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Scheme : Linkage Projects
Australian State/Territory : WA
Research Topic : Protein Characterisation
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  • Researchers (29)
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  • Funded Activity

    Linkage Projects - Grant ID: LP140100919

    Funder
    Australian Research Council
    Funding Amount
    $300,000.00
    Summary
    Development of Canonical Mist Filter Models. Over one million tonnes of oil (mist) is wasted every year – and emitted to the atmosphere through inefficient filtration. Over 50 per cent of energy usage in most process industries is for filtration and separation processes, yet mist filters and separators are largely designed by trial and error, resulting in sub-optimal, inefficient designs. Recent advances by the research team have, only now, made it possible to develop accurate models for such sy .... Development of Canonical Mist Filter Models. Over one million tonnes of oil (mist) is wasted every year – and emitted to the atmosphere through inefficient filtration. Over 50 per cent of energy usage in most process industries is for filtration and separation processes, yet mist filters and separators are largely designed by trial and error, resulting in sub-optimal, inefficient designs. Recent advances by the research team have, only now, made it possible to develop accurate models for such systems. This work intends to be the first to develop accurate, broadly applicable models for all processes in mist filters, thereby providing immense process efficiency benefits, together with improved worker and environmental protection, and less wastage of dwindling oil resources.
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    Active Funded Activity

    Linkage Projects - Grant ID: LP170100108

    Funder
    Australian Research Council
    Funding Amount
    $365,608.00
    Summary
    Quantitative structural health assessment of large membrane-like structures. This project aims to develop a new approach, based on remote sensing and computational modelling, to assess and manage the structural health of large floating covers used for odour control and biogas harvesting to prevent unexpected failures. The project has potential benefits for high-value-added manufacturing and maintenance of these floating covers by Australian industry.
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    Active Funded Activity

    Linkage Projects - Grant ID: LP220100131

    Funder
    Australian Research Council
    Funding Amount
    $362,000.00
    Summary
    Transforming pastefill delivery system for next-generation mining industry. This project aims to develop a new type of mining pipeline design platform that can vastly improve pastefill (slurry) delivery systems. Using an Artificial Intelligence-based design platform, understanding complex and numerous variables in the fluid dynamics of abrasive pastefill flow will inform a new pipeline design. Consisting of a vertical casing, with our new composite pipeline chokes to replace costly friction loop .... Transforming pastefill delivery system for next-generation mining industry. This project aims to develop a new type of mining pipeline design platform that can vastly improve pastefill (slurry) delivery systems. Using an Artificial Intelligence-based design platform, understanding complex and numerous variables in the fluid dynamics of abrasive pastefill flow will inform a new pipeline design. Consisting of a vertical casing, with our new composite pipeline chokes to replace costly friction loops, improvements in flow efficiency and pipeline deterioration can significantly reduce maintenance costs. This novel and adaptable next-generation pipeline design and analysis platform can be employed by the manufacturing and mining sectors for pipeline failure analysis, managing production and developing new products.
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    Funded Activity

    Linkage Projects - Grant ID: LP0347870

    Funder
    Australian Research Council
    Funding Amount
    $84,099.00
    Summary
    A proteomic approach to identifying the signaling pathway(s) by which acute oxidative stress causes cell death by apoptosis. Oxidative stress following traumatic injury (heart attack or stroke) is known to activate signaling pathways leading to programmed cell death (apoptosis). The aim of this project is to develop methods to identify the signaling proteins involved. Identifying proteins involved in causing cell death will be useful in developing diagnostic tools as well as providing potential .... A proteomic approach to identifying the signaling pathway(s) by which acute oxidative stress causes cell death by apoptosis. Oxidative stress following traumatic injury (heart attack or stroke) is known to activate signaling pathways leading to programmed cell death (apoptosis). The aim of this project is to develop methods to identify the signaling proteins involved. Identifying proteins involved in causing cell death will be useful in developing diagnostic tools as well as providing potential therapeutic possibilities.
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    Active Funded Activity

    Linkage Projects - Grant ID: LP190100433

    Funder
    Australian Research Council
    Funding Amount
    $558,400.00
    Summary
    Characterising the transport and delivery of oligonucleotides . Short RNA and DNA molecules represent a class of macromolecules that have great potential, but to facilitate their trafficking across cellular and membrane barriers into specific sites of action is challenging. This project aims to develop and apply novel imaging approaches to track them in cells and tissues. Expected outcomes include better understanding of the trafficking across cellular and membrane barriers, and improved imaging .... Characterising the transport and delivery of oligonucleotides . Short RNA and DNA molecules represent a class of macromolecules that have great potential, but to facilitate their trafficking across cellular and membrane barriers into specific sites of action is challenging. This project aims to develop and apply novel imaging approaches to track them in cells and tissues. Expected outcomes include better understanding of the trafficking across cellular and membrane barriers, and improved imaging tools that could be used to further study the molecular mechanisms of accumulation, metabolism and trafficking of these molecules. This project should provide new strategies to target these molecules to specific cells and tissues, which have significant social and economic benefits to the Australian community.
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