most evaluations of school travel and children's travel behaviour policies and programs. By controlling for the influence of the built and social environment, the project will provide the necessary support to justify these policy interventions and to identify key improvements for their delivery, supporting more sustainable and healthy lifestyles for Australia's children.Read moreRead less
Trustworthy positioning for intelligent transport systems. This project aims to develop a holistic approach for reliable positioning for Intelligent Transport Systems (ITS). This project will address the challenges of integrity monitoring in ITS when using satellite-based technology, its integration with other sensors, and when supported by the proposed Australia National Positioning Infrastructure. It will consider Australian geography, large area, and sparse population, and emphasise rural tra ....Trustworthy positioning for intelligent transport systems. This project aims to develop a holistic approach for reliable positioning for Intelligent Transport Systems (ITS). This project will address the challenges of integrity monitoring in ITS when using satellite-based technology, its integration with other sensors, and when supported by the proposed Australia National Positioning Infrastructure. It will consider Australian geography, large area, and sparse population, and emphasise rural transport. Expected primary outputs include algorithms, a detailed analysis of required systems and recommendations that will help prepare Australia for the importation of self-driving vehicles.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100118
Funder
Australian Research Council
Funding Amount
$500,000.00
Summary
The National Cycling Data and Analysis Platform (NCDAP) . A National Cycling Data and Analytics Platform to collect, integrate and communicate new and historic data on cycling infrastructure, attitudes, and behaviours. This project will address the significant issue of data fragmentation, pilot a national cycling survey, and develop a cycling toolkit to allow exploring and testing various cycling infrastructure scenarios. The platform will provide an open access e-Infrastructure to enable tracki ....The National Cycling Data and Analysis Platform (NCDAP) . A National Cycling Data and Analytics Platform to collect, integrate and communicate new and historic data on cycling infrastructure, attitudes, and behaviours. This project will address the significant issue of data fragmentation, pilot a national cycling survey, and develop a cycling toolkit to allow exploring and testing various cycling infrastructure scenarios. The platform will provide an open access e-Infrastructure to enable tracking social and cultural changes that influence transport choices, create effective behaviour change programs and prioritise cycling infrastructure investment. This project will contribute to healthier lifestyles, reduced traffic congestion and emissions and energy efficiency of Australia’s transport sector.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100051
Funder
Australian Research Council
Funding Amount
$200,000.00
Summary
Fabrication and characterisation facilities for lithium rechargeable batteries and supercapacitors. The facility, unlike any currently existing in Australia, will help researchers studying electrodes and cells at a high level. It will provide a new path to high-level research performance and will significantly enhance Australia’s research capability to bring new materials/technologies under development closer to application.
Alpha-2-Macroglobulin And The Transport And Uptake Of The Hormone, Hepcidin
Funder
National Health and Medical Research Council
Funding Amount
$533,541.00
Summary
Hepcidin is a peptide hormone that is a major regulator of iron metabolism. It has been suggested that hepcidin is free in the blood. However, we recently identified that hepcidin binds with alpha-2-macroglobulin (a2-M) in the plasma and this increases the efficacy of this peptide. The demonstration that a2-M plays a role in hepcidin biology will lead to a better understanding of hepcidin physiology, the development of methods for its measurement and improved treatment of iron related diseases.
Containment and Reduction of Rework in Transport Mega Projects. Mega transport projects (>$1 billion) are poorly managed during their construction with significant cost and schedule overruns and benefit shortfalls regularly being experienced. Having to perform rework has been identified as a major factor that contributes to these unintended consequences. As there has been limited research that has empirically examined rework causation, an inability to develop effective rework containment and red ....Containment and Reduction of Rework in Transport Mega Projects. Mega transport projects (>$1 billion) are poorly managed during their construction with significant cost and schedule overruns and benefit shortfalls regularly being experienced. Having to perform rework has been identified as a major factor that contributes to these unintended consequences. As there has been limited research that has empirically examined rework causation, an inability to develop effective rework containment and reduction strategies prevails. This research aims to develop a theoretical model that can be used to develop robust containment and reduction strategies to mitigate the adverse economic, productivity and safety consequences that materialize from performing rework during the construction of mega transport projects.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100203
Funder
Australian Research Council
Funding Amount
$956,700.00
Summary
Novel diagnostics capabilities in reacting, particle-laden flows. This project aims to establish innovative capabilities for advanced diagnostics techniques to be applied in reacting, particle-laden flows over a range of pressures. The complementary measurements are expected to provide an unprecedented understanding of the dynamics of liquid fragments and solid particles in flames. The resulting data, and improved knowledge, will set the framework for more effective predictive methods that assis ....Novel diagnostics capabilities in reacting, particle-laden flows. This project aims to establish innovative capabilities for advanced diagnostics techniques to be applied in reacting, particle-laden flows over a range of pressures. The complementary measurements are expected to provide an unprecedented understanding of the dynamics of liquid fragments and solid particles in flames. The resulting data, and improved knowledge, will set the framework for more effective predictive methods that assist in the design of cleaner and efficient processes that benefit a range of applications, from engine design to the generation of new fuels, and the flame synthesis of novel materials.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100157
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
Confocal and single molecule microscopes for systems microscopy. This project aims to establish Australia’s first system microscopy facility with dedicated live-cell confocal and single-molecule fluorescence microscopes. In systems microscopy, the imaging workflow is automated so that large and unbiased data sets of the spatiotemporal organisation of molecules and cells can be generated. Combined with statistical and bioinformatics analyses, image-derived data provides system-wide information th ....Confocal and single molecule microscopes for systems microscopy. This project aims to establish Australia’s first system microscopy facility with dedicated live-cell confocal and single-molecule fluorescence microscopes. In systems microscopy, the imaging workflow is automated so that large and unbiased data sets of the spatiotemporal organisation of molecules and cells can be generated. Combined with statistical and bioinformatics analyses, image-derived data provides system-wide information that is not easily obtainable with other approaches. The project will enable Australian researchers to image and analyse the full complexity of biological systems, potentially transforming cell biology, drug development and understanding the molecular basis of disease. It will also demonstrate how the capacity of microscopy facilities can be enhanced and bias in imaging data reduced by automating data acquisition and mining of image-based data.Read moreRead less
Exploring the gene regulation networks governing mitochondrial biogenesis in Arabidopsis. Mitochondria, subcellular organelles that perform many functions indispensable to plant growth and productivity, are dynamic compartments whose protein complement changes dramatically during plant development and under stress. Yet, the cellular processes that regulate the production of these organelles are virtually unknown. By combining conventional approaches with an extremely powerful holistic method for ....Exploring the gene regulation networks governing mitochondrial biogenesis in Arabidopsis. Mitochondria, subcellular organelles that perform many functions indispensable to plant growth and productivity, are dynamic compartments whose protein complement changes dramatically during plant development and under stress. Yet, the cellular processes that regulate the production of these organelles are virtually unknown. By combining conventional approaches with an extremely powerful holistic method for simultaneously examining the expression patterns of every gene in the model plant Arabidopsis, this project will identify proteins that regulate mitochondrial biosynthesis and uncover the gene networks that these proteins control. The project outcomes will provide new opportunities for the rational manipulation of plant growth and productivity.Read moreRead less